Systemic Lupus Erythematous & the association with genes on the X chromosome and sex biased towards women.

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Citations

1. Harris VM, Koelsch KA, Kurien BT, Harley ITW, Wren JD, Harley JB, Scofield RH. 2019. Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis. Frontiers in Immunology. 10. doi:10.3389/fimmu.2019.02160.

2. Migeon BR. 2020. X-linked diseases: susceptible females. Genetics in Medicine: Official Journal of the American College of Medical Genetics. 22(7):1156–1174. doi:10.1038/s41436-020-0779-4. [accessed 2020 Aug 17]. https://pubmed.ncbi.nlm.nih.gov/32284538/.

3. Youness A, Miquel C-H, Guéry J-C. 2021. Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases. International Journal of Molecular Sciences. 22(3):1114. doi:10.3390/ijms22031114.

4. Odhams CA, Roberts AL, Vester SK, Duarte CST, Beales CT, Clarke AJ, Lindinger S, Daffern SJ, Zito A, Chen L, et al. 2019. Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus. Nature Communications. 10(1). doi:10.1038/s41467-019-10106-2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520347/