Write a reflection of a research assignment
Group G
Sijia Liu V00846180
Zening Li V00836651
Yanni Yang V00827483
Miffy Chen V00899149
Econ 317 Group Assignment 4
· Health condition and describe:
The main goal of our group is to do health intervention for the elder people aged 75 years and over, so it is mainly aimed at the senile diseases. We chose senile pneumonia this time. This is a temporary disease. Clinical manifestations are atypical, such as insidious onset, often without cough, expectoration, fever, chest pain and other symptoms. More common symptoms are increased breathing frequency, shortness of breath or dyspnea. On the contrary, systemic toxic symptom is more common and can appear early, including spirit flagging, lack of power, loss of appetite, disgusting vomiting, fast heart rate, wrong rhythm of the heart, delirium, ambiguous consciousness, heavy blood pressure drops and coma. Based on the data from 1988 to 2002, for influenza and pneumonia hospitalizations in Ontario, females had an average annualized peak rate of 250/100 000 compared to 400/100 000 for males. (Eric, et al.,2004) in 2016, the death rate of for influenza and pneumonia in Canada is 17.2%. (Statista, 2019) As can be seen, senile pneumonia can lead to hospitalization and even death.
Reference:
ER IC J. CR IGHTON, et al. (2004). Influenza and pneumonia hospitalizations in Ontario: a time-series analysis. Epidemiol Infect. 132, 1167–1174.
Statistic. (2019). Influenza and pneumonia death rate Canada 2000-2016 .Retrieved March 22, 2019, from https://www.statista.com/statistics/434445/death-rate-for-influenza-and-pneumonia-in-canada/
· Questionnaire
As the interviewees are all Chinese, the questionnaires are provided in Chinese in interviews. After the visit, the result is rewritten in the English electronic version of the document.
· Relevant rating list:
Table 1
|
Visual scale |
Standard gamble |
Time trade-off |
|
|
1 |
38% |
70% |
30% |
|
2 |
30% |
20% |
10% |
|
3 |
30% |
0% |
10% |
|
4 |
20% |
30% |
30% |
|
5 |
56% |
50% |
100% |
· QALY list:
Table 2
|
Question No. |
QALY (visual scale) |
QALY(standard gamble) |
QALY(time trade-off) |
|
1 |
0.38 |
0.4 |
0.4 |
|
2 |
0.3 |
0.775 |
-0.8 |
|
3 |
0.3 |
0.82 |
-0.8 |
|
4 |
0.2 |
0.743 |
0.4 |
|
5 |
0.56 |
0.64 |
0.82 |
· QALY calculations:
· Visual scale measurement
QALY = (LH – L0)/(L1 – L0)
For No.1, LH=0.38, L0=0, L1=1.
QALY=0.38
Following the same method, the QALY for the left 4 perople:
|
No. |
QALY |
|
2 |
0.3 |
|
3 |
0.3 |
|
4 |
0.2 |
|
5 |
0.56 |
· Standard Gamble
For temporary health condition,
p + S x (1 – p) = H
H=QALY(heartburn)=0.82
For
p=0.7
S=(H-p)/(1-p)=0.4
Following the same method, the QALY for the left 4 perople:
|
No. |
QALY |
|
2 |
0.775 |
|
3 |
0.82 |
|
4 |
0.743 |
|
5 |
0.64 |
· Time trade-off
H = 1 - A/B x (1 – S)
S=QALY(heartburn)=0.82
A=one week
For No.1
B=0.3*one week
H=1-1/0.3*(1-0.82)=0.4
Following the same method, the QALY for the left 4 perople:
|
No. |
QALY |
|
2 |
-0.8 |
|
3 |
-0.8 |
|
4 |
0.4 |
|
5 |
0.82 |
· Discussion:
1. Were your QALY values close together or far apart?
According to Figure, we can say QALY values were far apart.
Figure 1
2. Did one method (SG or TTO) provide consistently higher or lower QALY values than the other? If so, how do you explain it?
Standard gamble provides consistently higher QALY values than visual scale measurement. In visual scale measurement, people's discomfort about pneumonia was actually very vague, and they may have randomly selected a value within a large acceptable range. It could be that standard gamble, with heartburn as a reference, gave people a clearer sense of the discomfort of pneumonia.
3. Do you think your interviewee’s characteristics affected the QALY measures? If so, which ones, and how? (e.g. Age, Gender, Cultural Background, whether they’d experienced the health state before)
Table 3
|
No. |
Gender |
Age |
visual |
SG |
TTO |
|
1 |
Female |
25 |
0.38 |
0.4 |
0.4 |
|
2 |
Male |
26 |
0.3 |
0.775 |
-0.8 |
|
3 |
Female |
50 |
0.3 |
0.82 |
-0.8 |
|
4 |
Male |
24 |
0.2 |
0.743 |
0.4 |
|
5 |
Male |
25 |
0.56 |
0.64 |
0.82 |
All interviewees are Chinese. Only No.3 had experienced pneumonia before.
According to the above summary table, we can see that no observed characteristics affects QALY significantly.
4. If you were to do this assignment again, what would you change to improve the reliability of your results?
We hope to collect more samples. We also plan to collect more detailed information on the basic information and characteristics of the interviewees.
· Summary
According to Table 2, we can see that the QALY values provided by different method vary a lot, so that different ways of interview will cause different psychological feelings and cognition. For the same measurement method, visual scale measurement and standard gamble both provide relatively centralized QALY values, although there is a deviation value. However, the QALY values obtained by time trade-off method are scattered, especially there are negative values. Negative values stand for more uncomfortable than death, which we think is unreasonable. Therefore, we believe that time trade-off is not effective in this application. Standard gamble provides heartburn as a reference, so we think people have a clearer understanding of the discomfort of pneumonia under this interview method, compared with visual scale measurement. All above, standard gamble is the most effective method in this application.
QALY
Visual scale 1 2 3 4 5 0.38 0.3 0.3 0.2 0.56 Standard gamble 1 2 3 4 5 0.7 0.2 0 0.3 0.5 Time trade-off 1 2 3 4 5 0.3 0.1 0.1 0.3 1
Group
G
Sijia
Liu
V00846180
Zening
L
i
V00836651
Yanni
Yang
V00827483
Miffy
C
hen
V00899149
Zhou
Zhou
V00892008
Econ
317
Group
Assignment
4
l
Health
condition
and
describe:
The
main
goal
of
our
group
is
to
do
health
intervention
for
the
elder
people
aged
75
years
and
over,
so
it
is
mainly
aimed
at
the
senile
diseases.
We
chose
senile
pneumonia
this
time.
This
is
a
temporary
disease.
Clinical
manifestations
are
atypical,
such
as
insidious
onset,
often
without
cough,
expectoration,
fever,
chest
pain
and
other
symptoms.
More
common
symptoms
are
increased
breathing
frequency,
shortness
of
breath
or
dyspnea.
On
the
contrary,
systemic
toxic
symptom
is
more
common
and
can
appear
early,
including
spirit
flagging,
lack
of
power,
loss
of
appetite,
disgusting
vomiting,
fast
heart
rate,
wrong
rhythm
of
the
heart,
delirium,
ambiguous
consciousness,
heavy
blood
pressure
drops
and
coma.
Based
on
the
data
from
1988
to
2002,
for
influenza
and
pneumonia
hospitalizations
in
Ontario,
females
had
an
average
annualized
peak
rate
of
250/100
000
compared
to
400/100
000
for
males.
(Eric,
et
al.,2004)
in
2016,
the
death
rate
of
for
influenza
and
pneumonia
in
Canada
is
17.2%.
(Statista,
2019)
As
can
be
seen,
senile
pneumonia
can
lead
to
hospitalization
and
even
death.
R
e
ference:
ER
IC
J.
CR
IGHTON,
et
al.
(2004).
Influenza
and
pneumonia
hospitalizations
in
Ontario:
a
time-series
analysis.
Epidemiol
Infect.
132,
1167
–
1174.
Statistic.
(2019).
Influenza
and
pneumonia
death
rate
Canada
2000-2016
.Retrieved
March
22,
2019,
from
https://www.statista.com/statistics/434445/death-rate-for-influenza-and-
pneumonia-in-canada/
l
Questionnaire
As
the
interviewees
are
all
Chinese,
the
questionnaires
are
provided
in
Chinese
in
interviews.
After
the
visit,
the
result
is
rewritten
in
the
English
electronic
version
of
the
document.
l
Relevant
rating
list:
Table
1
Questionnaire
No.
Visual
scale
Standard
gamble
Time
trade-off
1
38%
70%
30%
2
30%
20%
10%
3
30%
0%
10%
4
20%
30%
30%
5
56%
50%
100%
l
QALY
list: