study guide
Quizzes and Final Exam Study Guide
Ch. 3: Quality, patient safety and communication
· Review causes of potential areas of risks to patients receiving respiratory care
· Review proper technique to lifting heavy objects
· Review organizations responsible for quality and appropriateness of care given to Medicare beneficiaries
· Review parameters that require monitoring during ambulation
· Define: Voltage, current, Ohms, Amps
· Organ most sensitive of electrical shock: Heart
· Purpose of grounding electrical equipment
· Review how O2 contributes to severity of fire
· How is static electrical discharge minimized in the presence of O2
· RACE: what does it stand for
· Definition of channel in communication
· Nonverbal communication methods
· Communicating empathy towards your patients
· Factors that impact outcomes of communication between patient and practitioner
· How do you improve listening skills
· Review communication techniques
Ch. 4: Principles of infection prevention and control
· % of patients who develop hospital associated infections
· Primary source of infection in healthcare
· How do ETT contribute to risk of infection
· What are the risk factors that contribute to hospital associated infection (age, HIV…)
· Review different types of pathogen transmission routes
· Direct vs indirect transmissions
· Distance recommended to stay away from patients with SARS, COVID…
· Which diseases are airborne and require airborne isolation and use of N95
· Definition of surveillance
· Required vaccination for hospital employees (think about the ones you obtained to go to clinic)
· Cleaning and sterilization of equipment: First step is to clean the equipment
· Review Soap and its use to clean equipment
· Review which organisms are destroyed by disinfection agents
· Review what you must do to your hands after treating patients with C-Diff
· How do we transport patients with infections
· Indication for steam sterilization
· glutaraldehyde (≥2.0%) use and indications
· Time frame for hand washing
· ETO sterilization
· Most common respiratory equipment source of patient infections
· Ventilator circuit change frequency
· Which organisms are present with poorly disinfected bronchoscopes
· Review types of isolation- what is transmitted through droplets, direct contact…
· Prevention Bundle
· SVN and associated infections
Ch. 5: Ethical legal implications
· Definition of ethics/what does ethics attempt to answer
· Sanctions that apply when one breaks the law
· Importance of privacy/HIPAA
· Review AARC code of ethics
· Review terms: Autonomy, nonmaleficence, Justice, Role fidelity, veracity, beneficence. Malevolent deception, infidelity, double effect, distributive justice, compensatory justice
· Types of advanced directives
· When can confidentiality by breached
· Consequentialism
· Virtue ethics
· Tort, felony, misdemeanor, litigation, battery, slander, assault, negligence
· Res ipsa loquitur, Respondent superior
Ch. 16. Bedside Assessment of the Patient
· Purpose of an RT interview
· Social, personal and intimate space
· Leading questions
· Causes of increase drive to breathe
· Terms: orthopnea, platypnea, eupnea, apnea
· Factors of an effective cough
· Causes of dry non productive cough
· Terms: sputum, phlegm, mucus
· Terms: fetid, mucoid, purulent
· Hemoptysis, hematemesis
· Causes for pleuritic chest pain
· Terms: angina, myalgia
· Most common cause of pedal edema
· Critical elements of a patients past medical history, social and environmental history
· What is diaphoresis
· Causes for tripoding
· Altered sensorium leads to what characteristics
· What regulates body temperature
· Causes for hypo and hyperthermia
· Causes of tachycardia, tachypnea, bradypnea, bradycardia
· What is a differential diagnosis
· Causes of pulsus paradoxus
· Normal vital sign ranges, causes for increases and decreases
· Pulse pressure
· Pursed lip breathing indications/benefits
· Central cyanosis
· Causes of tracheal shifts
· Causes for JVD
· Causes of lymphadenopathy of the neck
· Barrel chest
· Terms: kyphosis, kyphoscoliosis, pectus carinatum, evactum
· Causes for neuro breathing patterns, increased ICP
· Cheyne stokes, biots, kussmauls, paradoxical
· Characteristics of an increased WOB
· Rapid shallow, indicative of atelectasis
· Prolonged exhalation associated with asthma, COPD
· Hoover’s sign
· Tactile fremitus, bronchophony
· Subcutaneous emphysema causes
· Auscultation and percussion technique
· Breath sound review
· Terms epigastric, precordium
· PMI
Ch. 17: Interpreting clinical lab data
· Components of a CBC
· Components and what It means to have elevated or decreased WBC count
· Causes for high/low Hb
· Causes for high/low WBC
· Causes for high/low platletes
· Bands/Segs
· Critical values vs reference range
· Types of anemia, MCH
· Ranges for electrolytes: K, HCO3, Ca, Cl, Na, Glucose
· Terms for high and low electrolytes (ex: hypokalemia)
· Purpose of a sweat chloride test
· Anion gap, causes for metabolic acidosis
· Creatinine what does it represent
· Liver enzymes
· Cardiac enzymes
· Causes for increased BNP
· Sputum sample and amount of epithelial cells
· Xpert® MTB/RIF in diagnosing TB infections
Ch. 11: Ventilation
· Review all lung volumes and capacities
· Primary function of the lungs
· Review: PA, PBS, PAO, Ppl
· Review all lung pressure gradients
· Review what occurs during normal inspiration and expiration
· Review surface tension, airway resistance, elastic forces
· Hysteresis
· Presence of surfactant does what
· Compliance: how is it calculated, normal values, dynamic vs static
· Causes for increases and decreased compliance
· Review VC, MIP
· Review airway resistance and causes for increased RAW, formula, normal value
· Poiseuille’s law
· Frictional resistance where does it occur, increases
· Equal pressure point (EPP)
· Force x distance
· Volume-pressure curve characteristics
· Rapid shallow breathing vs slow and deep, causes for each
· Normal oxygen consumption percent
· Regional factors that affect distribution of gas in the normal lung
· How is time constant computed
· Optimal peep, how is it set
· Best indicator for adequacy or effectiveness of alveolar ventilation
· Definition of hyperventilation, hyperpnea, hypoventilation
· Alveolar ventilation, formula, causes for increase and decrease
· Resting metabolic CO2 production and Oxygen consumption in ml/min
· VDphy what is the normal value, how do we overcome deadspace
· What can increase VD/VT
· Modified bohr equation used to calculate dead space
· Ve calculation
Ch. 12: Gas Exchange and Transport
· Definition of diffusion
· Amount of PAO2, PaO2, O2 in cells
· Amount of PACO2, PaCO2, CO2 in cells
· Casues for increased PACO2
· Primary determinant of PAO2, formula
· Approx. PAO2 on 100% FIO2 at sea level
· a/A ratio, PF ratio, A-a gradient/normal values
· highest PAO2 while breathing room air at sea level
· gas diffusion must occur by transversing through what layers (AC membrane, RBC membrane…)
· normal values of PO2 and PCO2 in mixed venous blood
· CO2 and CO diffuse faster than O2 across AC membrane, how many times
· Minimum amount of time that blood must take for pulmonary capillary transit for equilibrium of O2 to occur across the AC membrane
· Shunting vs Deadspace ventilation, V/Q mismatches
· How is O2 and Co2 carried in the blood
· CaO2, VO2 and DO2 formula
· Hamburger phenomenon
· SVO2 value
· O2 dissociation curve
· Bohr and Haldane effect
Ch. 36: Pharmacology
· All medication names and doses, frequency including:
· LAMA, LABA, SAMA, SABA, ICS, Combination drugs, mucolytics, bland aerosol, vasodilators, anti-infectives, anti-asthma
· Including: (know generic and brand names)
· Atovent
· Spiriva
· Albuterol
· Serevent
· Tudorza
· Trelegy
· Advair
· Symbicort
· Pulmicort
· Flovent
· Anoro
· Aclidium bromide
· Breo Elipta
· Dulera
· Racemic epinephrine
· Xopenex
· Vilanterol
· Arfomterol
· Tobi
· Mucomyst
· Dornase alfa
· Hypertonic Saline
· Indacterol
· Olodaterol
· Qvar
· Survanta
· Performist
· Duoneb, Combivent
· Nitric Oxide
· Ciciesonide
· Leukotrienes
· Arnuity Ellipta
· Pentamidine
· Lloprost
· Asmanex
· Know side effects, indications
· Mode of action of all drugs
· Receptor sites: Alpha 1, Beta 1-2, Muscarinic (M1-3)…adrenergic, anti-cholinergic
· Terms: Expectorant,Tolerance, Drug administration, pharmacokinetic, pharmacodynamic, bioavailability
· Use of MDI, DPI, SMI’s, holding chambers, SVN’s. Mesh nebulizers
· Advantages of inhaled medication route
· Catechol O-methyltransferase (COMT), phosphodiesterase, cholinesterase
· Use of I-neb
Ch. 37: Airway Management
· Indications for suctioning, suction technique/procedure steps, pre suction techniques
· Side effects/complications of suctioning
· Equipment needed for suctioning
· Vacuum pressures adult/peds/babies
· Suction catheter sizes
· Open vs closed suction techniques
· Percutaneous dilation tracheostomy vs surgical tracheostomy
· Intubation indications for oral and nasal
· Tracheostomy indications
· Artificial airway types
· ETT sizes (adults, peds, babies), intubation procedure and equipment required
· Murphy eye
· Purpose of cuff, cuff pressure monitoring, troubleshooting
· Trach types and components
· Miller vs macintosh
· Sniffing position, cricoid pressure
· Time frame for intubation attempt
· ETT confirmation procedure/location on CXR, ETT placement at lip
· Use of capnography
· Complications of intubation
· local anesthesia and vasoconstriction during nasal intubation
· limitations of using a laryngeal mask airway
· post extubation complications
· complications of trachestomy tubes
· cuff pressures
· weaning off a trachestomy tube
Ch. 39: Humidity and Aerosol Therapy
· Isothermic saturation boundary- location, how is it changed/shifted
· Goal of humidity therapy
· Indications to warm inspired air
· Consequences of not adding humidity to flows >4L/min
· Goals of delivering gases to nose/mouth: 50% RH, at 20-22 degrees C
· Goals delivering gases to hypopharynx: 95% RH at 29-32 C
· Goals delivering gases through artificial airways: 100% RH at 32-35 C
· Indications for cool humidified gas
· Humidifier vs nebulizer
· Factors that effect a humidifier performance
· Most important factor for a humidifier = temperature
· Calculation of relative humidity, body humidity
· Signs and symptoms of inadequate airway humidification
· Types of humidifiers
· relief valve on a bubble humidifier does what
· At high flow rates, what do some bubble humidifiers produce?
· Passover humidifier types
· Wick
· HME types/uses, effieicent rating/hazards
· Heated humidifier indications and operation
· Use of MDI while HME is in place
· When using nebulizers, where should you place them to minimize risk of contamination?
· heated-wire circuit use
· Hazards of bland aerosol
· Indications for water or isotonic saline aerosol, hypertonic
Ch. 40 Aerosol Drug Therapy
· Definition of a aerosol
· Types of nebulizers
· Aerosol output, density, deposition, sedimentation, inertial impaction, Brownian movement/diffusion
· Emitted dose
· Cascade impaction
· MMAD: ranges and where they deposit in the airway
· GSD
· Heterodisperse
· Know factors affect pulmonary deposition of an aerosol
· How do you increase deposition by inertial impaction
· Purpose of a sustained maximal inspiration
· Term aging
· How do you minimize risk of infection with aerosol drug therapy
· Know which drugs or drug categories have been associated with increased airway resistance and bronchospasm during aerosol administration
· Know which agents has been associated with increased intraocular pressure
· How do you decrease risk of thrush
· Limitations of DPI and breath actuated systems
· MDI use, propellants use, use on children…
· DPI use, advantages/disadvantages
· SVN use and design, how does it work, what happens if it is not upright position, if flow is set to high…
· Dead volume left with SVN
· How do you decrease infection with SVN use
· recommended dosage for continuous bronchodilator therapy (CBT)
· use and indications of peak flow meters
Ch. 41: Storage and delivery of Medical Gases
· Review therapeutic gases
· Know characteristics of O2, NO, He, N2, CO2, air
· Know what fractional distillation is
· Purity level of O2 per FDA
· Physical separation of O2 in home care setting
· Components of medical air compressors
· Hospital air compressors capable of maintaining 50 PSI and 100L/min
· Why and how is He used as a therapeutic gas
· Tanks: Colors, Tank factors, markings, DOT, formula for duration, testing and material made of, yolk system/PISS, ASSS, DISS, storage of tanks, full PSI
· How are gas vs liquid tanks measured for contents
· Liquid tank duration
· Bourdon gauge vs Thorpe tubes; how do regulators work, multiple stage/single stage, working pressures…
Ch. 42: Oxygen delivery devices
· Hight flow vs low flow, what are the characteristics of each
· All oxygen delivery devices: know flow/troubleshooting/indications and disadvantage and benefits for
· NRM
· Partial rebreathing
· NC
· HFNC
· Simple Mask
· Transtracheal catheter
· Venturi masks
· Reservoir cannulas
· Indications and benefits of O2 therapy; review SpO2 ranges for adults/children
· Heliox use, 70/30 and 80/20 factors, what device is used to deliver it
· Carbogen use
· Symptoms of severe hypoxemia
· Symptoms of hyperoxia/substernal chest pain
· O2 toxicity, how much FIO2 and for how long, consequences of O2 toxicity
· ROP, absorption atelectasis, hyaline membrane formation
· How do we minimize risk of fire hazard with O2 in use
· Approximate FIO2 with O2 devices
· High flow systems deliver at least what flow
· Total flow calculation
· O2 blending systems vs entrainment systems
· How do you confirm proper functioning of a blending system
· Enclosure systems, minimum flows required, indications
· NO therapy, indications, hazards, amount used
· NO2 what is it, issues with it
· Hyperbaric use, indications, settings, physiological effects
Ch. 43: Lung expansion therapy
· Definitions for compression atelectasis, spontaneous pneumothorax, reabsorption atelectasis
· Who is at risk of developing ATX
· Causes of ATX in post operative patients
· CXR findings of ATX
· How do modes of lung expansion result in lung expansion
· Transpulmonary pressure gradient, how can it be increased
· Know indications/contraindications, use, goals, troubleshooting, hazards for:
· Incentive spirometer
· Pep devices
· CPAP
· **There will be no questions on IPPB, but review for your own knowledge
· Types of IS, teach IS preoperatively
· How do you know if a pt with ATX is improving?
· Explain instruction for a sustained maximal inspiration, how long should it last
· Diaphragmatic breathing
· Monitoring of IS, how many breaths, how often…
· Common cause for CPAP not to deliver set pressure
Ch. 44: Airway clearance therapy
· Know normal characteristics of a cough
· Compression
· Closure of glottis
· Deep breath
· Explusion using abdominal muscles
· What triggers coughing
· What is required to have a normal airway clearance
· What may provoke a cough?
· Consequences of having retained secretions/mucus plugs, partial or full obstructions
· Understand different causes for ineffective cough- weak inspiratory muscles, poor compression and so forth
· What impairs mucocilliary clearance in intubated patients
· Diseases that alter normal mucus clearance
· Causes of Bronchiectasis
· What effects the cough reflex
· Goals of airway clearance
· Amount of mucus produced a day expected amount after chest physical therapy
· What labs or assessments would be indicative for the need for airway clearance
· Airway clearance techniques and devices, know when to apply
· Postural drainage and percussion
· IS
· Positive airway pressure
· Contraindications to postural drainage
· Contraindications to turning patients
· How do you determine position of patient based on CXR
· Postural drainage: indications, signs of improvement with use, hazards, contraindications
· Use, indications, hazards of PEP, PAP, EPAP, CPAP…
· Huff coughing
· Oscillation / vest therapy, indications settings, use
· Flutter device, Acapella, EZPAP: indications, how the resistance works…
Ch. 45: Respiratory Failure
· How is respiratory failure diagnosed (look at FIO2, pH, PaO2, PaCO2…)
· Hypercapnic failure: Review causes
· Type I and Type II failure: Causes, treatments
· Hypoxemic failure: causes (V/Q mismatch, hypoventilation, shuting…)
· Shunting and V/Q mismatching
· Signs and symptoms of hypoxic failure, CXR appearance
· Mixed venous issues, commonest cause = Cardiac disease
· Normal A-a gradient on room air and with 100% O2
· Treatment for shunting
· Features of Gullian-Barre
· Chronic vs acute respiratory failure, how do you know someone has acute on chronic?
· WOB, signs and symptoms
· Indication to intubate, pH less than 7.2
· Parameters that indicate need to intubate: MIP, VT, VC, Ve, RR, VD/VT, A-a gradient
· Normal PF ratio
· Adequacy of alveolar ventilation
· Assessing muscle strength: FVC, MIP, MVV
· Contractile respiratory muscle fatigue
· Causes of increased WOB in intubated patients: ETT, vent circuit, Auto-PEEP
· What modes should be used for acute failure
· What mode is recommended for hypoxemic failure: CPAP
· Pressure control used with ARDS
· Greatest risk of Auto-peep = COPD
· Causes of dynamic hyperinflation (increased E-time, increased RAW, decreased exp flow)
· How do you reduce auto-peep
Ch. 46: Mechanical Ventilators
· Definition of ventilators
· Ventilator power source
· Equation of motion
· Definition of cycle, trigger, limit
· Patient vs machine trigger/cycle
· Trigger variables (pressure, flow, volume)
· Purpose of vent alarms
· Circuit compliance and resistance
· Volume control, pressure control, pressure regulated volume control breath types.
· Pressure support
· Trends, waveforms= use/purpose
· Spontaneous, assisted and controlled/mandatory breath
· Goals of mechanical ventilation
Ch. 47: Physiology of Ventilator support
· Spontaneous ventilation effects vs mandatory breathing
· **Note there will be no questions on negative pressure ventilation
· How does PPV work: Ppl pressure increases, Palv increases, alveolar pressure exceeds Ppl pressure
· Shunt: give PEEP, refractory to FIO2
· PEEP: Indications, How does it work, what does it do, how do we set it and what are the hazards
· Spont VT range: 5-7 ml/kg
· Mechanical volume range: 4-8ml/kg (restrictive 4-6 and normal 6-8)
· Rates: normally 10-20, set higher for met acidosis, ARDS, ICP (maybe), resp acidosis
· Compliance: Static vs dynamic, causes for increases/decreased, formula
· Consequence of decrease compliance
· Mean airway pressure: What can increase it (PEEP, I-time, Square to ramp waveform, PIP)
· During PC volume varies depending on: set pressure limit, patient lung mechanics, patient effort
· Know what occurs during pressure and volume ventilation
· Recruitment maneuvers
· Review modes: CPAP, CMV, IMV, PSV; when are they used, how do they work, which one would increase WOB the most
· Normal WOB: 0.6-0.9 J/L
· Plateau pressure: how is it obtained, what does it represent, what values do we try to keep it below (28 cmH2O)
· How does PEEP help with Auto-PEEP, and used with COPD
· Detrimental effects of PEEP
· Contraindications to use of PEEP
· Square vs ramp waveform
· What leads to patient ventilator asynchrony
· Why are patient turned every two hours on the vent
· What happens to PIP on VC when the RAW increases
· Causes for low volume on the vent
· What are time constants?
· Who would you use inverse ratios on
· What are the indications for APRV
· Pressure support: patient triggered, pressure limited, flow cycled
· Side effects/hazards of mechanical ventilation: decreased perfusion
Ch. 48: Patient ventilator interaction
· Causes of patient ventilator asynchrony:
· Trigger issues (poor sensitivity setting)
· Abnormal respiratory drives
· Auto-peep
· Flow asynchrony
· Change in clinical status
· Double triggering/short or long I-times
· Pain, anxiety
· Adverse effects of poor patient ventilator interaction
· How is auto-peep minimized
· How is flow asynchrony in volume ventilation corrected
· How deep should the ETT be on an adult male patient?
· How does the traches shift with severe pneumothorax
· What do you do if your patient becomes severely distressed and alarms are sounding
· Which modes cause the least asynchrony (PAV, NAVA)
· Which mode does asynchrony most commonly occur (VC)
· Auto-peep: How does it effect triggering, how do you correct it
· Normal trigger delay
· Causes of auto-triggering
Ch. 49: Initiating and adjusting invasive ventilation support
· Most common cause of acute respiratory failure requiring mechanical ventilation
· Calculation of Ve
· Calculation of VA
· Goals of mechanical vent support
· Hazards associated with the vent
· Advantages of Assist Control ventilation
· Advantages of pressure control ventilation
· Advantages of volume control ventilation
· VT ranges for normal and restrictive lungs
· How do you improve respiratory acidosis
· Low volumes, higher rates/higher PEEP= ARDS
· Vent order includes: Mode, FIO2, rate, VT, PEEP typically
· Know definition of AC
· Desired PaCO2 and PaO2 formulas
· Permissive hypercapnia: what is it, when do we do it
· Pressure support, when is it used, what does it do
· How do you decrease CO2 production on a patient
· Flow triggering
· Appropiate I:E ratios
· FIO2, what level do we use/start
· Pronning, use/indications
· Optimal peep
· When should you obtain an ABG after initiating the vent
· Alarm settings
Ch. 50: NIV
· Indications, contraindications for NIV
· Goals of NIV
· When do we use ST vs CPAP
· Correcting large air leaks
· Benefits of using CPAP and NIV
· Use of NIV for OSA, hypoventilation patients
· What occurs if you over tighten a mask
· Nasal vs face masks
· Hazards/side effects of being on NIV
· Settings, IPAP, EPAP, Rate, FIO2, Ramp, C-Flex
· IPAP – EPAP = Pressure support, used to correct CO2
· When do we add humidity
· Physiological effects of NIV
· When would you intubate a patient on NIV
· Most common complication with NIV