Immunology test 3

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Figure 8.1 Dendritic cells take up antigens at a site of wounding and infection in the skin and carry them to the draining lymph node for presentation to naive T cells.

T-cell circulation through a lymphoid tissue.

    

Fig. 8.4

Naive T cells encounter antigen during their circulation through peripheral lymphoid organs.

   

Fig. 8.3

Figure 8.13 Naive CD4 T cells that recognize self antigens are prevented from responding to those antigens.

Fig. 8.8

          

Fig. 8.10

            

Fig. 8.12

                      

Fig. 8.20

Shows an example of a CD8 effector T cell binding antigen at the site of infection.

Fig. 8.14

                       

Two types of C D 8 T cells as follows:

Cytotoxins Cytokines
Perforin Granzymes Granulysin Serglycin I F N – gamma L T I L – 2

C D 4 T cells are as follows:

T subscript H 1 cells T subscript H 2 cells T subscript F H cells T subscript H 17 cells T regulatory cells (T subscript reg)
Cytokines Cytokines Cytokines Cytokines Cytokines
I F N – gamma G M – C S F T N F – alpha L T I L – 2 I L – 4 I L – 5 I L – 10 I L – 13 T G F – Beta I L – 21 I l – 4 I F N – gamma I L – 17 I L – 21 I L – 22 I L – 26 T G F – beta I L – 10 I L - 35
Help macrophages to suppress intracellular infections Help basophils, mast cells, eosinophils, and B cells respond to parasite infections Help B cells become activated, switch isotype, and increase antibody affinity Enhance the neutrophil response to fungal and extracellular bacterial infections Suppress the activities of other effector T-cell populations

Fig. 8.21

                             

Fig. 8.27 – shows function of a CD4 T cell (TH1)

                              

Fig. 8.28 – shows function of a CD4 T cell (TFH)

Fig. 7.19 What happens if a self-reactive T cells are not negatively selected for apoptosis?

                       

Two types of C D 8 T cells as follows:

Cytotoxins Cytokines
Perforin Granzymes Granulysin Serglycin I F N – gamma L T I L – 2

C D 4 T cells are as follows:

T subscript H 1 cells T subscript H 2 cells T subscript F H cells T subscript H 17 cells T regulatory cells (T subscript reg)
Cytokines Cytokines Cytokines Cytokines Cytokines
I F N – gamma G M – C S F T N F – alpha L T I L – 2 I L – 4 I L – 5 I L – 10 I L – 13 T G F – Beta I L – 21 I l – 4 I F N – gamma I L – 17 I L – 21 I L – 22 I L – 26 T G F – beta I L – 10 I L - 35
Help macrophages to suppress intracellular infections Help basophils, mast cells, eosinophils, and B cells respond to parasite infections Help B cells become activated, switch isotype, and increase antibody affinity Enhance the neutrophil response to fungal and extracellular bacterial infections Suppress the activities of other effector T-cell populations

Fig. 8.21

                         

Fig. 8.23 – shows function of a CD8 T cell

                          

Fig. 8.24 – shows function of a CD8 T cell