Immunology test 3

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Figure 8.1 Dendritic cells take up antigens at a site of wounding and infection in the skin and carry them to the draining lymph node for presentation to naive T cells.

T-cell circulation through a lymphoid tissue.

Fig. 8.4

Naive T cells encounter antigen during their circulation through peripheral lymphoid organs.

Fig. 8.3

Figure 8.13 Naive CD4 T cells that recognize self antigens are prevented from responding to those antigens.

Fig. 8.8

Fig. 8.10

Fig. 8.12

Fig. 8.20

Shows an example of a CD8 effector T cell binding antigen at the site of infection.

Fig. 8.14

Two types of C D 8 T cells as follows:

Cytotoxins	Cytokines
Perforin Granzymes Granulysin Serglycin	I F N – gamma L T I L – 2

C D 4 T cells are as follows:

T subscript H 1 cells	T subscript H 2 cells	T subscript F H cells	T subscript H 17 cells	T regulatory cells (T subscript reg)
Cytokines	Cytokines	Cytokines	Cytokines	Cytokines
I F N – gamma G M – C S F T N F – alpha L T I L – 2	I L – 4 I L – 5 I L – 10 I L – 13 T G F – Beta	I L – 21 I l – 4 I F N – gamma	I L – 17 I L – 21 I L – 22 I L – 26	T G F – beta I L – 10 I L - 35
Help macrophages to suppress intracellular infections	Help basophils, mast cells, eosinophils, and B cells respond to parasite infections	Help B cells become activated, switch isotype, and increase antibody affinity	Enhance the neutrophil response to fungal and extracellular bacterial infections	Suppress the activities of other effector T-cell populations

Fig. 8.21

Fig. 8.27 – shows function of a CD4 T cell (TH1)

Fig. 8.28 – shows function of a CD4 T cell (TFH)

Fig. 7.19 What happens if a self-reactive T cells are not negatively selected for apoptosis?

Two types of C D 8 T cells as follows:

Cytotoxins	Cytokines
Perforin Granzymes Granulysin Serglycin	I F N – gamma L T I L – 2

C D 4 T cells are as follows:

T subscript H 1 cells	T subscript H 2 cells	T subscript F H cells	T subscript H 17 cells	T regulatory cells (T subscript reg)
Cytokines	Cytokines	Cytokines	Cytokines	Cytokines
I F N – gamma G M – C S F T N F – alpha L T I L – 2	I L – 4 I L – 5 I L – 10 I L – 13 T G F – Beta	I L – 21 I l – 4 I F N – gamma	I L – 17 I L – 21 I L – 22 I L – 26	T G F – beta I L – 10 I L - 35
Help macrophages to suppress intracellular infections	Help basophils, mast cells, eosinophils, and B cells respond to parasite infections	Help B cells become activated, switch isotype, and increase antibody affinity	Enhance the neutrophil response to fungal and extracellular bacterial infections	Suppress the activities of other effector T-cell populations

Fig. 8.21

Fig. 8.23 – shows function of a CD8 T cell

Fig. 8.24 – shows function of a CD8 T cell