Organ Transplant Argument Paper

5/13/2019

Jennifer Kubach

Organ Transplant

More funding should be spent on the creation of artificial organs, like 3-D bioprinting, using stem cells to grow the organs in a lab and artificial pumps.

3-D Bioprinting

3-D bioprinting has a great potential to solve the increasing global organ shortage that we face in the healthcare field.

· Bioprinting could replace organ donors

· This technology has the potential to replace organ donors by printing human organs on demand eliminating the need for living or deceased human donation.

· Advance Drug Delivery Reviews

· Bioprinting is an additive manufacturing process where biomaterials such as cells and growth factors are combined to create tissue-like structures that imitate natural tissues.

· The greatest importance of bioprinting lies in the resulting tissue-like structures that mimic the actual micro- and macro-environment of human tissues and organs.

· Advance Drug Delivery Reviews

· The materials and scientific precision required to successfully print an organ is very expensive.

· In the last five to ten years the 3D printing industry has increased to $100 million-dollar price range making certain bioprinting unavailable to the general population and creating a social economically ranking out of waiting lists.

· Organ U.s Organ and Tissue Transplant Cost Estimate and Discussion

Lab Grown Organs

The ability to bio engineer organs can solve the long waitlists for organ transplants and the risk of an organ transplant being rejected.

· Researchers have been working on ways to grow healthy organs outside the human body.

· One such method, called blastocyst complementation, has already produced promising results. Researchers take blastocysts, the clusters of cells formed several days after egg fertilization, from mutant animals missing specific organs and inject them with stem cells from a normal donor, the new organ retains the characteristics of the original stem cell donor and can thus potentially be used in transplantation therapy.

· Growing Human Organs

· When the stem cells are used in growing organs and they come from the patient the risk of the body rejecting it can be eliminated.

· Other benefits of to lab grown organs are patients don’t wait for a suitable donor allowing them to have surgery earlier.

· The Chemical Engineer

· Advances in stem cell technology can ensure that each organ would be a genetic match for its recipient.

· It could take only months to generate, alleviating the current desperate need for organ donors and subsequent lifelong

· The Chemical Engineer

External Devices

Currently there are treatments for some types of end stage disease that replace the function of failing organs like artificial hearts, LVADs, and ICDs.

· Artificial hearts are sometimes referred to a bridge to transplant, meaning that any organ or surrogate device used to stabilize a patient before definitive transplantation of a matched organ.

· Estimates of the cost of the artificial heart include charges for the surgical procedure, device and console, and continuing medical surveillance. These estimates range from a low of $100,000 to a high of $300,000 per patient in the initial year.

· Living with Devices

· Left ventricle assist devices is a mechanical pump-type device that is surgically implanted to help maintain the pumping ability of a heart that is unable to effectively function on its own.

These mechanical heart pumps can significantly improve a patient’s health and survival rate.

· Living with Devices

· Hemodialysis is the most common method used to treat advanced and permanent kidney failure.

· Kidney patients die prematurely in the United States each year, and about 100 000 more suffer the debilitating effects of dialysis, because of a shortage of transplant kidneys. To reduce this shortage, many advocates having the government compensate kidney donors.

· Living with Devices

References

· The sources that I found are appropriate because one was from the university’s library database and the other source contained vital information for my argument.

· Sanjair, V., Wei Cheng, Y., Wen Feng, L., Jerry Ying His Fuh (2018, July). 3D bioprinting of tissues and organs for regenerative medicine. Advanced Drug Delivery Reviews, 132(0169-409X), 296-332.

·

· This reference is appropriate for getting my point across because it comes from a trusted source and it is also peer reviewed, relevant to one of my arguments and it is current information

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