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Module 10 LO3

Nervous System Cells

Dr. Lisa Brinn [email protected]

3. Nervous System Cells

A. Neurons B. Neuroglia

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A. Structure of Typical Neuron

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Structural Classification of Neurons

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Two Examples of CNS Neurons

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Pyramidal cell of cerebral cortex

Purkinje cell of cerebellar cortex

B. Neuroglias

a) Central Nervous System • Astrocytes • Oligodendrocytes • Ependymal cells • Microglias

b) Peripheral Nervous System • Schwann cells • Satellite cells

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a) Neuroglia of CNS

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Astrocytes • Largest and most numerous • Star-shaped cells • Astrocyte processes make contact with:

• Blood capillaries • Neurons • Pia mater

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Functions of Astrocytes

• Provide strength • Maintains unique permeability characteristics of

endothelial cells • In embryo: secrete chemicals that appear to regulate:

• growth, migration, and interconnections

• Maintains appropriate chemical environment for generation of nerve impulses

• Play a role in learning and memory by influencing formation of neural synapses

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Oligodendrocytes • Processes - responsible for forming myelin sheath

• insulates axon and increases speed of nerve impulse conduction

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Microglial Cells or Microglia

• Small cells with slender processes • Originate from red bone marrow

• function as phagocytes

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Ependymal Cells • Cuboidal to columnar cells • Line ventricles of brain and central canal of spinal cord • Functionally:

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• produce, possibly monitor, and assist in circulation of cerebrospinal fluid

• Form blood–cerebrospinal fluid barrier

b) Neuroglia of PNS

a) Schwann cells b) Satellite cells

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Myelinated and Unmyelinated Axons

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