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Medication.  A metallic sensation is perhaps the most common taste quality reported and is often attributed to medication use. More than 200 medications are known to cause taste disorders, yet this side effect is often overlooked in drug development, an article in  Toxicological Sciences  states. Cancer treatment.  Dysgeusia can occur as a side effect of chemotherapy and radiation. It is more common in the treatment of head and neck cancers, though it can appear with treatment of any type of cancer. According to the  Society of Sensory Professionals , cancer treatment can interfere with the ability to taste or smell food temporarily or permanently. Doctors should address these effects to prevent malnutrition and weight loss. Diabetes.  Another instance of tongue dysfunction is in people with undiagnosed diabetes, especially in cases of adult onset or type 2 diabetes mellitus. Referred to as "diabetic tongue" by an article in the  Journal of Family Medicine and Primary Care , dysgeusia can be an early symptom of the disease. Researchers found altered taste was not constant throughout the day, so it could be attributed to fluctuations in blood sugar levels and identified as an early clinical sign for diabetes. Other causes.  The previous study also recognized that other systemic health problems, such as zinc deficiencies,  dry mouth  and autoimmune diseases could also cause the taste changes. Other causes range from aging and physiological changes, such as pregnancy and menopause. In addition, head injuries and certain surgeries of the ear, nose and throat can cause taste disorders. Dental issues like poor oral hygiene and the extraction of a wisdom tooth can also lead to dysgeusia. 13