Skin

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Chapter_16_LO.ppt

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Chapter 16
Skin

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Learning Objectives

  • Name the layers of the skin and the accessory structures associated with the skin.
  • Build medical words using the combining forms that are related to the specialty of dermatology.
  • Identify lesions, sign and symptoms, and pathologic conditions that relate to the skin.

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Learning Objectives (cont’d)

  • Describe laboratory tests and clinical procedures that pertain to the skin and recognize relevant abbreviations.
  • Apply your new knowledge to understanding medical terms in their proper contexts, such as medical reports and records.

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Chapter 16
Lesson 16.1

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INTRODUCTION

Skin: Integumentary system

  • weighs 8-10 lbs.
  • covers 22 sq. ft. in average adult

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  • What tissues can you predict will be integrated into this organ system?
  • What are the unique qualities of epithelium that make it a suitable tissue for covering the body?
  • How is the epithelium on the “outside” (part of the skin) similar to that on the inside of the body?

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Functions of Skin

  • Provides protective membrane
  • Skin glands lubricate and cool the skin
  • Receptor for sensations
  • Helps Maintain body temperature

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  • Have students define desiccation. Ask them to list three ways that skin guards against desiccation.
  • How does skin guard against acidic secretions?

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Functions of Skin (cont’d)

Produces sweat: sweat glands produce watery secretion that evaporates and cools

Produces sebum: sebaceous glands produce oily secretion that lubricates skin and hair

Receives sensation: pain, temperature, pressure, and touch

Thermoregulates: interprets message from heat center in the brain

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  • Ask the students to define the word thermoregulate. How does the skin thermoregulate?
  • There are multiple mechanisms for thermal control. Describe at least three or four.

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STRUCTURE OF THE SKIN

Epidermis: outermost, thin cellular membrane

Dermis: next layer; dense fibrous, connective tissue

Subcutaneous tissue (hypodermis): thick, fat-containing tissue

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  • What does the epidermis lack? Ask the students to describe what it is dependent upon.
  • What is the dermis composed of? Ask the students to describe what supports this layer.
  • Ask the students what lipocytes are and where they are found.

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Structure of the Skin (cont’d)

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  • In the inset of this picture (B) you can see what are called dermal papillae. They look like wavy folds. What is the advantage of this kind of tissue architecture?
  • The dermis appears to be pushing up folds into the epidermis. Why?
  • Is the epithelium vascular? Why is that an advantage or disadvantage?

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Structure of the Skin (cont’d)

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  • In the inset of this picture (B) you can see what are called dermal papillae. They look like wavy folds. What is the advantage of this kind of tissue architecture?
  • The dermis appears to be pushing up folds into the epidermis. Why?
  • Is the epithelium vascular? Why is that an advantage or disadvantage?

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HAIR: cells filled with the hard protein;

keratin

  • Hair follicles: shafts that hold the hair
  • Five million hairs on body; 100,000 on head
  • Melanocytes at the root form the color
  • Grow 0.5 inch (1.3 cm) per month
  • Cutting does not affect growth

ACCESSORY ORGANS
OF THE SKIN

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  • Ask the students to describe melanocytes and where they can be found.
  • What functions does hair have? (sensory, thermoregulation)

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ACCESSORY ORGANS
OF THE SKIN

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Accessory Organs of Skin (cont’d)

NAILS: hard keratin plates covering toes and fingers

  • lunula
  • cuticle
  • paronychium

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  • How are hair, nails, and epidermis alike?
  • How do these structures grow and slough off cells?

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Accessory Organs of Skin (cont’d)

GLANDS: Sebaceous and Sweat

  • Sebaceous glands secrete oily sebum into hair follicle to lubricate
  • Sweat glands secrete into pores to moisten and cool
  • Both subject to bacterial growth

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  • Why do people have so many sweat glands?
  • Could people live without sweat glands?
  • Do sebaceous glands make hair feel oily?

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Accessory Organs of Skin (cont’d)

Sebaceous gland

Sweat glands: eccrine sweat gland, and apocrine sweat gland.

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  • Why do people have so many sweat glands?
  • Could people live without sweat glands?
  • Do sebaceous glands make hair feel oily?

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COMBINING FORMS
AND TERMINOLOGY

COMBINING FORMS

  • adip/o fat
  • albin/o white
  • caus/o burn, burning
  • cauter/o heat, burn
  • cutane/o skin
  • derm/o skin

Combining Form Meaning

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COMBINING FORMS

  • dermat/o skin
  • diaphor/o profuse sweating
  • erythem/o redness
  • erythemat/o redness
  • hidr/o sweat
  • ichthy/o scaly, dry

Combining Form Meaning

COMBINING FORMS
AND TERMINOLOGY

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COMBINING FORMS

  • kerat/o hard, horny tissue
  • leuk/o white
  • lip/o fat
  • melan/o black
  • myc/o fungus
  • onych/o nail

Combining Form Meaning

COMBINING FORMS
AND TERMINOLOGY

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COMBINING FORMS

  • phyt/o plant
  • pil/o hair, hair follicle
  • py/o pus
  • rhythid/o wrinkle
  • seb/o sebum
  • squam/o scale-like

Combining Form Meaning

COMBINING FORMS
AND TERMINOLOGY

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COMBINING FORMS

  • steat/o fat
  • trich/o hair
  • ungu/o nail
  • xanth/o yellow
  • xer/o dry

Combining Form Meaning

COMBINING FORMS
AND TERMINOLOGY

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COLORS

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  • Why do people have so many sweat glands?
  • Could people live without sweat glands?
  • Do sebaceous glands make hair feel oily?

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QUICK QUIZ:

Which combining form refers to white?

chlor/o

jaund/o

melan/o

albin/o

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CORRECT Answer is D, albin/o means white as in albinism

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QUICK QUIZ:

Which combining form refers to the same color as jaund/o?

xanth/o

chlor/o

erythr/o

cyan/o

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CORRECT Answer is A, xanth/o means yellow as in xanthoma See page 632 for table referencing colors.

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Chapter 16
Lesson 16.2

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Cutaneous
Lesions

LABEL the following lesions:

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  • What is the definition of a lesion?
  • Which of these lesions are similar but are differentiated by size?
  • Which lesions involve the dermis layer?

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REVIEW the following lesions:

Cutaneous
Lesions

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  • What is the definition of a lesion?
  • Which of these lesions are similar but are differentiated by size?
  • Which lesions involve the dermis layer?

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Signs and Symptoms

Alopecia:

absence of hair where it normally grows

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  • What are some causes of alopecia?
  • Are there any treatments for baldness? Are they successful?
  • Another form of alopecia is a result of trichotillomania, or obsessive hair-pulling.

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Signs and Symptoms (cont’d.)

Ecchymosis: blue-black marks on the skin

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  • What can cause ecchymosis?
  • What is the treatment?

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Petechia: small pinpoint hemorrhage

Signs and Symptoms (cont’d.)

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  • Use the pictures as examples. Ask students whether they have ever been diagnosed with any of the skin conditions mentioned.
  • What diseases are associated with these symptoms?
  • What is pruritus?
  • What is purpura?

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Urticaria: acute allergic reaction with red, round wheals on skin

Signs and Symptoms (cont’d.)

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  • What is the common term for urticaria?
  • Have students discuss their experiences (or that of someone they know) with hives.
  • What causes hives? How long do they last?

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Abnormal Conditions

Acne: papular and pustular eruption of skin with increased production of sebum

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  • What is the medical term for a blackhead?
  • Why are adolescents so prone to acne? Myths and reality.
  • Are over-the-counter treatments effective?

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Burns: injury to tissue due to heat, chemical, electric shock, lightning or radiation. Image shows (A), Second degree burn and (B) shows Third degree burn.

Abnormal Conditions (cont’d.)

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  • Go over the different degrees of burns and use a chart with the layers of the skin to demonstrate how deep the burns go.
  • What percentage of body burn results in death? Why?

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Abnormal Conditions (cont’d.)

  • Cellulitis: diffuse acute infection of skin
  • Eczema: inflammation of skin with erythematous and papulovesicular lesions caused by allergy
  • Exanthematous viral diseases: rash due to virus (e.g. rubella)
  • Gangrene: death of tissue with loss of blood supply

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  • Which of these diseases is/are common in children? Why?
  • What are other diseases that are similar to eczema? Are they all treated in the same way?

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Abnormal Conditions (cont’d.)

  • Impetigo: contagious pyoderma caused by staph or strep
  • Psoriasis: chronic recurrent dermatosis with silver gray scales that itch
  • Scabies: parasitic (tiny mites) and infectious pruritus
  • Scleroderma: chronic and progressive disease of skin with hardening of connective tissue

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  • Which of these diseases are NOT contagious?
  • Which disease may worsen if the patient experiences anxiety?

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Abnormal Conditions (cont’d.)

  • Systemic lupus erythematosus (SLE): inflammatory disease of collagen in skin, joints, and internal organs

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  • What are the current thoughts about the origin of SLE? How is it treated?
  • Where have we discussed it before because of other organ systems it affects?

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Abnormal Conditions (cont’d.)

Tinea corporis

Tinea unguium

Tinea—infection of the skin caused by fungus.

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  • What is tinea? (fungal infection of skin or nails i.e. ringworm, athlete’s foot)
  • What is vitiligo? (loss of pigment in areas of skin causing milk-white patches)

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Abnormal Conditions (cont’d.)

vitiligo

Vitiligo—Loss of pigment in areas of skin.

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  • What is tinea? (fungal infection of skin or nails i.e. ringworm, athlete’s foot)
  • What is vitiligo? (loss of pigment in areas of skin causing milk-white patches)

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Chapter 16
Lesson 16.3

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Skin Neoplasms (Benign)

Callus

Keloid

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  • What is a callus? (increased growth of cells in keratin layer of epidermis due to friction against skin)
  • What is a keloid? (hypertrophied, thickened scar after trauma or surgery)
  • Ask for student examples of places that commonly develop calluses. Why?
  • Some people who are prone to keloids are discouraged from having their ears pierced.

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Skin Neoplasms (Benign) (cont’d.)

  • Keratosis: thickened area of epidermis
  • Leukoplakia: white thickened patches on tongue or cheek
  • Nevus: pigmented lesion
  • Verruca: warts caused by virus

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  • Have students find images for abnormalities not shown in the text. Images are very useful for remembering these conditions.

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Skin Neoplasms (Cancerous)

Basal cell carcinoma

Malignant tumor of the basal cell layer of the epidermis

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  • Refer back to the chapter that included AIDS.
  • Why are AIDS patients susceptible to this condition?
  • Why does it rarely occur in the rest of the population?

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Skin Neoplasms (Cancerous)

Malignant tumor of the squamous epithelial cells of the epidermis.

Squamous cell carcinoma

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  • Refer back to the chapter that included AIDS.
  • Why are AIDS patients susceptible to this condition?
  • Why does it rarely occur in the rest of the population?

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The ABCDEs of malignant melanoma.

A. Asymmetry

B. Border, irregular or circumscribed

D. Diameter, usually larger than 6mm

C. Color variation

Skin Neoplasms (Cancerous) (cont’d.)

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  • These skin tumors often metastasize to the lung, liver, bone, and brain. What is the current treatment for this type of cancer?
  • Squamous cells can grow wherever there is squamous epithelium (internal or external). Common places include the mouth, larynx, bladder, esophagus, and lungs. Some are cigarette-related.
  • Why are healthy organs lined with squamous cells in the first place? What about this tissue makes it appropriate for those particular organ systems?

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Skin Neoplasms (Cancerous)

Malignant, vascular, neoplastic growth characterized by cutaneous nodules.

Kaposi sarcoma

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  • Refer back to the chapter that included AIDS.
  • Why are AIDS patients susceptible to this condition?
  • Why does it rarely occur in the rest of the population?

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Laboratory Tests

Bacterial analyses: pus or fluid

samples examined to detect

microorganisms

Fungal tests: scrapings for culture and

microscopic examination after

treatment with KOH.

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Clinical Procedures

Cryosurgery: destroy tissue with

subzero temperatures using liquid

nitrogen

Curettage: scrape lesion with sharp

curet

Electrodesiccation: destroy tissue by

burning with electric spark

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  • For what conditions is electrodesiccation recommended?

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Clinical Procedures (cont’d.)

Mohs surgery: remove thin layers of

growth to examine under microscope

(basal and squamous cell)

Skin biopsy: punch and shave to

remove for examination in path lab

Skin test: test reaction of body to

allergen with skin test (scratch or patch tests)

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  • Discuss how some of the surgeries are for both diagnosis and treatment. Removal is done whether or not the physician knows that the lesion is cancerous.
  • All suspicious-looking tissues removed from the body are sent to the pathology lab for analysis. Why?

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  • ABCDE asymmetry, border, color, diameter, evolution — characteristics associated with skin cancer.
  • bx biopsy
  • DLE discoid lupus erythematosus
  • PPD purified protein derivative
  • SLE systemic lupus erythematosus
  • SC subcutaneous

Abbreviations

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  • Ask students to provide the full terms for these abbreviations.

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REVIEW SHEET

COMBINING FORMS

  • adip/o ___________
  • albin/o ___________
  • caus/o ___________
  • cauter/o ___________
  • cutane/o ___________
  • derm/o ___________

Combining Form Meaning

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COMBINING FORMS

  • adip/o fat
  • albin/o white
  • caus/o burn, burning
  • cauter/o heat, burn
  • cutane/o skin
  • derm/o skin

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • dermat/o ___________
  • diaphor/o ___________
  • erythem/o ___________
  • erythemat/o ___________
  • hidr/o ___________
  • ichthy/o ___________

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • dermat/o skin
  • diaphor/o profuse sweating
  • erythem/o redness
  • erythemat/o redness
  • hidr/o sweat
  • ichthy/o scaly, dry

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • kerat/o ___________
  • leuk/o ___________
  • lip/o ___________
  • melan/o ___________
  • myc/o ___________
  • onych/o ___________

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • kerat/o hard, horny tissue
  • leuk/o white
  • lip/o fat
  • melan/o black
  • myc/o fungus
  • onych/o nail

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • phyt/o ___________
  • pil/o ___________
  • py/o ___________
  • rhythid/o ___________
  • seb/o ___________
  • sabace/o ___________
  • squam/o ___________

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • phyt/o plant
  • pil/o hair, hair follicle
  • py/o pus
  • rhythid/o wrinkle
  • seb/o sebum
  • squam/o scale-like

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • steat/o ___________
  • trich/o ___________
  • ungu/o ___________
  • xanth/o ___________
  • xer/o ___________

Combining Form Meaning

REVIEW SHEET

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COMBINING FORMS

  • steat/o fat
  • trich/o hair
  • ungu/o nail
  • xanth/o yellow
  • xer/o dry

Combining Form Meaning

REVIEW SHEET

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SUFFIXES

  • -algia ___________
  • -derma ___________
  • -esis ___________
  • -lysis ___________
  • -ose ___________

Suffix Meaning

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SUFFIXES

  • -algia pain
  • -derma skin
  • -esis condition
  • -lysis breakdown; separation; destruction; loosening
  • -ose full of; pertaining to; sugar

Suffix Meaning

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SUFFIXES

  • -osis ___________
  • -ous ___________
  • -plakia ___________
  • -plasty ___________
  • -rrhea ___________

Suffix Meaning

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SUFFIXES

  • -osis condition, usually abnormal
  • -ous pertaining to
  • -plakia plaque
  • -plasty surgical repair
  • -rrhea flow; discharge

Suffix Meaning

REVIEW SHEET

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