abnormal spychology
Essentials of Abnormal Psychology
Eighth Edition
Chapter 3
Clinical Assessment, Diagnosis and Research in Psychopathology
© 2019 Cengage. All rights reserved.
© 2019 Cengage. All rights reserved.
1
Outline
Assessing Psychological Disorders
Diagnosing Psychological Disorders
Research in Psychopathology
Types of research methods
Genetic and Cultural Research
Research Ethics
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Focus Questions
What are clinical assessment and diagnosis?
What are the basic components and methods of psychopathology research?
How do researchers study the role of genetics? How do researchers study behavior across time and culture?
Why are ethical principles important in research?
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Assessing Psychological Disorders, Part 1
Purposes of clinical assessment
To understand the individual
To predict behavior
To plan treatment
To evaluate treatment outcome
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Assessing Psychological Disorders, Part 2
Analogous to a funnel
Starts broad
Multidimensional in approach
Narrow to specific problem areas
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Key Concepts in Assessment, Part 1
Reliability
Consistency in measurement
Examples include test-retest and inter-rater reliability
Validity
What an assessment measures and how well it does so
Examples include concurrent, discriminant, and predictive validity
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Reliability - degree to which a measure is consistent
Inter-rater reliability- consistency across two or more raters (e.g., do different therapists watching the same video agree that the patient is depressed?)
Test-retest reliability - consistency across time
Example of validity question: Are people who get higher scores on a measure of anxiety actually more anxious?
Key Concepts in Assessment, Part 2
Standardization
Ensures consistency in the use of a technique
Provides population benchmarks for comparison
Examples include structured administration, scoring, and evaluation procedures
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Concepts That Determine the Value of Clinical Assessments
FIGURE 3.1 Concepts that determine the value of clinical assessments.
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© 2019 Cengage. All rights reserved.
FIGURE 3.1 Concepts that determine the value of clinical assessments.
The Clinical Interview and Physical Exam, Part 1
Clinical interview
Most common clinical assessment method
Structured or semistructured
Example of semistructured interview: Anxiety Disorders Interview Schedule for DSM-5 (ADIS-5) has modules pertaining to anxiety, mood, and related disorders, designed to assess DSM-5 criteria
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Teaching tip: Some definitions.
Structured = you ask the exact same questions in the same order
Semi-structured (most common) Have an outline of questions that are followed, but some flexibility to ask more or less about certain areas depending on the needs of the interviewee
Clinical interviews may range from half an hour to 4+ hours depending on the needs of the patient and the purpose of the assessment. Longer assessments are necessary for some research studies and when you are trying to get a complete psychological history (e.g. previous diagnoses as well as current).
The Clinical Interview and Physical Exam, Part 2
Mental status exam
Appearance and behavior
Thought processes
Mood and affect
Intellectual functioning
Sensorium
Physical exam
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“Sensorium” = the patient’s general orientation. E.g. do they know where they are and what they’re doing?
Physical exams are often the “first pit stop” in assessing mental health, because many patients visit a primary care physician first. For example, a doctor might ascertain whether panic attacks are the result of a heart or respiratory condition, or whether depression could be due to the side effects of a medication. Physical exams are not typically conducted in outpatient clinics. They are more common in inpatient or hospital settings, or in the case of mental illnesses that are likely to affect physical functioning (e.g., substance use disorders, eating disorders, somatic symptom disorders, disorders in which a patient is taking meds with a lot of side effects, e.g., schizophrenia).
Components of Mental Status Exam
Subsequent focus—possible existence of disorder characterized by intrusive, unwanted thoughts, and resistance to them.
| Mental Status Exam | Frank |
| Appearance and behavior Over Behaviour Attire Appearance, posture, expressions | Persistent twitch Appearance appropriate |
| 2. Thought Rate of speech Continuity of speech Content of speech | Flow and content of speech reasonable |
| 3. Mood and affect Predominant feeling state of the individual says | Anxious mood Affect appropriate |
| 4. Intellectual functioning Type of vocabulary Use of abstractions and metaphors | Intelligence within normal limits |
| 5. Sensorium Awareness of surroundings in terms of person (self and clinician), time, and place – “oriented times three” | Oriented times three |
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© 2019 Cengage. All rights reserved.
FIGURE 3.2 Components of the mental status exam.
Behavioral Assessment and Observation, Part 1
Behavioral assessment
Focus on the present—here and now
Direct observation of behavior-environment relations
Purpose is to identify problematic behaviors and situations
ABCs—identify antecedents, behaviors, and consequences
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Behavioral Assessment and Observation, Part 2
Behavioral observation and behavioral assessment
Can be either formal or informal
Self-monitoring vs. being observed by others
Problem of reactivity using direct observation
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Reactivity = when your behavior is being observed (by yourself or someone else), it starts to change
ABCs of Observation
FIGURE 3.3 The ABCs of observation.
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© 2019 Cengage. All rights reserved.
FIGURE 3.3 The ABCs of observation.
Psychological Testing: Projective Tests, Part 1
Psychological testing
Must be reliable and valid
Projective tests
Rooted in psychoanalytic tradition
Used to assess unconscious processes
Project aspects of personality onto ambiguous test stimuli
Require high degree of inference in scoring and interpretation
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Technology Tip: This APA web site contains information and useful links related to psychological testing, including the ethics of testing. http://www.apa.org/science/testing.html
Psychological Testing: Projective Tests, Part 2
Examples
The Rorschach inkblot test; Thematic Apperception Test
Reliability and validity data tend to be mixed
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TAT = You see an ambiguous picture and tell a story about it.
The idea of projective tests is that when you’re presented with ambiguous stimuli, the way you interpret them says something about your personality
Rorschach Inkblot
FIGURE 3.4 This inkblot resembles the ambiguous figures presented in the Rorschach test.
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© 2019 Cengage. All rights reserved.
FIGURE 3.4 This inkblot resembles the ambiguous figures presented in the Rorschach test.
Objective Tests and Personality Tests
Objective tests
Roots in empirical tradition
Test stimuli are less ambiguous
Require minimal clinical inference in scoring and interpretation
Personality tests
Minnesota multiphasic personality inventory (MMPI)
Extensive reliability, validity, and normative database
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Technology Tip: Visit Dr. James Butcher’s MMPI Research Project website at the University of Minnesota for more information about the MMPI and its various incarnations: http://www1.umn.edu/mmpi/
Ch. 3 of the textbook has an extensive and interesting discussion of the MMPI.
Psychological Testing and Objective Tests
Intelligence tests
Nature of intellectual functioning and IQ
Originally developed as a measure of degree to which children’s performance diverged from others in their grade
The deviation IQ
Compare a person’s scores against those of other people who are of the same age
Verbal and performance domains
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Technology Tip: A site containing historical information related to intelligence testing: http://www.intelltheory.com/
Neuropsychological Testing, Part 1
Purpose and goals
Assess broad range of skills and abilities
Goal is to understand brain-behavior relations
Examples
The Luria-Nebraska and Halstead-Reitan batteries
Designed to assess for brain damage
Test diverse skills ranging from grip strength to sound recognition, attention, concentration
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Technology Tip: This site contains information and links about neuropsychology and neuropsychological assessment: http://www.neuropsychologycentral.com/index.html
Neuropsychological Testing, Part 2
Problems with neuropsychological tests
False positives: Mistakenly shows a problem where there is none
False negatives: Fails to detect a problem that is present
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Neuroimaging and Brain Structure, Part 1
Neuroimaging: pictures of the brain
Two objectives
Understand brain structure
Understand brain function
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Technology Tip: This site contains a series of excellent links to resources related to neuroimaging, neuroanatomy, and their relation to psychopathology: http://www.neuropsychologycentral.com/interface/content/links/page_material/imaging/imaging_links.html#a
Neuroimaging and Brain Structure, Part 2
Imaging brain structure
Computerized axial tomography (CAT or CT scan)
Utilizes X-rays
Magnetic resonance imaging (MRI)
Utilizes strong magnetic fields
Better resolution than CT scan
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Neuroimaging and Brain Function
Imaging brain function
Positron emission tomography (PET)
Single photon emission computed tomography (SPECT)
Both involve injection of radioactive isotopes
Isotopes react with oxygen, blood, and glucose in the brain
Functional MRI (fMRI)—brief changes in brain activity
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Psychophysiological Assessment, Part 1
Psychophysiological assessment
Assess brain structure, function, and activity of the nervous system
Psychophysiological assessment domains
Electroencephalogram (EEG)—brain wave activity.
ERP—Event-related potentials = brain response to a specific experience (e.g., hearing a tone)
Heart rate and respiration—cardiorespiratory activity
Electrodermal response and levels—sweat gland activity
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EEG = Electroencephalogram
Alpha waves – awake, resting patterns
Delta waves – asleep, relaxed patterns
Panic attacks – delta wave activity during wakefulness may indicate localized dysfunction
Psychophysiological Assessment, Part 2
Uses of routine psychophysiological assessment
Disorders involving a strong physiological component
Examples
PTSD, sexual dysfunctions, sleep disorders
Headache and hypertension
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Diagnosing Psychological Disorders: Foundations in Classification, Part 1
Diagnostic classification
Classification is central to all sciences
Assignment to categories based on shared attributes or relations
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Diagnosing Psychological Disorders: Foundations in Classification, Part 2
Idiographic strategy
What is unique about an individual’s personality, cultural background, or circumstances
Nomothetic strategy
Often used when identifying a specific psychological disorder, to make a diagnosis
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Idiographic – determination of individual, unique features or attributes
Nomothetic – determination of general classes and common attributes – involves the study of large groups with shared features
Diagnosing Psychological Disorders: Foundations in Classification, Part 3
Terminology of classification systems
Taxonomy—classification in a scientific context
Nosology—taxonomy in psychological/medical phenomena
Nomenclature—labels in a nosological system (e.g., “panic disorder” “depressive disorders”)
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Taxonomy – Classification in a scientific context
Nosology – Taxonomy in psychological / medical contexts
Nomenclature – Nosological labels (e.g., panic disorder)
Issues with Classifying and Diagnosing Psychological Disorders, Part 1
Categorical and dimensional approaches
Classical (or pure) categorical approach—strict categories (e.g., you either have social anxiety disorder or you don’t)
Dimensional approach—classification along dimensions (e.g., different people have varying amounts of anxiety in social situations)
Prototypical approach—combines classical and dimensional views
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Prototypical approach - categorical approach that combines features of the other approaches. Identifies essential features of a psychological disorder so that it can be classified, but allows for nonessential variations that do not necessarily change the classification (e.g., there are several ways one could meet criteria for major depression or panic disorder, but still get the diagnosis). The DSM-5 is based on this approach.
Issues with Classifying and Diagnosing Psychological Disorders, Part 2
Widely used classification systems
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Updated every 10–20 years
Current edition (released May 2013): DSM-5
Previous edition called DSM-IV-TR
ICD-10
International Classification of Diseases (ICD-10)
Published by the World Health Organization (WHO)
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History of the DSM, Part 1
Prior to 1980, diagnoses were made based on biological or psychoanalytic theory
Introduction of DSM-III in 1980 revolutionized classification
Classification newly relied on specific lists of symptoms, improving reliability and validity
Diagnoses classified along five “axes” describing types of problems (e.g., disorder categories, health problems, life stressors)
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Previously, psychopathology was categorized along five axes. Axis I = Clinical syndromes (most psychological disorders). Axis II = personality disorders and mental retardation (more pervasive), Axis III = relevant medical conditions. Axis IV = Relevant life stressors. Axis V = Global assessment of functioning (0-100 rating). DSM-5 no longer uses the axis system. This information is still taken into account by clinicians, but it’s not discussed in terms of axes.
History of the DSM, Part 2
DSM-IV introduced in 1994
Eliminated previous distinction between psychological vs. organic mental disorders
Reflected appreciation that all disorders are influenced by both psychological and biological factors
DSM-IV-TR (“text revision” of DSM-IV) incorporated new research and slightly altered criteria accordingly
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The DSM-5
Basic characteristics
Removed axial system
Clear inclusion and exclusion criteria for disorders
Disorders are categorized under broad headings
Empirically grounded, prototypic approach to classification
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DSM-5 represented some changes to classification. One major change is that the Axis system used in DSM-IV-TR was eliminated.
For a detailed outline of all changes in DSM-5, see Boettcher et al. 2013 – A Student’s Guide to Important Changes in DSM-5, part of the instructor resources for Barlow/Durand Abnormal Psychology and Durand/Barlow Essentials of Abnormal Psychology.
Unresolved Issues in DSM-5, Part 1
The problem of comorbidity
Defined as two or more disorders for the same person
High comorbidity is extremely common
Emphasizes reliability, maybe at the expense of validity (i.e., may artificially “split” diagnoses that are very similar)
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Discussion Tip: Have students discuss how these problems have changed over time and across diagnoses. Are there differences within this culture in terms of demographic factors (i.e., SES, ethnicity, geography, age)?
Unresolved Issues in DSM-5, Part 2
Dimensional classification
DSM was intended to move toward a more dimensional approach, but critics say it does not improve much from DSM-IV
Labeling issues and stigmatization
Some labels have negative connotations and may make patients less likely to seek treatment
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Discussion Tip: Have students discuss how these problems have changed over time and across diagnoses. Are there differences within this culture in terms of demographic factors (i.e., SES, ethnicity, geography, age)?
Summary of Clinical Assessment and Diagnosis
Clinical assessment and diagnosis
Aims to fully understand the client
Aids in understanding and ameliorating human suffering
Based on reliable, valid, and standardized information
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Conducting Research in Psychopathology
Questions driving a science of psychopathology
What problems cause distress or impair functioning?
Why do people behave in unusual ways?
How can we help people behave in more adaptive ways?
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Basic Components of Research, Part 1
Starts with a hypothesis or “educated guess”
Not all hypotheses are testable
Hypotheses in science are formulated so that they are testable
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Basic Components of Research, Part 2
Research design
A method to test hypotheses
Independent variable
The variable that causes or influences behavior
Dependent variable
The behavior influenced by the independent variable
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Independent variable – The variable that causes or influences behavior
Dependent variable – The change influenced by the independent variable
Considerations in Research Design
Internal validity vs. external validity
Internal validity: Extent to which results of a study are due to the independent variable
External validity: Extent to which results of a study are generalizable to the population it’s studying
Ways to increase internal validity by minimizing confounds
Use of control groups
Use of random assignment procedures
Use of analog models
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Control group: A comparison group of similar composition that is usually not manipulated in the same way as the group under study, or they are “healthy/normal”
EXAMPLES: In a study of anxiety treatment, compare anxious patients who are treated with anxious patients who do NOT receive treatment.
In a study of information processing, compare the performance of people who are depressed with the performance of people who are NOT depressed.
Analog model: Recreating the phenomenon under study in laboratory conditions
Statistical versus Clinical Significance, Part 1
Statistical methods—branch of mathematics
Helps to protect against biases in evaluating data
Statistical vs. clinical significance
Statistical significance—are results due to chance?
Clinical significance—are results clinically meaningful?
Statistical significance does not imply clinical meaningfulness
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Statistical significance = a result is unlikely to have occurred by chance.
Clinical significance = a result actually matters.
These are not always the same thing. When you have a really big sample size, you can achieve statistical significance if there is a small but consistent result across the whole group. But for any individual in that group, it might be a pretty meaningless result.
For example, take a group of 1000 insomniacs. If a new intervention helped all of them sleep an additional 10 minutes per night, that would probably be statistically significant. But for any one of them, the difference between 5 hours of sleep and 5 hours + 10 minutes of sleep will not make much of an impact on their functioning (i.e., not clinically significant).
Technology Tip: This site contains several links to pseudoscientific issues in psychology, and abnormal psychology in particular. http://www.psychology.org/links/Resources/Pseudoscience/
Statistical versus Clinical Significance, Part 2
Balancing statistical versus clinical significance
Evaluate effect size
Evaluate social validity
Patient uniformity myth
Researchers sometimes mistakenly see all participants as one homogenous group
Generalizability
The extent to which results are applicable to the larger population being studied
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Studying Individual Cases
Case study method
Extensive observation and detailed description of a client
Foundation of early historic developments in psychopathology
Limitations
Lacks scientific rigor and suitable controls
Internal validity is typically weak
Often entails numerous confounds
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Teaching Tip: Present a case study from the video library or your own clinical experience.
Research by Correlation, Part 1
Assess the degree to which levels of certain variables are linked to levels of other variables
Example: Higher levels of education are linked to higher levels of income
The nature of correlation
Statistical relation between two or more variables
No independent variable is manipulated
Range from –1.0 to 0 to +1.0
Negative vs. positive correlation
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Discussion Tip: Have students generate situations in which a correlational design is necessary and cannot be avoided due to natural or ethical constraints.
Research by Correlation, Part 2
Necessary in situations where you can’t manipulate variables
Limitations
Does not imply causation
Problem of directionality
Epidemiological research—an example of the correlational method
Incidence, prevalence, and course of disorders
Examples are AIDS, trauma following disaster
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Correlations
Figure 3.6
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FIGURE 3.6 These three graphs represent hypothetical correlations between age and sleep problems.
Research by Experiment, Part 1
Nature of experimental research
Manipulation of independent variables
Attempt to establish causal relations
Group experimental designs
Control groups
Placebo: Some participants are given an inactive treatment (e.g., sugar pill), but participants don’t know which treatment they are getting
Double-blind: Participants and assessors are unaware of what kind of treatment participants are getting
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Research by Experiment, Part 2
Comparative treatment designs
Type of group design
Compare different forms of treatment in similar persons
Addresses treatment process and outcome
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Single-Case Experimental Designs, Part 1
Nature of single subject design
Rigorous study of single cases
Varied experimental conditions and time
Repeated measurement
Evaluation of variability, level, and trend
Premium on internal validity
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Single-Case Experimental Designs, Part 2
Types of single-subject design
Withdrawal designs
Stop treatment to see if behavior/symptoms return to the way they were before treatment
Multiple baseline designs
Start treatment at different times in different conditions (e.g., in home vs. school settings)—see if changes occur in conjunction with introduction of treatment
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Single-Case Experimental Design
Figure 3.7
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Example of what we can learn from single-case experimental research
FIGURE 3.7 The top graph seems to show Wendy’s anxiety dropping significantly after treatment (measuring level). However, when you look at repeated measures before and after treatment, the middle graph reveals little change because her anxiety fluctuated a great deal (measuring variability). A different scenario is illustrated in the bottom graph (measuring trend), where her anxiety also varied. In general, there was a downward movement (improved anxiety) even before treatment, suggesting that she might have improved without help. Examining variability and trend can provide more information about the true nature of the change.
Multiple Baseline Design
Figure 3.8
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FIGURE 3.8 This figure shows how a multiple baseline design was used to illustrate that the treatment—functional communication training—was responsible for improvements in the children’s behaviors. The circles represent how often each child exhibited behavior problems (called challenging behavior), and the blue-shaded areas show how often they communicated without help from the teacher (referred to as unprompted communication). (From Durand, V. M., 1999. Functional communication training using assistive devices: recruiting natural communities of reinforcement, Journal of Applied Behavior Analysis, 32(3), 247–267. Reprinted by permission of the Society for the Experimental Analysis of Human Behavior.)
Genetic Research Strategies, Part 1
Behavioral genetics
Interaction between genes, experience, and behavior
Phenotype vs. genotype
Genotype: Genetic makeup
Phenotype: Observable characteristics (e.g., eye color, degree of shyness)
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Genetic Research Strategies, Part 2
Strategies used in genetic research
Family studies—behaviors/emotional traits in family members
Adoptee studies—separate environmental from genetic factors
Twin studies—psychopathology in fraternal vs. identical twins
Genetic linkage and association studies—sites of defective genes
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Technology Tip: The Online Mendelian Inheritance in Man database is a catalog of human genes and genetic disorders authored and edited by Dr. Victor A. McKusick and colleagues at Hopkins (http://www.ncbi.nlm.nih.gov/sites/entrez?db=OMIM).
Studying Behavior over Time, Part 1
Rationale and overview
How does the problem or behavior change over time?
Important in prevention and treatment research
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Studying Behavior over Time, Part 2
Time-based research strategies
Cross-sectional designs and the cohort effect
Longitudinal designs and the cross-generational effect
Sequential designs—combine both strategies
Assets and liabilities of time-based research strategies
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Cohort effect: Systematic differences in participants may simply be due to their age group. E.g. kids growing up during the AIDS crisis probably have unique opinions about STIs. (This isn’t because they’re in their 30s and 40s but rather because they heard about serious STIs as children)
Cross-generational effect - trying to generalize findings to groups whose experiences are very different from those of the study participants.
Research Design
Figure 3.9
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FIGURE 3.9 Two research designs, longitudinal & cross-sectional: Same people followed across time; people of different ages viewed at the same time.
Studying Behavior across Cultures
Value of cross-cultural research
Overcoming ethnocentric research
Assets and liabilities of cross-cultural research
Assets
To clarify how psychopathology manifests in different ethnic groups
Problems with cross-cultural research
Limited by available measures
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Programs of Research
Components of a research program
Set of interrelated research questions
Draw on several methodologies in finding answers
Conducted in stages, often involving replication
Allows for more nuanced, complete picture of a phenomenon
Replication is critical
Protects against fluke results
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Research Ethics, Part 1
Institutional review boards (IRBs) & the APA ethics code
Oversee the rights of human subjects participating in research
Make sure research and data are handled responsibly
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Technology Tip: This is the online version of the American Psychological Association’s Ethical Principles of Psychologists and Code of Conduct. http://www.apa.org/ethics/code.html
Research Ethics, Part 2
Ethical principals
Informed consent—historical evolution post-WWII
Competence—ability to provide consent
Voluntarism—lack of coercion
Full information—necessary information to make an informed decision
Comprehension—understanding about benefits and risks of participation
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Summary of Research Methods, Part 1
Nature of research
Establishing and testing hypotheses
Research design
Varies depending on the questions posed
Each has unique benefits and drawbacks
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Summary of Research Methods, Part 2
Abnormal psychology is founded in the scientific method
Understand the nature of abnormality and human suffering
Understand the causes of psychological disorders
Understand the course of psychological disorders
Understand how to prevent and treat psychological disorders
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Summary of Research Methods, Part 3
Replication is the cornerstone of science and programmatic research
Research must occur in the context of ethical considerations and values
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