40 statistics questions

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Exercise 22: Understanding Wilcoxon Signed-Rank Test

Questions to Be Graded

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Date: 26-07-2020

1: What are the mean and standard deviation (SD) for central-to-peripheral fat ratio at baseline for the depot-medroxyprogesterone acetate (DMPA) user group in the Dal’Ava et al. (2014) study? What are the mean and standard deviation (SD) for central-to-peripheral fat ratio at baseline for the TCu 380A intrauterine device (IUD) user group?

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2: What criteria were used to match the pairs of subjects from the DMPA and TCu 380A IUD groups? What were the study exclusion criteria? What is the purpose of the study exclusion criteria?

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3: According to the study narrative, at baseline there were no statistical differences between the DMPA and TCu 380A IUD groups for what nine variables? What do the results indicate?

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4: Dal’Ava et al. (2014) took steps such as matching criteria and assessing relevant variables at baseline to help ensure the matched pairs from the two groups (DMPA and TCu 380A IUD) were equivalent. In your opinion, do you believe these steps were sufficient to create equivalent matched pairs and groups? Provide a rationale for your answer.

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5: What was the p value for the Wilcoxon signed-rank test for variation in lean mass (kg) between the DMPA and TCu 380A IUD groups? Is this p value statistically significant? Provide a rationale for your answer.

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6: State the null hypothesis for variation in central-to-peripheral fat ratio (kg) from baseline to 12 months for the TCu 380A IUD group. Should the null hypothesis be accepted or rejected? Provide a rationale for your answer.

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7: What Wilcoxon signed-rank test result in Table 2 is p = 0.001? Is this p value statistically significant? Is the result clinically important? Provide rationales for your answers.

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8: What was the p value for the Wilcoxon signed-rank test for variation in fat mass from baseline to 12 months for the TCu 380A IUD group? Is this p value statistically significant? Provide a rationale for your answer.

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9: Dal’Ava et al. (2014) report a statistically significant (p = 0.02) weight change of 1.9 kg from baseline to 12 months for the DMPA group. In your own opinion, is this result clinically important? Provide a rationale for your answer.

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10: Are the Dal’Ava et al. (2014) findings ready for use in practice? Provide a rationale for your answer.

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  1. s_name: Amanda
  2. sclass: Statistics