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Chapter 11 chronic diseases

Questions and Answers: A Guide to Fitness and Wellness 3rd Edition

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COMING UP IN THIS CHAPTER

Identify the major types of cardiovascular disease, cancer, and diabetes

Assess your personal risk factors for these chronic diseases

Understand screening, diagnosis, and treatment options

Plan steps to reduce your risk for these diseases

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Table 11-1 Estimated Prevalence and Annual Mortality from Cardiovascular Disease, Cancer, and Diabetes

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Cardiovascular Disease

Cardiovascular disease (CVD) is a broad collection of many diseases that affect the heart (cardio) or blood vessels (vascular), or both

Deaths due to CVD have declined in the last 20 years

Still responsible for one in every three U.S. deaths

By 2030, over 40 percent of the U.S. population is projected to have some form of CVD

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What is cardiovascular disease? How many people die from it?

Q

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Types of Cardiovascular Disease

CVD is group of diseases that affects the heart and/or blood vessels

Heart attacks, strokes, coronary artery disease, hypertension, heart failure, and peripheral artery disease

Strokes are one of the most common forms of CVD

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Heart attacks and strokes affect different parts of the body, so why are they always lumped together?

Q

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Figure 11-1 Percentage breakdown of U.S. deaths from cardiovascular disease

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Types of Cardiovascular Disease

Coronary artery disease (CAD)

Usually caused by atherosclerosis

Buildup of plaque creating an occlusion

Can lead to arteriosclerosis

When atherosclerosis occurs in coronary arteries, CAD results

In artery leading to brain—stroke

In artery to a limb—peripheral artery disease

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What type of cardiovascular disease kills the most people?

Q

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Types of Cardiovascular Disease

CAD often has no symptoms as it develops

Once developed, it may reveal itself as:

Angina pectoris: chest pain as result of reduced blood supply to heart

Heart attack, or myocardial infraction (MI)

Blood supply in a coronary artery is blocked, depriving the heart of oxygen

Arrhythmia: a change in the normal pattern of the heartbeat

Cardiac arrest: sudden loss of responsiveness, pulse, and blood pressure

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Figure 11-2 Atherosclerosis and heart attack

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Types of Cardiovascular Disease

Stroke: when the blood (and oxygen) supply to a part of the brain is suddenly interrupted

Two major types:

Ischemic stroke: caused by a blocked artery

Hemorrhagic stroke: caused by a burst blood vessel

Transient ischemic attacks (TIAs)

“Mini-strokes”; caused by temporary blockage and typically do not cause lasting damage

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Is stroke caused by a blocked artery or burst artery?

Q

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Figure 11-3 Stroke

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Thrombus- a clot that forms in and occludes an artery to the brain

Embolus- a clot that forms elsewhere and travels to a cerebral artery

Cerebral hemorrhage- a blood vessel in the brain that bursts

Aneurysm- a weak spot in the blood vessel that forms a pouch that is subject to rupturing

Types of Cardiovascular Disease

Peripheral artery disease (PAD) occurs in the limbs, most commonly the legs

It may cause leg pain when walking, leg numbness or weakness, and coldness or paleness of the limb

Unless treated, it may lead to infections and amputation of the affected limb

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Can I really get CVD in my arms and legs?

Q

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Types of Cardiovascular Disease

Temporary increases in blood pressure are OK

Sustained high blood pressure (hypertension) is not OK

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If my blood pressure goes up naturally when I exercise, why is high blood pressure so bad?

More…

Q

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Types of Cardiovascular Disease

Blood pressure is the force of blood pumping against blood vessel walls

Systolic blood pressure (top number)

Force produced when the heart contracts

Diastolic blood pressure (bottom number)

Force between beats when the heart is at rest

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Types of Cardiovascular Disease

The recommended blood pressure is less than 120/80

Hypotension: low blood pressure

Less common

Systolic pressure below 90 or diastolic pressure below 60, or both

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For blood pressure, how high is too high?

Q

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Table 11-2 Blood Pressure Classification for Adults Age 18 and Older

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Types of Cardiovascular Disease

Heart attack can lead to heart failure

The heart is unable to pump a sufficient volume of blood

Often causes shortness of breath, fatigue, and fluid buildup

May compromise the ability of the kidneys to eliminate fluid

Heart failure complicated by fluid buildup is referred to as congestive heart failure

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Is heart failure the same as a heart attack?

Q

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Types of Cardiovascular Disease

Heart murmur refers to a variety of conditions

Most have no ill effects, and no treatment is needed

Result of inherited defects, infections, heart disease

May be related to heart valve function

Mitral valve prolapse (MVP)

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What can be done to eliminate a heart murmur?

Q

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Types of Cardiovascular Disease

Varicose veins are a product of improper valve function

Blood accumulation, twisting, and enlargement of affected veins

Caused by aging, hereditary, hormone changes

The best prevention is exercise and avoidance of excess weight

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19

What causes varicose veins, and how can I avoid them?

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Assessing Your Risk for Cardiovascular Disease: Factors You Cannot Control

You can’t reverse your familial predisposition to CVD, and some risks factors are not modifiable

Important to know family health history/ genetic predispositions

CVD that may be caused by inherited traits include certain forms of cardiomyopathy; arrhythmia; aneurysm; and Marfan’s syndrome

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Is there any way you can reverse genetically predisposed heart problems?

Q

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Assessing Your Risk for Cardiovascular Disease: Factors You Cannot Control

The prevalence of CVD rises with age

This is due to the wear and tear on the heart and blood vessels

Leads to structural and functional alternations, i.e. hypertension

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21

Why does getting older make a person more likely to have CVD?

Q

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Figure 11-4 Prevalence of high blood pressure among adults age 20 and over by age and sex

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Assessing Your Risk for Cardiovascular Disease: Factors You Cannot Control

Men are more likely to develop and die from CVD at a younger age

There is no clear reason for the difference

Women are more likely to die from a heart attack

On the horizon: studies that examine heart physiology and rhythms, and hormone fluctuations

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23

Why do more men have heart attacks than women?

Q

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Figure 11-5 Incidence of cardiovascular disease among adults age 20 and over, by age and sex

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Assessing Your Risk for Cardiovascular Disease: Factors You Cannot Control

Studies have found different rates of CVD and associated risk factors among different ethnic groups

The reasons are complex but include socioeconomic and biological factors

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How does ethnicity affect cardiovascular disease? What group or groups are most at risk?

More…

Q

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Assessing Your Risk for Cardiovascular Disease: Factors You Cannot Control

African Americans

Higher prevalence of CVD, hypertension, and stroke

Asian Americans and Latinos

Lower prevalence of heart disease than other groups

American Indians and Alaska Natives

Highest prevalence of stroke as a group

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Cardiovascular Disease Prevention

Some CVD risk factors are modifiable

Avoid tobacco

Keep alcohol use moderate and avoid drugs

Manage stress in healthy ways

Have regular screenings

Reduce elevated blood pressure

Maintain healthy cholesterol and triglyceride levels

Control diabetes

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Cardiovascular Disease Prevention

Body weight and food choices are only part of what affects CVD risk

Genes, age, biological sex, and ethnicity also count

Physical activity is an important factor in reducing one’s risk

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Are people who can eat all they want and not gain weight still at risk for cardiovascular disease?

Q

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Cardiovascular Disease Prevention

Many factors must be looked at to assess CVD risk

Among the factors: age, sex, smoking and drinking habits, eating patterns

You are a sum of your risk factors

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29

If you have excellent cardiovascular fitness but CVD runs in your family, do you have a greater risk than someone with no family history of CVD?

Q

Cardiovascular Disease Prevention

The best food plan for CVD prevention is balanced and moderate

Fiber-rich foods, low-fat dairy products, and seafood

Limit excess calorie intake from added sugars, fats, and processed foods

Keep alcohol intake moderate

Limit salt intake

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What types of food should I avoid and eat to help prevent cardiovascular disease?

Q

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Cardiovascular Disease Prevention

Added weight puts stress on the heart

People with excessive body fat are more likely to develop CVD even with no other risk factors

Increased physical activity and a balanced diet are key

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If I’m overweight is my risk a lot higher?

Q

Cardiovascular Disease Prevention

Avoid tobacco

Smoking not only raises cancer risk but also significantly increases risk for cardiovascular disease

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Smoking causes cancer, not cardiovascular disease—right?

More…

Q

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Two issues must be addressed in order to quit smoking, the nicotine addiction and psychological dependence.

One-third of all cigarette smokers try to quit each year, but less than 10% succeed.

Cigarette smoking is responsible for one out of ever five deaths in the U.S. annually.

Cardiovascular Disease Prevention

Smoking:

Affects fatty buildup (HDL and LDL levels)

Increases heart rate

Contributes to arrhythmias

Elevates blood pressure, reduces the oxygen level in the blood, and may trigger blood clots

The body slowly begins to heal as soon as someone quits

The risk of CVD falls by 50 percent just 1 year after quitting

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Two issues must be addressed in order to quit smoking, the nicotine addiction and psychological dependence.

One-third of all cigarette smokers try to quit each year, but less than 10% succeed.

Cigarette smoking is responsible for one out of ever five deaths in the U.S. annually.

Cardiovascular Disease Prevention

Keep alcohol use moderate, and avoid drugs

No more than 2 drinks per day for men or 1 drink per day for women

The effects of alcohol use can be positive or negative

Alcohol use is associated with a small increase in HDL and reduced clot formation

Excessive drinking can lead to high blood pressure, arrhythmia, stroke, sudden cardiac death, and obesity

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Does alcohol affect cardiovascular disease? What about other drugs?

Q

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Two issues must be addressed in order to quit smoking, the nicotine addiction and psychological dependence.

One-third of all cigarette smokers try to quit each year, but less than 10% succeed.

Cigarette smoking is responsible for one out of ever five deaths in the U.S. annually.

Table 11-3 Drugs and Related Cardiovascular Disease Complications

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Two issues must be addressed in order to quit smoking, the nicotine addiction and psychological dependence.

One-third of all cigarette smokers try to quit each year, but less than 10% succeed.

Cigarette smoking is responsible for one out of ever five deaths in the U.S. annually.

Cardiovascular Disease Prevention

Manage stress in healthy ways

There is a likely connection between stress and cardiovascular disease

The acute stress response is associated with elevated blood pressure and heart rhythms

Over time, the hormones associated with uncontrolled stress may alter glucose and blood fat levels

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Is stress a major factor in cardiovascular disease?

Q

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Cardiovascular Disease Prevention

Have regular screenings for:

Blood pressure

Cholesterol and triglycerides

Triglycerides

Diabetes

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How often do I have to get my blood pressure and cholesterol checked?

Q

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Cardiovascular Disease Prevention

Reduce elevated blood pressure

Hypertension is a type of cardiovascular disease that is a risk factor for other types of CVD

Keeping your blood pressure in check can help prevent CVD and complications from many conditions

Eat a balanced, low-sodium diet, engage in physical activity, maintain healthy weight, limit alcohol, and avoid smoking

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What can I do to lower my blood pressure?

Q

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Cardiovascular Disease Prevention

The connection between the foods you eat and the fats (lipids) in your blood are complex

Cholesterol is a waxy substance that occurs naturally in all cells of the body

Low-density lipoprotein (LDL)—bad cholesterol

High-density lipoprotein (HDL)—good cholesterol

Triglycerides

High levels are closely associated with CVD

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How does the fat in the foods I eat affect my cholesterol?

Q

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Table 11-4 Cholesterol and Triglyceride Classification

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Cardiovascular Disease Prevention

People with diabetes are two to four times more likely to develop cardiovascular disease

Elevated blood glucose levels can harm cardiovascular system

Metabolic syndrome: the cluster of conditions that puts people at risk for both heart disease and type 2 diabetes

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Why does diabetes affect the heart?

Q

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Table 11-5 Metabolic Syndrome

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Symptoms, Diagnosis, and Treatment of Cardiovascular Disease

Some forms of CVD have no visible symptoms

Testing is required

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Would I know if I had CVD?

Q

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Symptoms, Diagnosis, and Treatment of Cardiovascular Disease

Symptoms vary depending on the type of CVD

Signs to watch out for:

Chest pain

Fatigue

Shortness of breath

Leg pain

Palpitations

Light-headedness and fainting

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Does cardiovascular disease hurt? Would it affect my everyday activities?

Q

Symptoms, Diagnosis, and Treatment of Cardiovascular Disease

Look for signs

Chest and upper body discomfort (including jaw, neck, arms, back, stomach)

Shortness of breath

Cold sweat, nausea, light-headedness

Prompt treatment is crucial

Call 911

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45

How can you tell if a person is having a heart attack or a stroke?

Q

Table 11-6 Warning Signs of Heart Attack and Stroke

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Symptoms, Diagnosis, and Treatment of Cardiovascular Disease

Cardiopulmonary resuscitation (CPR)

Artificial blood circulation and respiration

For victims of cardiac arrest

Doesn’t usually restart the heart but can temporarily maintain circulation

Resuscitation usually requires defibrillation

AEDs

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When are you supposed to use CPR?

Q

Table 11-7 Tests for Diagnosing and Monitoring Cardiovascular Disease

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Symptoms, Diagnosis, and Treatment of Cardiovascular Disease

Lifestyle changes are the first line of defense

Other treatments include:

Medications

Coronary angioplasty and the placement of a stent

Coronary bypass surgery

Pacemakers

Heart valve repair or replacement

Heart transplant

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What kinds of medicine and help are available?

Q

Symptoms, Diagnosis, and Treatment of Cardiovascular Disease

Many forms of CVD are treatable

It is necessary to learn to manage CVD

Prevention is best

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How likely is it that someone will survive and recover from CVD? Is there a cure for it?

Q

Cancer

Cancer is a broad category of disease, characterized by the uncontrolled growth of cells

Tumors are abnormal clumps of cells

Benign means noncancerous

Polyps

Malignant tumors are known as cancer

Metastasize: spread

Primary tumor and secondary tumors

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What is cancer? What is the difference between malignant and benign tumors?

Q

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Figure 11-6 Normal cell division versus cancer cell division

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Cancer

About 13.7 million Americans with a history of cancer are alive today

Each year:

1.66 million new diagnoses

586,000 deaths

The number of new cases occurring each year has begun to decline slightly

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How many Americans have cancer?

Q

Types of Cancer

There are hundreds of types of cancer, most falling into one of these general groupings:

Carcinoma: in the skin or tissue lining or covering

80–90% of all cases

Sarcoma: in connective or supportive tissue

Lymphoma and myeloma: in the immune system

Leukemia: in blood-forming tissues

Central nervous system cancers: in the tissues of the brain or spinal cord

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Types of Cancer

The most frequently diagnosed cancers in the U.S. are basal cell carcinoma and squamous cell carcinoma

Noninvasive and highly curable

Lung cancer is the leading cause of cancer death

Lung, liver, and pancreatic cancers have poor survival rate

Diagnosis typically doesn’t happen until advanced

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55

What is the most common type of cancer? Which type is most severe?

Q

Table 11-8 Most Frequently Diagnosed Cancers in the U. S., 2012 estimates

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Assessing Your Risk for Cancer

Cancer risk is viewed in two ways:

Lifetime risk: probability of dying from cancer in your lifetime

Relative risk: extent of the relationship between a risk factor and a specific kind of cancer

Specific risk factors: heredity/genetics; age; gender; ethnicity; exposure to cancer-causing agents

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What are my chances of getting cancer?

Q

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Assessing Your Risk for Cancer

Heredity/genetics:

All cancers involve genetic mutation (damage)

Most are random

Only 5–10% are linked to inherited mutations

In evaluating your own risk, consider:

How many family members have had a particular type of cancer

Whether any were diagnosed at a young age

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If someone in my family has cancer, am I likely to get it too?

Q

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Assessing Your Risk for Cancer

The likelihood of being diagnosed with cancer rises with age

Genetic mutations and environmental factors build up

Increased exposure/decreased ability to repair damaged cells

Testicular cancer is an exception

Although uncommon, it is more prevalent in men aged 15–34

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Is cancer common in young adults? What types of cancer should I worry about now, when I’m 20?

Q

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Assessing Your Risk for Cancer

Men are more likely to develop cancer

Half of all men will develop cancer at some point in their life; one-third of all women

Data are inconclusive as to why

Lifestyle factors

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Are men or women more likely to get cancer?

Q

Assessing Your Risk for Cancer

Cancer is more common in African Americans

Other ethnicities have lower overall cancer rates but higher rates of specific cancers

Many factors contribute

Low incomes; limited access to health care, insurance

Cultural dietary factors and preferences for early marriage and childbirth

Genetics

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What groups are most at risk for cancer?

Q

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Assessing Your Risk for Cancer

A carcinogen is any substance that causes cancer

Radiation: X-rays, radon, sunlight, and tanning beds

Certain hormones and viruses

Asbestos

Tobacco

Solvents

Pesticides

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What’s a carcinogen?

Q

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Cancer Prevention

Avoid tobacco

Pay attention to your diet, physical activity, and body weight

One-third of all cancer deaths are due to poor nutrition and physical activity and/or excess body weight

Drink alcohol in moderation

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Is there a way to keep from getting cancer?

More…

Q

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Cancer Prevention

Be aware of infectious agents

Prevent with vaccination, antibiotic treatments, and lifestyle choices

Avoid unnecessary radiation

X-rays, radioactive substances, sunlight

Be cautious with sunlight, and avoid tanning lamps and booths

UV rays can lead to melanoma

Minimize stress

Be careful about chemical exposure

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Symptoms, Diagnosis, and Treatment of Cancer

Early cancer screening is critical

Screening tests performed before any symptoms appear can help find cancer in its earliest and most treatable stage

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When am I supposed to get all those cancer tests—and does everyone really need them?

Q

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Table 11-9 Cancer Screening Guidelines for the Early Detection of Cancer in Average-Risk Asymptomatic People

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Symptoms, Diagnosis, and Treatment of Cancer

General symptoms to watch for: CAUTION

Changes in bowel or bladder habits

A sore that does not heal

Unusual bleeding or discharge

Thickening or lump in breast or elsewhere

Indigestion or difficulty swallowing

Obvious change in wart or mole

Nagging cough or hoarseness

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What are symptoms of cancer?

Q

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Figure 11-7 ABCDEs of melanoma

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Symptoms, Diagnosis, and Treatment of Cancer

There is no single test to diagnose cancer

Possible tests include:

Biopsy

Imaging procedures

Tumor marker or lab tests

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What tests will a doctor do to figure out if a symptom really means cancer?

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Symptoms, Diagnosis, and Treatment of Cancer

When someone is diagnosed with cancer, the type of cancer and stage of development will be identified

Stage: I–IV (stage I, early; stage IV, advanced cancer that has spread)

In situ—found only in the layer of cells where it began

Prognosis

Typically decreases as stage increases

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What does it mean when they say that someone has stage IV cancer?

Q

Figure 11-8 Stages and spread of cancer

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Symptoms, Diagnosis, and Treatment of Cancer

Chemotherapy: drugs to kill cancer cells or inhibit their growth

Radiation therapy: use of high-energy rays to kill or damage cancer cells in an attempt to keep them from growing and/or spreading

Local rather than a systemic treatment

Surgery: removal of malignant tissue

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Once someone has cancer, what’s the best way to treat it?

Q

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Diabetes

Diabetes mellitus is a metabolic disorder characterized by problems with the body’s production or use of insulin

Causes glucose to build up in the blood stream, resulting in high blood sugar, or hyperglycemia

Because cells can’t obtain sufficient glucose, body loses main source of energy

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What is diabetes?

Q

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Diabetes

Prolonged hyperglycemia can cause damage to nerves, blood vessels, and other organs

Untreated, it can lead to ketoacidosis

Long-term complications include higher rates of CVD and lower life expectancy

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What’s bad about high blood sugar?

Q

Figure 11-9 Possible complications of diabetes

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Diabetes

Hypoglycemia or low blood sugar occurs when glucose levels in the blood are low

Relatively rare

Danger is to the brain because without glucose, brain cells die

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Can blood sugar be too low?

Q

Diabetes

Diabetes is more common in older adults

The number of cases among children and teens is growing

An estimated 79 million American adults have prediabetes

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Who is most likely to develop diabetes?

Q

Types of Diabetes

There are three primary types of diabetes:

Type 1 diabetes: an autoimmune disease attacking and destroying the insulin-producing cells of the pancreas

Type 2 diabetes: the pancreas produces insulin, but cells don’t respond properly to the insulin

Insulin resistance

Gestational diabetes: high glucose levels during pregnancy

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Are some kinds of diabetes more dangerous than others?

Q

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Types of Diabetes

Before developing type 2 diabetes, people often develop prediabetes, impaired glucose tolerance

Higher than normal glucose, but not high enough to be classified as diabetes

Can suffer the same complications as those with diabetes

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Can you have high blood sugar without having diabetes?

Q

Figure 11-10 Normal glucose metabolism, type 1 diabetes, and type 2 diabetes

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Assessing Your Risk for Diabetes

Different types have different causes

Type I: autoimmune condition

Genetic and viral factors are suspected to be the primary trigger

The exact cause is unknown

Develops most often in children

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What causes diabetes?

More…

Q

Assessing Your Risk for Diabetes

Type II: causes unknown; risk factors include:

Age 45 or older

BMI over 25; not physically active

A family history of diabetes

High blood pressure or high cholesterol

Gestational diabetes

Blood glucose levels that are higher than normal

African American, American Indian, Asian American, Pacific Islander, or Hispanic/Latino genetic heritage

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More…

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Assessing Your Risk for Diabetes

Type II: causes unknown; risk factors include:

Polycystic ovary syndrome

Dark, thick, velvety skin around the neck or in the armpits

Blood vessel problems affecting the heart, brain, or legs

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Figure 11-11 Lifetime risk of diabetes by BMI at age 18

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Assessing Your Risk for Diabetes

A family history of diabetes is a risk factor in the disease

Positive lifestyle choices can delay or prevent the onset of diabetes

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If both my dad and my grandfather have diabetes, will I get it too?

Q

Assessing Your Risk for Diabetes

As a nation, we are getting fatter, and obesity is a key risk factor for type 2 diabetes

The risk is greater for those who are overweight at a young age

Lifestyle choices related to diet and exercise are key to prevention

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86

I keep hearing that more and more people are getting diabetes. Why is that?

Q

Diabetes Prevention

Eating anything in excess can cause obesity, a key risk factor

Sugar itself does not directly cause diabetes

Diabetes is related to genetics and lifestyle choices

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Does eating too much sugar cause diabetes?

Q

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Symptoms, Diagnosis, and Treatment of Diabetes

Symptoms to watch for:

Increased thirst

Increased hunger after eating

Dry mouth

Frequent urination

Unexplained weight loss or weight gain

Fatigue

Blurred or decreased vision

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How would I know if I had diabetes?

More…

Q

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Symptoms, Diagnosis, and Treatment of Diabetes

Symptoms to watch for:

Numbness or tingling in hands or feet

Slow-healing sores or cuts

Itching of the skin, most often around the vaginal or groin area

Frequent yeast infections

Impotency

Loss of consciousness (in rare cases)

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Symptoms, Diagnosis, and Treatment of Diabetes

Adults over age of 45 should be tested every 3 years

If at high risk, early and more frequent testing required

A1C test

Fasting plasma glucose test (FPG)

Oral glucose tolerance test (OGTT)

Urinalysis

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Do I need to be tested for diabetes even if I don’t have any symptoms?

Q

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Figure 11-2 Criteria for diagnosing diabetes

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Symptoms, Diagnosis, and Treatment of Diabetes

Type 1: requires daily doses of insulin

Self-injections

Pumps

Type 2: oral medication and lifestyle strategies

Gestational: lifestyle strategies and insulin in some cases

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I have a friend who has to give herself shots. Does everyone with diabetes have to do this?

Q

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Symptoms, Diagnosis, and Treatment of Diabetes

Self-management of diabetes is crucial

Learn how to self-test glucose levels

Understand signs of diabetes complications

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What about those ads for diabetes supplies? Besides taking medication, what does someone with diabetes have to do?

Q

Putting it All Together for Chronic Disease Prevention

Get regular physical activity

Eat a balanced diet

Don’t smoke, or stop if you do

Consume alcohol only in moderation

Give your health history to your health care provider

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Table 11-10 Top Lifestyle Choices for Preventing Chronic Disease

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