case 2

In this module, you will complete a  discussion case. You will identify problems, possible solutions, and consequences. This type of case study is designed for you to lead the analysis, and it will test your ability to apply key terms, concepts, and principles from the textbook and the lectures.

Objectives

1. Apply knowledge of basic neurophysiology principles to predict the potential effects of altering sodium and potassium ion channel function on neuronal excitability.

2. Predict the symptoms produced by alteration of neuron excitability in various regions or parts of the peripheral and central nervous systems.

3. Connect the role of ion channel function to a variety of diseases and pathological conditions.

Instructions

1. Download the Neurophysiology Case Study

 . There are 19 questions on this assignment.

 Type your answers into the PDF or download a Word version of the questions

   or print the assignment, write by hand, and scan back to PDF.

 Upload your completed PDF or completed Word worksheet.

PSB3002 – Nelson – Module 2 – Neurophysiology Case Study Worksheet – Escape from Planet Soma All questions must be answered to earn full credit. Partial work is graded with the posted rubric. Kindly consider using a different color for your answers to help with grading workflow. This case study has 19 required questions. Name: Space Alter Ego: Intrepid Card 1 1. How will the non-functional sodium channels affect the signaling capabilities of a neuron? 2. What type of information do nociceptive neurons carry? 3. Why would having this mutant gene be so terrible? Card 2 4. What effect will the destruction of myelin have on the signaling capability of a neuron? 5. Explain why this occurs. 6. What will happen to you if you are forced to drink the alien “orange juice”? Card 3 7. How will the signaling of a neuron be affected if the voltage-gated sodium channels open at a more negative membrane potential? 8. How will preventing the inactivation of sodium channels affect the signaling capability of a neuron? 9. What nasty effects will this toxin have on motor pathways? Card 4 10. What effect will the dendrotoxin have on the signaling capability of a neuron? 11. What will happen to you if your motor neurons are exposed to this toxin? Card 5 12. To what other type of potassium channel is Oligodendrog referring? 13. What effect will opening more of these channels have on the excitability of a neuron? 14. What will happen to you when sevofurane reaches the reticular formation neurons that control sleep and consciousness?

Card 6 15. How will increasing extracellular potassium affect the signaling capability of a neuron? 16. What type of cell normally regulates levels of extracellular potassium in the CNS? 17. What “terror” will this method produce if injected into your brain tissue? Card 7 18. How will the excitability of a neuron be affected by sodium channels that open at more positive membrane potentials? 19. How does this lead to seizure activity in the brain?