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Case Study 10 2020

A 59 year old man, presented to the emergency room complaining of fever and chills for 4 days, with dizziness over the last 24 hours.

Also complained of intermittent diarrhea and constipation over the last 6 months with occasional bloody stool.

Past history: Heavy smoker of 45 years and admitted drinking alcohol regularly.

Examination: Rapid breathing with lung sounds clear. Temperature 102.3 degrees F.

Hypotensive, tachycardic, and an appreciable heart mummer.

Blood was drawn for CBC and blood cultures. A stool specimen was collected for occult blood and a chest x-ray was performed.

Instructions:

Utilize the table below and description above to evaluate the status of your patient. When writing up your case study remember to enter the reference ranges and interpretations.

CBC Results

 

 

Admission

Reference ranges

Interpretation

WBC

9.1 X109 /L

3.6 – 10.6 x 109 /L

Normal

RBC

4 X10 12/L

4.00 – 6.00 x 1012/L

Normal

Hemoglobin

12.2 g/dL

12.0 – 18.0 g/dL

Normal

Hematocrit

40 %

35% – 50%

Normal

MCV

100 fL

76 – 100 fL

Normal

MCH

32 pg

26 – 34 pg

Normal

MCHC

30 g/dL

32 – 36 g/dL

Low

RDW-CV

15.6 %

11.5 – 14.5%

High

Platelets

458 X 109 /L

150 – 450 x 109 /L

High

MPV

7.2 fL

7 – 9 fL

Normal

Differential

 

Neutrophils

52%

50 – 70%

Bands

10%

Lymphocytes

35%

18 – 42%

Monocytes

1%

2 – 11%

Eosinophils

0

1 – 3%

Basophils

0

0 – 2%

Metamyelocytes

2

Morphology

 

 

1+ Macrocytes

 

2+ Microcytes

 

1+ Ovalocytes

 

1+ basophilic stippling

 

2+ hypochomia

 

1+ polychromatophilia

 

2+ toxic granulation

 

Rare Dohle bodies

 

Rare hypersegmentation

 

2 nucleated RBC's

Bacterial Culture

 Results

 

All blood cultures

 Positive within 24 hours

 

Gram Stain

 Gram positive cocci in chains

Culture on BAP

 gamma hemolytic, small grey colonies

Biochemical Results

 

 

Catalase

 Negative

Bile Esculin agar

 growth with black precipitate

6.5% NaCl

 Negative

L-pyrrolidinyl beta-naphthylamide PYR test

 Negative

Instructions:

Use the questions below to guide you in writing up your case study. Remember to refer to the case study description and rubric when planning and writing your case study.

1. What criteria may be used to determine if a positive blood culture is due to contamination or bacteremia?

2. Does the patient have a bacteremia or a septicemia?

3. Given the colonial morphology, biochemical reactions and gram stain what is the most likely organism?

4. What other methods may be employed to get a definitive identification of this organism.

5. Relating back to the patient, what of the numerous underlying medical problems is associated with this organism?

6. How do the CBC results relate to the patient’s condition?

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