Calculation quiz

1. Using the Cockcroft-Gault equation, calculate creatinine clearance for the following patient: 70 year old female, 5’6” tall, 150 lb, SCr = 1.2 mg/dL. Round your answer to the nearest 1 mL/min.

2. A 1-year-old male weighing 28 lbs is diagnosed with acute otitis media and will be treated with amoxicillin/clavulanate (Augmentin®). The recommended dosing is 90 mg/kg/day, divided every 12 hours. How many mL of 600 mg/5 mL would be given with each dose? Round your answer to the nearest 0.5 mL.

3. A 7-year-old female weighing 55 lbs presents with a severe asthma exacerbation and will be treated with prednisolone (Orapred®). Recommended dosing is 1 mg/kg/day in 2 divided doses. How many milligrams would be prescribed per dose? Round your answer to the nearest mg.

4. A 10-year-old female weighing 80 lbs presents with a urinary tract infection and will be treated with sulfamethoxazole/trimethoprim (Bactrim®). Dosing for this medication is typically based on the trimethoprim component. Suspension is available as 200 mg of sulfamethoxazole and 40 mg of trimethoprim in every 5 mL. Dosing for this indication is trimethoprim 8 mg/kg/day divided every 12 hours. How many milliliters of sulfamethoxazole would be given with each dose? Round your answer to the nearest 0.5 mL.

5. A 6-year-old male weighing 50 lbs presents complaining of a sore throat and has a positive rapid strep test. He will be treated with amoxicillin (Amoxil®) with dosing of 50 mg/kg/day. How many milligrams/day would be prescribed? Round your answer to the nearest 5 mg.

6. From question #5 - how many mL would this be (using 400 mg/5 mL concentration)? Round your answer to the nearest 0.5 mL.

7. A 2 month old weighing 9 lbs presents with erosive esophagitis. This will be treated with ranitidine (Zantac®) 10 mg/kg/day in 2 divided doses. Ranitidine comes as a 15 mg/mL concentration. How many milliliters would be recommended for each dose? Round your answer to the nearest 0.1 mL.

8. From question #7 – how many mL would be needed for a 30 day supply? Round your answer to the nearest 5 mL but be sure to give adequate supply.

9. A mother of a 4 year old weighing 30 lbs calls your office asking for dosing recommendations for ibuprofen (Motrin®) for a fever. Recommended dosing is 5-10 mg/kg every 6-8 hours as needed. Ibuprofen suspension concentration is 100 mg/5 mL. What range, in milliliters, would be appropriate for this patient for each dose? Round your answer to the nearest 0.5 mL.

10. From question #9 – the mother decides that she would rather use acetaminophen (Tylenol®). Dosing recommendation is 10-15 mg/kg/dose and the suspension concentration is 160 mg/5 mL. What range, in milliliters, would be appropriate for this patient for each dose? Round your answer to the nearest 0.1 mL.