assig PathoM1W2

AssigmentM1W2Patho.docx

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Case scenario:

A 49-year-old patient with rheumatoid arthritis comes into the clinic with a chief complaint of a fever. Patient’s current medications include atorvastatin 40 mg at night, methotrexate 10 mg po every Friday morning and prednisone 5 mg po qam. He states that he has had a fever up to 101 degrees F for about a week and admits to chills and sweats. He says he has had more fatigue than usual and reports some chest pain associated with coughing. He admits to having occasional episodes of hemoptysis. He works as a grain inspector at a large farm cooperative. After extensive work-up, the patient was diagnosed with Invasive aspergillosis.

At least 2-page case study analysis in which you: (does not count page: title, introduction, conclusion, and references pages)

· Explain why you think the patient presented the symptoms described.

· Identify the genes that may be associated with the development of the disease.

· Explain the process of immunosuppression and the effect it has on body systems.

Develop the work, putting each question with its answer individually, Not explain altogether.

using formal APA writing convention, using the 7th Edition

References at least 4 and not more than 5 years ago

Plagiarism document…. Thank you

please read the teacher's instructions, to correctly develop the work

In your paper:

1. Please use references that have been published in the past 5 years. Please use primary research and references rather than patient webpages. Mayo Clinic is not a scholarly resource.

2. Please make sure to include an in-text citation for all non-original assertions. A non-original assertion is any information you obtained from a source. For example, you learned about cytokines and infection from a source; you need to cite that source. At a minimum, cite the initial sentence and the last sentence of the paragraph if it relates to the disease that you are discussing. You do not have to cite the actual case study that was posted.

3. If you struggle with APA, please review the specific content in your APA book. Please also use the APA resources and Writing Center that are available to you.

4. Please avoid the use of the first person in your case studies.

5. Please remember to include an introduction and conclusion in your papers. Please also be sure to include a purpose statement for the paper (i.e. "The purpose of this paper is to..."). You all come from different backgrounds including educational backgrounds and writing experience, and elements like these can sometimes be forgotten when we have page limits, etc with our school papers.

6. Please upload Word documents, not PDFs.

7. Please do not include the assignment instructions in your paper. You can use headings per APA, but headings should not be the assignment instructions. Please review use of headings in your APA book.

8. Please make sure to submit your assignments/papers by the due date/time. Please review the information on late assignments in the syllabus. Please email me if you have an emergency that would preclude you from completing your assignment before the due date. If you do submit your paper late, the paper will receive limited feedback.

9. Please review the rubric- the rubric is used to review the patho content of your paper. I will also evaluate your use of APA.

Teacher’s note: the following are examples (not all inclusive) of resources/websites deemed inadmissible for scholarly reference:

1. Up to Date (must use original articles from Up to Date as a resource)

2. Wikipedia

3. Cdc.gov- non healthcare professionals section

4. Webmd.com

5. Mayoclinic.com

McCance, K. L. & Huether, S. E. (2019). Pathophysiology: The biologic basis for disease in adults and children (8th ed.). St. Louis, MO: Mosby/Elsevier.

· Chapter 1: Cellular Biology; Summary Review

· Chapter 2: Altered Cellular and Tissue Biology: Environmental Agents(pp. 46-61; begin again with Manifestations of Cellular Injury pp. 83-97); Summary Review

· Chapter 3: The Cellular Environment: Fluids and Electrolytes, Acids, and Bases,

· Chapter 4: Genes and Genetic Diseases (stop at Elements of formal genetics); Summary Review

· Chapter 5: Genes, Environment-Lifestyle, and Common Diseases (stop at Genetics of common diseases); Summary Review

· Chapter 7: Innate Immunity: Inflammation and Wound Healing

· Chapter 8: Adaptive Immunity (stop at Generation of clonal diversity); Summary Review

· Chapter 9: Alterations in Immunity and Inflammation (stop at Deficiencies in immunity); Summary Review

· Chapter 10: Infection (stop at Infectious parasites and protozoans); (start at HIV); Summary Review

· Chapter 11: Stress and Disease (stop at Stress, illness & coping); Summary Review

· Chapter 12: Cancer Biology (stop at Resistance to destruction); Summary Review

· Chapter 13: Cancer Epidemiology (stop at Environmental-Lifestyle factors); Summary Review

Justiz-Vaillant, A. A., & Zito, P. M. (2019). Immediate hypersensitivity reactions. In StatPearls. Treasure Island, FL: StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/

Credit Line: Immediate Hypersensitivity Reactions - StatPearls - NCBI Bookshelf. (2019, June 18). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK513315/. Used with permission of Stat Pearls. Note: This article was presented in the Week 1 resources. If you read it previously you are encouraged to review it this week.

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Develop a 2-page case study analysis, examining the patient symptoms presented in the case study. Be sure to address the following: Explain why you think the patient presented the symptoms described.

28 (28%) - 30 (30%)

The response accurately and thoroughly describes the patient symptoms. The response includes accurate, clear, and detailed reasons, with explanation for the symptoms supported by evidence and/or research, as appropriate, to support the explanation.

25 (25%) - 27 (27%)

The response describes the patient symptoms. The response includes accurate reasons, with explanation for the symptoms supported by evidence and/or research, as appropriate, to support the explanation.

23 (23%) - 24 (24%)

The response describes the patient symptoms in a manner that is vague or inaccurate. The response includes reasons for the symptoms, with explanations that are vague or based on inappropriate evidence/research.

0 (0%) - 22 (22%)

The response describes the patient symptoms in a manner that is vague and inaccurate, or the description is missing. The response does not include reasons for the symptoms, or the explanations are vague or based on inappropriate or no evidence/research.

Identify the genes that may be associated with the development of the disease.

23 (23%) - 25 (25%)

The response includes an accurate, complete, detailed, and specific analysis of the genes that may be associated with the development of the disease.

20 (20%) - 22 (22%)

The response includes an accurate analysis of the genes that may be associated with the development of the disease.

18 (18%) - 19 (19%)

The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease.

0 (0%) - 17 (17%)

The response includes a vague or inaccurate analysis of the genes that may be associated with the development of the disease is missing.

Explain the process of immunosuppression and the effect it has on body systems.

28 (28%) - 30 (30%)

The response includes an accurate, complete, detailed, and specific explanation of the process of immunosuppression and the effect it has on body systems.

25 (25%) - 27 (27%)

The response includes an accurate explanation of the process of immunosuppression and the effect it has on body systems.

23 (23%) - 24 (24%)

The response includes a vague or inaccurate explanation of the process of immunosuppression and the effect it has on body systems.

0 (0%) - 17 (17%)

The response includes a vague or inaccurate explanation of the process of immunosuppression and the effect it has on body systems.

Written Expression and Formatting - Paragraph Development and Organization: Paragraphs make clear points that support well-developed ideas, flow logically, and demonstrate continuity of ideas. Sentences are carefully focused—neither long and rambling nor short and lacking substance. A clear and comprehensive purpose statement and introduction are provided that delineate all required criteria.

5 (5%) - 5 (5%)

Paragraphs and sentences follow writing standards for flow, continuity, and clarity. A clear and comprehensive purpose statement, introduction, and conclusion are provided that delineate all required criteria.

4 (4%) - 4 (4%)

Paragraphs and sentences follow writing standards for flow, continuity, and clarity 80% of the time. Purpose, introduction, and conclusion of the assignment are stated, yet are brief and not descriptive.

3 (3%) - 3 (3%)

Paragraphs and sentences follow writing standards for flow, continuity, and clarity 60%–79% of the time. Purpose, introduction, and conclusion of the assignment are vague or off topic.

0 (0%) - 2 (2%)

Paragraphs and sentences follow writing standards for flow, continuity, and clarity < 60% of the time. No purpose statement, introduction, or conclusion were provided.

Written Expression and Formatting - English Writing Standards: Correct grammar, mechanics, and proper punctuation

5 (5%) - 5 (5%)

Uses correct grammar, spelling, and punctuation with no errors.

4 (4%) - 4 (4%)

Contains a few (1 or 2) grammar, spelling, and punctuation errors.

3 (3%) - 3 (3%)

Contains several (3 or 4) grammar, spelling, and punctuation errors.

0 (0%) - 2 (2%)

Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding.

Written Expression and Formatting - The paper follows correct APA format for title page, headings, font, spacing, margins, indentations, page numbers, running heads, parenthetical/in-text citations, and reference list.

5 (5%) - 5 (5%)

Uses correct APA format with no errors.

4 (4%) - 4 (4%)

Contains a few (1 or 2) APA format errors.

3 (3%) - 3 (3%)

Contains several (3 or 4) APA format errors.

0 (0%) - 2 (2%)

Contains many (≥ 5) APA format erro