Instructions: Unit V Research Report BIO 1030

Running head: LEUKEMIA 1

LEUKEMIA 2

CAUSES, FORMS, DIAGNOSIS, TREATMENT AND THE FUTURE OF LEUKEMIA

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Causes, Forms, Diagnosis, Treatment and the Future of Leukemia

LeBlanc TW; Fish LJ; Bloom CT; El-Jawahri A; Davis DM; Locke SC; Steinhauser KE; Pollak KI. (2017). Patient experiences of acute myeloid leukemia: A qualitative study about diagnosis, illness understanding, and treatment decision-making. Psycho-Oncology, Dec; Vol. 26 (12), pp. 2063 2068;

This article discusses the challenges that patients with leukemia face. It particularly discusses the acute myeloid leukemia (AML), which presents sudden changes in the health of patients thus making it difficult for them to adapt and cope. This is besides the complex information that is presented to them as well as the pressure that is put on them to make quick treatment decisions with very little options. There is an indication of the little information that individuals have regarding the experiences of people diagnosed with AML. The article is well written with a lot of research that clearly outlines the process that were used to get the results. Thus, this article will be a great resource as it reveals the experiences and difficulties that are faced by those who suffer from AML. In this case, it will be useful in the assisting to find the right approaches towards treatment and care given to these patients as well as the varied improvements that can be made in the areas to make sure that the patients are comfortable and are treated well.

Nabhan C; Mato AR. (2017). Economic Modeling of the Cost of Chronic Lymphocytic Leukemia Therapy: It Is About the Model. Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology, Jun 01; Vol. 35 (16), pp. 1863 1864.

A lot of research has been done regarding the causes, symptoms and the treatment of leukemia. However, in this article one of the most important and less discussed aspects of the disease is highlighted. The authors suggest the creation of a model that will help in the proper evaluation of the economic costs that are related to the therapy that is offered to patients with chronic lymphocytic leukemia. It attempts to find the best options that can be taken to reduce the associated costs in order to make the treatment options available and accessible to the patients. Through a proper analysis of the various models, it becomes possible to create a suitable model to ensure that the costs can be reduced as much as possible for the patients suffering from leukemia. This article is helpful as it highlights the costs that are related to the treatment of the chronic lymphocytic leukemia. It helps to understand some of the challenges that are presented to these patients when making decisions regarding their treatment and the need to come up with models that will make these treatment options affordable and accessible to the patients.

RADA, Olga-Alina; BREZOVAN, Diana; MĂRAN, Corina Luminița; OSTAN, Mihaela.(2017). Morphological and chemical changes in blood cells in acute leukaemia in humans note 2. Morphological changes of figurative elements blood and bone marrow in patients with acute leukaemia suspicion. Research Journal of Agricultural Science. Vol. 49 Issue 3, p69-73. 5p

Various strategies and methods are provided towards the ability to examine the bone marrow species for likely infection or infection with the tumor. It involves the capturing and ability to highlight the morphological changes that are associated with the examination of the peripheral blood smear or the bone marrow. These factors are important in the performance of the diagnosis for acute leukemia. This means that it is important to provide an examination on the blood samples in order to ascertain whether they are at risk of leukemia. Through the performance of the studies, the authors reveal that depending on the morphological structures of the blood smears, it is possible for the patient to suffer from either type I and II blasts. Thus it is an important article in the way that it provides the guidelines towards the diagnosis of leukemia with the ability to classify the condition as either acute lymphoblastic lymphoma or establishing the need to perform bone marrow aspirate for further investigation depends on the polymorphism of the sample structures.

Norwood, Marlena S.; Lupo, Philip J.; Chow, Eric J.; Scheurer, Michael E.; Plon, Sharon E.; Danysh, Heather E.; Spector, Logan G.; Carozza, Susan E.; Doody, David R.; Mueller, Beth A. (2017). Childhood cancer risk in those with chromosomal and non-chromosomal congenital anomalies in Washington State: 1984-2013. LoS ONE. Vol. 12 Issue 6, p1-15. 15p.

The various causes of cancer have been discussed and researched in a number of the related studies performed. With the ability to establish the different causes, it is possible to establish the appropriate mode of prevention for the condition. The authors perform an investigation to determine the genetic causes of childhood risks of cancers. Most of the time, these causes are linked to chromosomal anomalies. This increases the risks of childhood cancers and may also be the results of the large effects that it Down Syndrome has on leukemia. This is a study that aims at expanding the knowledge that people have on this issue. It is an appropriate article that provides insights regarding the associations between non chromosomal anomalies and the different types of leukemia. The study shows that the presence of congenital anomalies increases the chances of leukemia in children, As such, this information is important since it will help in the establishment of preventive measures to ensure that the possible causes of chromosomal leukemia are avoided. Although non chromosomal associations are also present, it will help in the reduction of chromosomal associations with leukemia.

References

LeBlanc, T. W., Fish, L., J., Bloom, C. T., El-Jawahri, A., Davis, D. M., Locke, S. C., Steinhauser, K. E., & Pollak, K. I. (2017). Patient experiences of acute myeloid leukemia: A qualitative study about diagnosis, illness understanding, and treatment decision-making. Psycho-Oncology, Dec; Vol. 26 (12), pp. 2063-2068.

Nabhan, C., & Mato, A. R. (2017). Economic Modeling of the Cost of Chronic Lymphocytic Leukemia Therapy: It Is About the Model. Journal Of Clinical Oncology: Official Journal Of The American Society Of Clinical Oncology, Jun 01; Vol. 35 (16), pp. 1863 1864.

Norwood, Marlena S., Lupo, Philip J., Chow, Eric J., Scheurer, Michael E., Plon, Sharon E., Danysh, Heather E., Spector, Logan G., Carozza, Susan E., Doody, David R., Mueller, Beth A. (2017). Childhood cancer risk in those with chromosomal and non-chromosomal congenital anomalies in Washington State: 1984-2013. LoS ONE. Vol. 12 Issue 6, p1-15. 15p.

RADA, Olga-Alina, BREZOVAN, Diana, MĂRAN, Corina Luminița, OSTAN, Mihaela.(2017). Morphological and chemical changes in blood cells in acute leukaemia in humans note 2. Morphological changes of figurative elements blood and bone marrow in patients with acute leukaemia suspicion. Research Journal of Agricultural Science. Vol. 49 Issue 3, p69-73. 5p