Assignment: Evidence-Based Project, Part 3: Advanced Levels of Clinical Inquiry and Systematic Reviews
Advanced Levels of Clinical Inquiry and Systematic Reviews Assignment: Part 3
INTRODUCTION
The clinical issue of interest in this study is the management of type 2 diabetes in patients living with this condition.
Type 2 diabetes mellitus is one of the growing pandemic that leads to morbidity and mortality.
Most of the research studies have found that normalizing glycemia helps in preventing diabetes mellitus-related complications.
Glycemic control can be achieved through patient-directed marketing, quality-of-care measures, quality improvement interventions and guidelines.
PICO(T) QUESTION
In patients with diabetes type 2, does the use of combined therapy result in better glycemic control when compared to the use of standard care alone in 8 months?
P- (Patient, population, or problem): All patients with diabetes type 2.
I- (Intervention): the use of combined therapy.
C- (Comparison): the use of combined therapy versus the use of standard care.
O- (Outcome): improved glycemic control.
T- (Time): 8 months.
Research Databases
Database search defines the essential aspects that are linked to the underlying issue and how the information is searched.
The crucial nursing journals are found in the databases located in the university library.
The leading searching terms used when searching for the four databases include: the use of combined therapy for glycemic control, and the use of standard care for glycemic control.
The four research databases utilized in this research include: PubMed, CHNAHL, Medline, and ScienceDirect.
Peer-reviewed Articles
The peer-reviewed articles used in this research study include those published in less than 5 years ago.
It is essential to improve on the accuracy of the findings because it emphasizes on the significant changes, which help in defining a strong focus on the research outcomes.
Thus, to improve the efficacy of the results, it is essential to focus on the latest publications because they provide current information on the research issue.
Articles
Cahn, A., & Cefalu, W. T. (2016). Clinical Considerations for Use of Initial Combination Therapy in Type 2 Diabetes. Diabetes Care, 39(Supplement 2), S137–S145. https://doi.org/10.2337/dcs15-3007
Cai, X., Gao, X., Yang, W., Han, X., & Ji, L. (2018). Efficacy and Safety of Initial Combination Therapy in Treatment-Naïve Type 2 Diabetes Patients: A Systematic Review and Meta-analysis. Diabetes Therapy, 9(5), 1995–2014. https://doi.org/10.1007/s13300-018-0493-2
Please add one more article using PubMed database.
Reach, G., Pechtner, V., Gentilella, R., Corcos, A., & Ceriello, A. (2017). Clinical inertia and its impact on treatment intensification in people with type 2 diabetes mellitus. Diabetes & Metabolism, 43(6), 501–511. https://doi.org/10.1016/j.diabet.2017.06.003
Levels of Evidence
The evidence of the Study by (Cahn & Cefalu, 2016) is level III because it provide evidence from the summaries developed from systematic reviews.
The evidence of the study by (Cai et al., 2018) is level I because the evidence is obtained from meta-analysis and systematic reviews.
The evidence of the study by (Lavernia et al., 2015) is level III because it provide evidence from the summaries developed from systematic reviews. Please do this for the new article.
The evidence of the study by (Reach et al., 2017) is level III because it provide evidence from the summaries developed from systematic reviews.
Strengths of using systematic reviews
A systematic review refer to the summary of medical literature in which researchers utilize explicit and reproducible approaches to search, appraise and synthesize all the available evidence on a specific issue.
Meta-analysis is a type of systematic review that utilizes various studies.
Systematic reviews are essential because:
Researchers use explicit methods to identify and select studies; thus, reducing biases and provide reliable and accurate conclusions.
Improve the consistency and generalizability of the results.
Summarizes findings from various studies hence reducing delay in time during the process of research discoveries to implementation.