A.docx

1/ Granulocyte transfusion (GTX)

Define this treatment and summarize when it is used clinically

2/ Granulocyte Colony Stimulating Factor (rhG-CSF)

What is the mechanism of action of this therapeutic? What is it used to treat? What are the risks involved in its long-term use?

3/ CXCR4 chemokine receptor and its ligand SDF-1

What is the role of CXCR4/SDF-1 interaction in the homing and release of immune cells from the bone marrow?