400-500 case
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8.1HIVAIDS101asprepforFireintheBloodfilm.pptx8.1: HIV 101
GEOG 3692: Introduction to Global Public Health
Caitlin M. Ryan, PhD
University of Colorado Boulder
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Exam study guide topics
Describe the difference between HIV and AIDS, and how HIV progresses
Know the 3 ways HIV is transmitted
Understand the main treatment options for HIV and the expected outcomes with and without treatment
Does the McKeown hypothesis hold true for HIV as it did for tuberculosis in the past? Why or why not?
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T / CD4 cells
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HIV vs AIDS?
HIV: Human Immunodeficiency Virus detected in blood
AIDS:
having 200 or less CD4 cells/liter
OR having an opportunistic infection and being HIV positive.
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CD4 (T4) cells and Opportunistic Infections
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Latent Infection
Initially people are asymptomatic
Lasts 8 years on average (range 4-20 yrs)
Toward end of this period, people start developing symptoms like weight loss and fever
About 5% are long term non-progressors
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Outcomes of treatment
Average survival Without treatment:
9-11 yrs after infection of HIV
6-19 months after development of AIDS
Half of infants born with HIV die by age 2
With treatment:
Prospect of a normal lifespan
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New prevention tools: Prep and Pep
Prep: taken daily by people at high risk for acquiring HIV
Pep: Taken ASAP after a possible exposure (within 72 hours)
No FDA approved vaccine at this time. Trials under way.
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Remember the McKeown Hypothesis? —that determinants of health (ie living conditions, sanitation), other than medications are primarily responsible for improvement over time? Is this true for HIV?
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