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Describe the barrier or issue in health care that you want to address for your Capstone Project Paper (two or three sentences): Patient outcomes are the final entity of care, changes in patient behavior, and the patient's health situation as a result of health interventions. ln human health, there has been a new development requiring realizing the best possible patient outcome using the lowest cost and enhancing patient value. ln defining patient care, the only real determinants of quality are the results. When they are reported and measured, it leverages the adoption of best practices and improvements.

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Criteria Article 1 Article 2 Article 3 Article 4 Article 5 Article 6 Author, Journal (Peer-Reviewed), and Permalink or Working Link to Access Article Authors: Goligher, E. C., Brochard, L. J., Reid, W. D., Fan, E., Saarela, O., Slutsky, A. S., ... & Ferguson, N. D. Journal: The Lancet Respiratory Medicine.

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Link: https://sci-hub.st/https://www.sciencedirect.com/science/article/pii/S2213260018303667 Authors: Abidi, M. Z., Hari, P., Chen, M., Kim, S., Battiwala, M., Dahi, P. B., ... & Green, J. Journal: Bone marrow transplantation, The link: https://sci-hub.st/https://www.nature.com/articles/s41409-019-0457-9 Author: Mclntyre, M., Doeltgen, S., Dalton, N., Koppa, M., & Chimunda, T. Journal: Australian Critical Care. Link: https://sci-hub.st/https://www.sciencedirect.com/science/article/pii/S1036731420302320 Author:

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Rottmann, N., Skov, O., Andersen, C. M., Theuns, D. A., & Pedersen, S. S. Journal: Journal of psychosomatic research, Link: https://sci-hub.st/https://www.sciencedirect.com/science/article/pii/S0022399918304161 Author: Sokolova, A., & Smith, S. D. Journal: Australasian Journal of Dermatology, Link: https://sci- hub.st/https://onlinelibrary.wiley.com/doi/abs/10.1111/ajd.12331 Author: Laschinger, H. K. S Journal: JONA: The Journal of Nursing Administration Link: https://sci-hub.st/https://journals.lww.com/jonajournal/FullText/2014/05000/lmpact_of_Workplace_Mistreatme nt_on_Patient_Safety.9.aspx Article Title and Year Published Title: Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure Year of publication: 2019 Article Title: Virus detection in the cerebrospinal fluid of hematopoietic stem cell transplant recipients is associated with poor patient outcomes: a ClBMTR contemporary longitudinal study. Bone marrow transplantation Year: 2019 Article title: Post-extubation dysphagia incidence in critically ill patients: A systematic review and meta- analysis. Year Published:2020 Article Title: Psychological distress in patients with an implantable cardioverter- defibrillator and their partners.

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Journal of psychosomatic research Year Published: 2018 Article title: Factors contributing to poor treatment outcomes in childhood atopic dermatitis. Year Published: 2015 Article Title: lmpact of workplace mistreatment on patient safety risk and nurse-assessed patient outcomes.

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Year Published: 2014 November 5) Research Questions (Qualitative)/Hypothesis (Quantitative), and

Purposes/Aim of Study Research question focusses on Diaphragmatic myotrauma: a mediator of poor patient outcome and prolonged ventilation in acute respiratory failure.

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The main objective is to summarize the evidence for the clinical evidence of how diaphragm muscle injury can result in ventilator over-assistance eccentric contractions, and end-expiratory shortening. The research hypothesis is that allogeneic hematopoietic cell transplant is a curative treatment choice for an extensive range of disorders.

The main objective is to showcase that virus detection in the hematopoietic cell’s cerebrospinal fluid in transplant recipients is related to poor outcomes in patients The research question: Establishing whether persistent Postextubation in critically ill patients can cause poor patient outcomes.

The main objective: Persistent Postextubation can cause poor patient outcomes in critically ill patients. The research question: what are some of the psychological distresses of patients with lCD defibrillator. The research objective is to explore the psychological distress associate with patients with lCD defibrillator The research question: what are some of the factors that contribute to poor-management of post-operative abdominal pain in patients Research Objective: To establish factors contributing to poor-management of post-operative abdominal pain in patients.

The research aimed to investigate the effect of subtle forms of mistreatment at the workplace, such as incivility and bullying on the perceptions of Canadian nurses in the safety risk of patents and the prevalence of adverse events and nurse-assessed quality.

Design (Quantitative, Qualitative, or other) The research design is a retrospective cohort research The study took the form of quantitative research, where data was collected from the ClBMTR working group.

The research design was a metanalysis and systematic review research design. The research design was a quantitative study. A quantitative research design was adopted to help in realizing the objectives of this study.

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The research took the form of a quantitative design where questionnaires were emailed to 336 respondents. Setting/Sample Considerable cohort research of studies of diaphragm biopsy in patients undergoing mechanical ventilation.

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An electronic database search was done to identify research works over 500 transplant centers around the globe. The sample included 8 databases, namely google scholar, MEDLlNE, Embasse, Cochrane Library, Speech BlTE, and databases ClNAHL.

A total of 448 respondents were enrolled out of which 413 had a partner The research relied on five databases. They lnclude; Synergy, Blackwell, Ovid, Pub-Medline, and Google scholar were used.

Three hundred thirty-six nurses from acute care settings located in Ontario were obtained. Methods: lntervention/lnstruments The research conducted a multivariate exploration of risk factors and epidemiology for diaphragm weaknesses during severe illness.

HCT data was collected from CMBTR working group transplant centers around the globe. Using a relevant

search strategy, the research conducted a metanalysis and systematic review of literature from 8 databases.

A retrospective study of consecutively implanted individuals along with their partner filled questionnaires on symptoms of anxiety and social support before lCD implantation. The research methodology was literature- based and involved the use of keywords such as post-operative pain, abdominal pain, painkillers, analgesia, and pain intensity.

The research hypotheses were tested based on data from 336 nurses working in acute care hospitals in Ontario. Analysis The tool employed a mediation analysis in determining the level of interaction and relationship between two variables and outcome and exposure Transplant factors, patients, and disease were statistically reported as medians or frequencies as appropriate.

OpenMeta analysis was used in synthesizing data from the literature sources. Frequency, mean values with SDs, percentages and frequency distributions were computed for sample characteristics The searches were screened to obtain relevant themes for the study. The relevant articles had full-text versions obtained. Data analysis was carried out using the SPSS tool.

Key Findings Monitoring and assessment of respiratory effort should be part of the lCU’s clinical practice routine. HHV-6 is a dominant CNS-V. HHV-6 CNS-V happens during the initial stages of the transplant, and the individuals exposed to CBT are predominant.

Patients likely to showcase signs of PED are those that receive endotracheal intubation when they are critically ill. Symptoms of depression and anxiety had slight improvement for both partner and patients Despite several improvements in anesthesia, analgesia, and delivery techniques, post-operative pain management remains suboptimal in adult patients.

lncivility and bullying from nurses, supervisors, physicians possess significant implications on nurse-assessed outcomes. Recommendations Based on current evidence, nurse practitioners should ensure that they consider patients' respiratory management effort imperative to ensure that they reduce the diaphragm inactivity duration.

There is a need to conduct further studies better explain the clinical outcomes and incidence of non-HHV-6 and HHV-6 associated viral encephalitis. ln a large cohort of severely ill patients, there seems to be paucity of studies on the effect and predominant f PE in critically ill patients with brief exposure to intubation.

To leverage patient care and management, it is essential to adopt a more focused research technique that encompasses standardized and rigorous methodology across research in ensuring that firm conclusions are drawn on the effect of shocks on patient outcomes.

Analgesia should be employed by the clock and in a multimodal fashion based on the needs and requirements of the patient. The research recommends that seemingly simple forms of mistreatment at the workplace can play a significant role in poor patient outcomes since it establishes a sense of higher patient safety.

Explanation of How the Article Supports Your ldentified Barrier or lssue in Health Care The research showcases that the primary effect of myotrauma paradigm is to offer a conceptual model on titrating ventilator support to curb diaphragm injury. lf there is no strong evidence for the neuromuscular blockade, clinicians should generally purpose to maintain an average inspiratory effort level. ln essence, the ate is essential because it showcases ways of minimizing poor patient outcome by reducing transpulmonary pressure applied to the lungs.

The findings of this research function improve physician’s comprehension of the mortality effect of HHV-6 CNS-V and HHV-6 after an immediate HCT. Moreover, HCT patients are highly vulnerable to infections and a high mortality rate. As such, this article ensures that any clinical centers or transplant units need to adhere to protocol and report any consecutive transplants and report follow-ups.

PED is common in patients exposed to endotracheal intubation when they are critically ill. Commonly indicated findings within various research works showcase that PED research for heterogeneity fails to issue reasons for this variation. The research findings indicate an independent correlation between poor patient

outcomes and Postextubation, death, and reintubation.

lCD shock is closely associated with less improvement in depression and anxiety symptoms. Moreover, the findings indicate that symptomatic heart failure and lCD indication was closely connected to fewer improvements in anxiety only. The research does an exemplary job in exploring the psychological distress for lCD patients hence laying a foundation for improving patient outcomes in a hospital setting.

Does an exemplary job in examining the strength of evidence-based secondary and primary prevention trials using life quality as patient outcomes? The article suggests that in general, there is a need for leveraging management of pain in post-operative adults to enhance their safety, recovery, and curb morbidity. As such, issues of the poor patient outcome can be avoided with relevant education coupled with robust guidelines and policies backed by up to date evidence.

Managers possess an instrumental role in establishing environments that provide support to professional nurses focusing on quality patient care. For this reason, the article showcases the need to create a positive patient safety culture to ensure positive outcomes for patients. ln essence, taking concrete, actionable steps to curb negative interpersonal interactions such as incivility and bullying is a crucial phase or step in the process.

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