To test the primary hypothesis of a study, infants were categorized by gestational age and were designated as having a severe disease if they had a concentration of a certain hormone which was 2.6 sd below the mean score for the assay from their specimen

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To test the primary hypothesis of a study, infants were categorized by gestational age and were designated as having a severe disease if they had a concentration of a certain hormone which was 2.6 sd below the mean score for the assay from their specimen. Assume also that these assays are done in batches of 240 specimens and that a mean and sd were calculated for each batch based on a sample size of 240. Children in the study were given a standard mental development test at <30 months of age. The results are shown in the table below:
Severe Disease Mean score +/ sdn

No 106 +/- 21 138
Yes 88 +/- 25 17

a. (15 points) Perform a test to compare the mean score of the developmental test between children with and without the severe disease (report a p-value).( 11.51)
b. (10 points) Suppose that we wanted to use data on children of all gestational ages in the study. Suggest a type of analysis that could be used to relate the score on the developmental test to severe disease while controlling for age. ( suggest an analysis don’t actually do it)(11.52)

 

    • 9 years ago
    To test the primary hypothesis of a study, infants were categorized by gestational age and were designated as having a severe disease if they had a concentration of a certain hormone which was 2.6 sd below the mean score for the assay from their specimen
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