Please help with homework discussion question w2

as example of air pollution, we periodically hear of carbon monoxide fatalities particularly during the winter months, when families are using generators inappropriately during power outages.

A pioneer of industrial toxicology, Alice Hamilton, could have studied cases of carbon monoxide overexposure in the work place.

However, which three historical events in environmental epidemiology have resulted in the most severe health outcomes. What data or statistical evidence do you have to support this with APA formatted sources?  

Where/when did it occur? Did any laws or regulations develop as a result, such as with DDT? Please discuss and be sure to include the APA formatted source that gives veracity to your remarks.