MIS week2 discussion

Most companies would like to be in the market-leading position of JetBlue, Dell, or Walmart, all of which have used Management Information Systems (MIS) to secure their respective spots in the market place.  These companies are relentless about keeping the cost of technology and products down by combining the best of MIS and business leadership.  The future belongs to those organizations perceptive enough to grasp the significance of MIS and resourceful enough to coordinate their business and MIS. 

Using Internet and other resources do some research and answer the question - Why is it challenging for businesses to align MIS and their other operations?  (your answer should be 3-4 paragraphs in length)