describe and discuss method to determine cellular immune response to infectious agent individual

Topic: Describe and discuss a method to determine the cellular immune response to an infectious agent in an individual.

In a 4-5 page paper (text and references ), using double spacing and 12 font print:

1)     Discuss in general how a response to an infectious agent  is determined.

2)     Choose any virus or intracellular bacteria (best choice, Mycobacterium  tuberculosis).

3)     Describe an “in vitro method” to determine either a qualitative or quantitative response in an individual

4)     Mention briefly in your discussion a possible “in vivo” method which can determine if a cellular immune response has occurred.