ORGANIC 2 DISCUSSION 2 RESPONSES

Catarina Smith

B-carotene assits within the body byB-carotene CHY ~ protecting against free radicals and acting as- &

CH3 CH3 P an antioxidant . Free radicals are dangerous ↑ us --z asthey damage cells through oxidation . B- I S 2/ I / carotene can be found in sweet potatoes, carrots,- - I als als↳ Yats des

C3 fruits, carrots a more.

Vitamin E Vitamin E is another antioxidant within our

bodies which can be found in nuts, seeds, veggies,

CH3 He fruits, or plant based oils. Vitamin E also protects

10 ↑ ↑ against free radicals and boost's the immune

/ -- ~↳ I system to fight off bacteria viruses

k Me City - - I

I Lofr CH3

Vitamin C How Vitamin E works ... kp-102 L'->-> chain oxidation it

/= propagation voI 0 Chain ->

I ooH L02 LOOH

↳-> chain oxidation

maininhibition Ma- 2A

NO - LO2 -> chain oxidation

I - ↑Vitamin C is another antioxidant / ↳ Loo- / Kinn-10 / - - which protects against free radicals 1 ko 0 /

I

/ -oand can be found in tomatoes, I P O2 .potatoes, Cauli flower, brocoli , and

/ I

. p - k

↳ ↑ W·more. Vitamins also aids in iron E / - -absorption, boosts the immune system a

(E) I ↳ * in healing wounds/forming scar c , ubiquinol

/ 100 Tissue, and aids in repairing / kn105 dimermaintaining bores, cartilage - teeth.

Retro: Hoye cite BrMg

->Ha cn Teen- No-CH3 - He HrL -> its ->

No Li ii de ↳Hy

synthesis:

kO+BY ~HyC-pCH3 He Hac-->Ins CH3

I-bromo-2-methylbutare 2 bromo-2

2-methylbut-1-ere 2-methylbutane methylbutane

(major product)

-my pryether HO H-

H2SOU Bring

I its-> ↳run -> Fre ren

re- Us ot

- H20

Cry CH3

4-methylhexan-1-01 grighard reagent

mCPBA Hz =CH

oxivant

Vitam Ci

Catso02

Vitamin E:

beta - Carotene

HO

Your Name: hosezinna homero

Ho

Antioxidants typically don't normally involve a typical 2 electron oxidation mechanism that you might expect. What antioxidants typically do is quench frec radicals that form in your body.

1. Investigate and draw the structure (and provide the name) for 3 common antioxidants that are commonly consumed and write a detailed description of how these antioxidants work. Then, provide a mechanism clearly illustrating how one of the antioxidants works.

3 the most commor antoxidants

Vitamn . tamin Eand beta-carotene.

Antioxdants one molecule o thousands of oil

here fore, they

Ho

CHs

OH

CH3

H 7

CH3

s Caven ge and

HO

destroy radicals, According to +he text

a radi�al scavenger Can prevent the autoox1datlon of

molecules by not allouing the chain process to begn. protect the bods aqainst a dicals,

CH3

(antioxi dants) work by firs+ eating them They VtaminC is found in ; kiwi, organes, broccoli, peppers.

C H3 C H3

tr he human body are:

Vitamin C acting as o destroy Vitama C wor ks by decreasine the activity tree radicals, they

radcals by bndergoing hy drogen a bstraction, +ran sferring"'a H-atom+b

+he radieal, thus maki'ng a more Stade yet less reactve radical.

Pound in: pumlzin, peanuts, Spinash, collard 9reens, almonas

antioxi dont

1

tood in: Carrots, eggs, tish, peacheS manGos, Avocados..

ad much more.

2. Radical (mono)halogenation can also be uscful in synthesis as well. Using the carbon sources provided below and any necessary reaction that has been covered in Chapter l0 as well as previous chapters in the text, propose a synthesis of the alkyne product shown below. Show all necessary steps and include the reagents/conditions necded for cach step. Draw the major organic product expected atter cach step as well. Remember, you must use the carbon sources provided and these carbons need to be incorporated into the product shown. You do not need to draw arrow-pushing mechanism for ANY of the steps. To help you with the forward synthesis, also design a viable retrosynthetic scheme that illustrate the key bond disconnects you will utilize in your proposed synthesis.

H -C= C

carbon sources

and

HzC=CH

steps

KoH hect

H2

Linglar

2

NawHe