epidemiological study design

Help me design an approach to investigate vaccine safety by selecting an appropriate epidemiological study design and identifying relevant biostatistical measures.

1. Select one epidemiological study design (e.g., cohort, case-control, randomized controlled trial, cross-sectional) that you believe is best suited to assess vaccine safety.
2. Justify your choice of study design by explaining its strengths for addressing vaccine safety concerns and comparing it to at least two alternative study designs you did not select. Your justification should address feasibility, ethical considerations, and the ability to establish causality.
3. Identify and describe at least two specific biostatistical measures (e.g., relative risk, odds ratio, incidence rate, confidence intervals) that would be appropriate for analyzing data from your chosen study design. Explain how each measure would help you draw conclusions about vaccine safety.

Response will be two pages (not including cover and citations), APA format.