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The Effects of Anti-Cancer Drugs on Cancer Outcomes

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Introduction

Cancer is one of the world most deadly diseases

Scientists have been working to develop cure

Developments made in healthcare determines the quality of life

Different forms of treatment are available

Some work effectively while some have failed (Silaghi et al., 2021)

More research is required to get the antidote

Millions of people worldwide suffer from the disease

Cancer medicine likely to give higher revenue

As more diseases affect humanity, more research needs to be done to avert the situations. During the covid-19 pandemic, scientific research made it possible to develop vaccines and made life easy (Silaghi et al., 2021). Cancer is one of the deadliest diseases that have rocked humanity and adequate research must be conducted to ensure that an appropriate cure is developed.

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Literature Review

Cancer is the main cause of death worldwide

In 2018 alone, it accounted for over 9.5 million death (Meegan & O’Boyle, 2022)

The cancer outcomes have prompted more research for an antidote

Different drugs developed in a quest to cure cancer

Not all have successfully cured and a few have side effects

Evidence on efficacy and safety of medication is needed before it can be used

All anticancer medicine must therefore be double checked for efficacy before use

Cancer has been a life threatening disease and as the prevalence rises, more research is done to ensure that the medicine does not have side effects to the patients. The statistics of 2018 that showed increased number of death sparked many research institutions to develop medication (Meegan & O’Boyle, 2022). However, some of the medicines have had negative side effects and led to other life threatening outcome. Consequently, people were required to offer evidence based outcome on the efficacy before the medication is used.

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Literature Review Cont.

Some patients developed resistance to some of the anti-cancer diseases

The mTOR and NAD are the paths that are responsible for resistance in cancer cell

Future treatment should focus on the pathways (Moreau Bachelard et al., 2021)

The cancer medications were categorized into their levels of cancer

Different therapeutic options have been made available to treat the disease.

The medication resistance mechanism must be known for better research\

Thyroid cancer was found to be treated with a different medication.

As scientists and researchers work to find out ways of overcoming the challenge caused by cancer, different resistance mechanisms were found in the cancer genes (Moreau Bachelard et al., 2021). A cancerous cell that is resistant to the medication is likely to be incurable when treated to the drugs it resist. More tests must therefore be done on individuals before commencing the treatment for the disease.

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Analysis of the literature

One in six women are prone to cancer

For men, one in every five is prone to cancer

Breast cancer and lung cancer are the most prevalence types of the disease

The prevalence of the two diseases accounts for over 23% of all cases (Indini et al., 2022).

Chemotherapy is one of the most effective tool to treat many types of cancers

Other oncology drugs have been used to improve patient’s conditions

All anti-cancer drugs must be tested for resistance and efficacy before they can be used

The analysis of disease using the gender index has proved that more men are at risk compared to women (Indini et al., 2022). Further, the diseases affect the people based on the exposure that the people are made to undergo. Further, lung and breast cancer are the most prevalent types of cancers between men and women respectively and chemotherapy is the best medication that is known to save the population.

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Discussion

Chemotherapy is one of the most used medication

It is however not as appropriate because more healthy cells are killed in the process

Late discovery of the disease makes it difficult to cure

However with advancement in technology encourages many people to undergo early diagnostics

Early treatment is possible to end the disease is the key (Meegan & O’Boyle, 2022)

Awareness and cancer campaigns are key to improve people’s quality of life

Awareness and screening programs must be made possible

As cancer continues to threaten the people in the world, scientist and researchers in the medical domains have improved their research to ensure that people are safe. Although chemotherapy is the best way to treat the disease, it is said that other healthy cells may be affected. It is imperative to note that whenever people are trained and made to screen at early stages, it may be possible to overcome the challenges of cancer (Meegan & O’Boyle, 2022). Governmental programs must ensure that people have all the knowledge required for cancer treatment

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Discussion Cont.

Other than chemotherapy, there are other methods

Minor and major surgeries have been performed for cancer patients

Targeted and immunotherapy are other available options to eliminate the prevalence of cancer.

Hormone therapy and clinical trials are emerging as anticancer medications

Medical practitioners must be equipped to research more on the cancer types and medication

The present medication must be put through some relevant tests

Continuous research on the best antidote is ongoing (Indini et al., 2022).

Although chemotherapy is the main way of treating cancer, there are other medication approved and unapproved to take care of the patients, there are other treatment methods that have been applied. In a nutshell, there are four pillars for the treatment of cancer that makes patients feel better (Indini et al., 2022). The four pillars are surgery where the cancerous cells are removed, radiation therapy where the person feels better. Further, external radionuclide therapy or (ERT) for faster healing.

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Conclusion

Cancer prevalence is on the rise

Different medication have been tested to treat the disease

Screening for early detection is key to save people’s lives

The issue of resistance has been key on the medication

Continuous research must be done on the medication

There are four types of medication

Practitioners must ensure people are made aware of the deadly disease

Cancer is one of the diseases that jeopardize people’s quality of life and requires medication. However, the evolution of the cancerous cells have been changing making them resistant to some medication. When the genes change, scientists should research on the best anticancer medication. Awareness is key to ensure people are safe from the disease since early detection may lead to better treatment.

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References

Indini, A., Fiorilla, I., Ponzone, L., Calautti, E., & Audrito, V. (2022). NAD/NAMPT and mTOR pathways in melanoma: Drivers of drug resistance and prospective therapeutic targets. International Journal of Molecular Sciences, 23(17), 9985. https://doi.org/10.3390/ijms23179985

Meegan, M. J., & O’Boyle, N. M. (2022). Special Issue “Anticancer Drugs 2021”. Pharmaceuticals, 15(4), 479. https://doi.org/10.3390/ph15040479

Moreau Bachelard, C., Coquan, E., du Rusquec, P., Paoletti, X., & Le Tourneau, C. (2021). Risks and benefits of anticancer drugs in advanced cancer patients: A systematic review and meta-analysis. EClinicalMedicine, 40, 101130. https://doi.org/10.1016/j.eclinm.2021.101130

Silaghi, H., Lozovanu, V., Georgescu, C. E., Pop, C., Nasui, B. A., Cătoi, A. F., & Silaghi, C. A. (2022). State of the art in the current management and future directions of targeted therapy for differentiated thyroid cancer. International Journal of Molecular Sciences, 23(7), 3470. https://doi.org/10.3390/ijms23073470

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