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USW1.46926.202030 - NURS-6501N-47,Advanced Pathophysiology.2019 Winter Qtr 11/25-02/16-PT27
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semiloore Akerele
on Sun, Jan 05 2020, 11:10 PM
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Submission ID: cc483e03-4a16-4f88-af7c-19b95d37391f
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Running head: ASTHMA 1
ASTHMA 5
1
Pathophysiological Mechanisms of Chronic and Acute Asthma Exacerbation
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Pathophysiological Mechanisms of Chronic and Acute Asthma Exacerbation
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Pathophysiological Mechanisms of Chronic Asthma and Acute Asthma Exacerbation
Semiloore Akerele
Walden University: NURS-6051N
January 5th , 2020
1
Pathophysiological mechanisms of chronic and acute asthma exacerbation
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Pathophysiological mechanisms of chronic and acute asthma exacerbation
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Pathophysiological Mechanisms of Chronic Asthma and Acute Asthma Exacerbation
Asthma refers to conditions that affect pulmonary.
2
It might result in either acute or chronic inflammation of respiratory
tubes and tightening of the respiratory tract smooth muscles.
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It might result in
either acute or chronic inflammation of respiratory tubes and tightening
of the respiratory tract smooth muscles
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Asthma is a pulmonary condition that results in either a
chronic or an acute inflammation of the respiratory tubes coupled with a
tightening of the smooth muscles of the respiratory tract
3
The pathophysiological mechanism of exacerbating acute and chronic
cancer is similar to the etiological aspects of persistent chlamydia and
viruses.
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The pathophysiological
mechanism of exacerbating acute and chronic cancer is similar to the
etiological aspects of persistent chlamydia and viruses
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The pathophysiological exacerbation of chronic asthma is
closely related to the etiological aspects of persistent viruses and
chlamydia
4
Therefore, realizing the pathophysiological mechanism of each type of
asthma is critical in determining diagnosis, exacerbation, and
prescription of its treatment.
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Therefore, realizing
the pathophysiological mechanism of each type of asthma is critical in
determining diagnosis, exacerbation, and prescription of its treatment
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Establishing the pathophysiological mechanism of each
asthma is an important step in determining its exacerbation, diagnosis
and prescribing treatment for the patient
For asthma to grow, viruses and other organisms play vital roles.
5
In exacerbation, the key mechanism is viral replication resulting in the
epithelial cells of the respiratory tract which triggers inflammation,
cytokine release, thus resulting in the production of a large amount of
mucus.
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In exacerbation, the
key mechanism is viral replication resulting in the epithelial cells of
the respiratory tract which triggers inflammation, cytokine release,
thus resulting in the production of a large amount of mucus
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The key mechanism in this exacerbation is the viral
replication that results in the epithelial cells of the respiratory
tract triggering cytokine release, inflammation, and the final large
mucus production
6
However, chlamydia and virus do not lead to changes in arterial blood patterns (Durham et al.
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However, chlamydia and virus do not lead to changes in arterial blood patterns (Durham et al
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Nevertheless, chlamydia and virus do not lead to the sporadic changes in arterial blood patterns
2016).
During exacerbation of asthma,
dehydration plays a vital role because it has a close relation to the
water levels in the body with regards to epithelial cells' airway.
4
Nakagome and Nagata (2011), states that during asthma attack through
dehydration, the arterial blood patterns exhibit very sharp changes in
the blood PH which could rise to as high as 7.60 while the blood PaO2
reduces to very low levels within a short time as low as 40 mm Hg
coupled with a sharp rise in PaCO2.
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Nakagome and Nagata
(2011), states that during asthma attack through dehydration, the
arterial blood patterns exhibit very sharp changes in the blood PH which
could rise to as high as 7.60 while the blood PaO2 reduces to very low
levels within a short time as low as 40 mm Hg coupled with a sharp rise
in PaCO2
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According to Walsh, Sills and Arnold (2017), during asthma
attack through dehydration, the arterial blood patterns exhibit very
sharp changes in the blood PH which could rise to as high as 7.60 while
the blood PaO2 reduces to very low levels within a short time as low as
40 mm Hg coupled with a sharp rise in PaCO2
6
The period of emotional grief, stress, and sorrow also trigger acute asthma symptoms during exacerbation.
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The period of emotional grief, stress, and sorrow also trigger acute asthma symptoms during exacerbation
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Emotional stress, sorrow, and grief may also trigger acute asthma exacerbation
In such cases, levels of oxygen drop very fast making a patient lose
inner breathe instantly thus raising their CO2 levels alongside the PH
levels with almost the same levels.
4
In case of intense emotions, patients bring out asthma symptoms such as
shortened breath, increased respiratory resistance, and decreased peak
of expiratory flow rates.
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In case of intense
emotions, patients bring out asthma symptoms such as shortened breath,
increased respiratory resistance, and decreased peak of expiratory flow
rates
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Conversely, having intense emotions brings out asthma
symptoms such as airway reactivity, decreased peak expiratory flow rate,
increased respiratory resistance and shortness of breath
The factor I selected is allergic
regardless of its being a predominant multifactorial condition. In most
cases, asthma exacerbation speeds where there is a chronic or strong
family history of allergic reactions. It means the allergy effect is
triggered by immunological responses factor in the symptomatology of
asthma. Therefore, this factor impacts the pathophysiology of both
disorders by disrupting the normal epithelial cells leading to the
trigger of a response explaining the common occurring allergies in
response to the inhalant antigens.
7
Chronic asthma is also exacerbated in the respiratory tract as a result
of exposure to metal toxicity such as aluminium, copper, Cadmium, and
Zinc.
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Chronic asthma is also
exacerbated in the respiratory tract as a result of exposure to metal
toxicity such as aluminium, copper, Cadmium, and Zinc
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Exposure to metal toxicity, especially as a result of
inhalation, also causes the respiratory tract to exacerbate to chronic
Asthma
Metals raise the PH and the CO2 content in the blood rises up thus reducing oxygen (D’Amato, 2011).
8
All the mentioned factors have widespread effects on the pathophysiological disorders present in asthma.
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All the mentioned factors have widespread effects on the pathophysiological disorders present in asthma
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The factors mentioned above have widespread effects on the pathophysiological disorders present in asthma
5
The diagnosis of asthma follows a special approach as established by exacerbation.
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The diagnosis of asthma follows a special approach as established by exacerbation
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The diagnosis of asthma follows a particular approach, as established by its exacerbation
If a patient is suspected of asthma the doctor performs an allergic test.
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In this case, breathing and medical history tests are done to determine how well their lungs are working.
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In this case, breathing and medical history tests are done to determine how well their lungs are working
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During this period, medical history and breathing tests are performed establishing how well a patient’s lungs are working
9
Up to date asthma have no definite cure, therefore if an individual is
realized with it, an allergist can recommend they take medications that
avoid asthma triggers.
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Up to date asthma have
no definite cure, therefore if an individual is realized with it, an
allergist can recommend they take medications that avoid asthma triggers
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Even if there is no cure for asthma, the allergist will recommend taking medications that avoid asthma triggers
Prescriptions such as corticosteroids are recommended to be taken on a
daily basis. In case the dehydration test is involved and finds the
patient's water level is below the required level taking more water to
boost it is recommended.
5
For the case of toxic metals, body fluids and solids are tested for any
presence of toxic substances in the body including bloodstream thus
recommendation of heavy detoxification.
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For the case of toxic
metals, body fluids and solids are tested for any presence of toxic
substances in the body including bloodstream thus recommendation of
heavy detoxification
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For the case of metal toxicity, body fluids and solids are
tested for any presence of toxic substances in the body, including the
bloodstream
Finally, in the case of chlamydia and virus, a test is done through
epistemological tests. If established positively antibiotics are given
to attack them, thus reducing asthma.
10
Acute asthma mind mapAcute asthma Diagnosis Treatment
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Acute asthma mind mapAcute asthma Diagnosis Treatment
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( Diagnosis ) ( Treatment ) ( Acute asthma )Acute asthma mind map
Emotional stress
Therapy
Clinical presentation
Epistemology
Corticosteroids daily
Anxiety
Dehydration
Briefing tests Depression an
Water addition
Pathophysiological
8
Disruption of epithelial cells
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Disruption of epithelial cells
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Disruption of epithelial cells
Pulmonary fibrosis
8
Chronic asthma mind map.
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Chronic asthma mind map
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Chronic asthma mind map
Detoxification Viruses and chlamydia
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Detoxification Viruses and chlamydia
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Detoxification Viruses and chlamydia
Antibiotics Treatment Allergies
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Antibiotics Treatment Allergies
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Antibiotics Treatment Allergies
Lung infection Disruption of epithelial cells
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Lung infection Disruption of epithelial cells
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Lung infection Disruption of epithelial cells
Working lungs
Mucus production
8
Inflammation Medical history
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Inflammation Medical history
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Inflammation Medical history
Clinical presentation Pathophysiology Epistemology Diagnosis Metal toxicity
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Clinical presentation Pathophysiology Epistemology Diagnosis Metal toxicity
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Clinical presentation Pathophysiology Epistemology Diagnosis Metal toxicity
Chronic asthma
References
D'Amato, G. (2011).
11
Effects of climatic changes and urban air pollution on the rising trends of respiratory allergy and asthma.
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Effects of climatic changes and urban air pollution on the rising trends of respiratory allergy and asthma
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Effects of climatic changes and urban air pollution on the rising trends of respiratory allergy and asthma
Multidisciplinary respiratory medicine, 6(1), 28.
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Multidisciplinary respiratory medicine, 6(1), 28
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Multidisciplinary Respiratory Medicine, 6(1), 28–37
Durham, A.
12
L., Caramori, G., Chung, K.
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L., Caramori, G., Chung, K
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L., Caramori, G., Chung, K
F., & Adcock, I.
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F., & Adcock, I
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F., & Adcock, I
M. (2016).
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Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease.
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Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease
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Targeted Anti-Inflammatory Therapeutics in Asthma and Chronic Obstructive Lung Disease
13
Translational Research, 167(1), 192-203.
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Translational Research, 167(1), 192-203
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Translational Research, 167(1), 192-203
Nakagome, K., & Nagata, M. (2011).
Pathogenesis of airway inflammation in bronchial asthma. Auris Nasus
Larynx, 38(5), 555-563.