GrantProposal14.pdf

Creating Memories through Sense of Smell for Dementia

Aminata Sillah

Sillaham@kean.edu

March 4, 2021

Introduction

Memories are sparked by everything we smell. Memories are created from our childhood,

teenage years and adulthood. Researchers are figuring out that “sniffing out,” close relations

between losing the sense of smell and the parallel of memory loss related with dementia

(Intriago, 2016). Sense of smell is recognized as olfactory sense. Olfactory memory is the

remembrance of smells. Olfactory memory is a simple operation of the brain; however, its role is

complex in both conscious and subconscious memory (Intriago, 2016). The other senses pass

through a different brain region before being operated. Sense of smell, olfactory cortex is looped

right to the amygdala and hippocampus – major key to the limbic system (Intriago, 2016). The

things we smelled throughout the years stays with us. Those smells become part of our emotional

memories and can recover through the form of emotional acknowledgments. Certain scents bring

back long- term memories through emotional response which will be a great treatment impact on

dementia including Alzheimer's disease.

According to El Haj and Giachet (2016), autobiographical memory is known to contain

all personal memories that is comparable to whom we are, were discovered to be damaged in

Alzheimer’s disease. Autobiographical memory is known for being the key part of our memory

system which allows repairs and maintenance of self-awareness, self-image, and personal

knowledge and able to retreat past events from our lives (El Haj and Giachet, 2016). People with

Alzheimer’s disease autobiographical memory are declined and it is difficult for them to relive

past events of their lives. Studies tried to reduce the damage of autobiographical memory by

centering sensory signals. Studies also shown that music and odor are powerful benefactors of

involuntary recovery by shrinking the time it will take to recover the memories. Involuntary

autobiographical memories are conscious memories of events of one's life and those memories

comes to the mind suddenly. Olfactory signals are connected memory and emotions which are

amygdala and hippocampus. Neuroimaging studies shows that odor-evoked memories are

distinguish by the brain areas activation that are associated with memory recovery and the cortex

process of olfactory and recruit the brain regions that were operated during visual imagery and

emotions (El Haj and Giachet, 2016).

El Haj, Gandolphe, Gallouj, Kapogiannis and Antoine (2017) presented a case study of

28 participants that were in the mild stage of Alzheimer’s disease and 30 healthy participants that

were the controls. The Alzheimer’s disease participants were enrolled from retirement homes

and diagnosed with Alzheimer’s disease dementia by a neurologist/geriatrician based on the

clinical criteria from the National Institute on Aging-Alzheimer's Association. The control

participants were independent, lived own their own in their homes and lived with a spouse or

relative of Alzheimer’s disease participants. Each participant was tested separately in three

sessions: after odor exposure, after music exposure and in a control condition. They were given

three minutes to describe their memories and they were informed of this time limit in order for

them to structure their memories accordingly and avoiding bias from distractions. Small bottle of

essential oils was opened and participants had to smell the scents with their eyes closed and were

asked to explain the memory that popped in their mind. Two pieces of music was played for the

participants and they had to recall a memory. However, control participants, were told in silence

with odor free air. The outcome of memories being recovered after odor and music exposure in

Alzheimer’s disease participants had a higher precision, emotional experience, mental time travel

and shorter comeback time than the control condition.

Researchers inquired whether the exposure would improve difficulties that recover

memories in Alzheimer’s disease patients. Twenty- six patients with mild Alzheimer’s disease

and 28 healthy control patients were tested to recover childhood, adulthood and current

memories without odor and after odor exposure (El Haj, Gallouj, Glachet, and Moustafa, 2019).

The outcome of this study showed Alzheimer’s disease patients had a higher number and more

certain childhood, adulthood and current memories after odor exposure than without odor.

The olfactory bulb is the first area that is affected in Parkinson’s and Alzheimer’s

diseases. The sense of smell is weaker in early stages of people with these diseases. Correlating

with different activities with different scents help reduce confusion for dementia people with

what is going on. The scents can be essential oils, toast, coffee in the mornings or loved one’s

favorite perfume or aftershave (Bowles, 2007). Same aroma every night before bed for someone

with dementia and Alzheimer’s disease is helpful due to helping them settle for bed. Rosemary,

peppermint, lemon scents are not a good smell to help someone with dementia or Alzheimer’s

disease.

Essential oils are part of aromatherapy which is good for people with dementia including

Alzheimer’s disease. There are multiple essential oils that are effective in treating Alzheimer’s

disease and dementia symptoms through smelling and rubbing into skin. Lavender smells are

calming and balance strong emotions. Lemon balm are very effective and beneficial to people

with Alzheimer’s disease and dementia. Lemon balm are very effective and beneficial to people

with Alzheimer’s disease and dementia. Peppermint stimulates the mind and calm nerves and

corrects absent-mind. Rosemary oils improves cognitive performance, stimulates mind and body

(Best-alzheimers-products.com, 2010). Essential oils trigger certain memories for dementia

including Alzheimer's disease.

The purpose of my proposal is to further investigate the extent to which scent memory

can be used as a means to assist memory recall in persons with dementia. If memories can be

sparked by scents, then persons with dementia including Alzheimer's disease may be triggered to

recall certain memories when undergoing scent training.

Word Cited

El Haj M, Gandolphe MC, Gallouj K, Kapogiannis D, Antoine P. 2017. From nose to memory:

The involuntary nature of odor-evoked autobiographical memories in Alzheimer’s disease. Chem

Senses. 43(1):27–34.

Glachet O, El Haj M. 2019. Emotional and phenomenological properties of odor-evoked

autobiographical memories in Alzheimer’s Disease. Brain Sci. 9(6):135.

Glachet O, Moustafa AA, Gallouj K, El Haj M. 2019. Smell your memories: Positive effect of

odor exposure on recent and remote autobiographical memories in Alzheimer’s disease. J Clin

Exp Neuropsychol. 41(6):555–564.

Joy Bowles BSc. E. 2007 Mar 8. Remember that Smell - Dementia Care International.

Dementiacareinternational.com. https://dementiacareinternational.com/2007/03/remember-that-

smell/.

Olfactory stimulation for Alzheimer’s and dementia. 2010 Jan 6. Best-alzheimers-products.com.

https://best-alzheimers-products.com/olfactory-stimulation.html.

Intriago J. The connection between smells and memory. Seniorsmatter.com. 2016 Apr 25.

https://www.seniorsmatter.com/connection-smells-memory/2492233