please see attached

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MRS. Z CASE STUDY

Q.n1

Ulcerative colitis is an inflammatory bowel illness that causes the colon and rectum of the

patient to become inflamed and ulcerated for an extended period (Kamat et al., 2017). The

symptoms of ulcerative colitis are evident in Mrs. Z. Abdominal aches, exhaustion, and bloody

diarrhea is among these symptoms. Consequently, the pharmacological treatment for Mrs. Z will

be as follows: "Mesalamine 800mg TID for 6/52 weeks, Azathioprine 50mg TID for 2/5 weeks,

and Metronidazole 500mg TID for 5/7 days" (Kamat et al., 2017).

The goal of treatment is to reduce inflammation while also removing the source of it. As

an anti-inflammatory, Mesalamine is useful in treating inflammation in the gastrointestinal tract,

particularly in the colon and rectum. Because it inhibits the inflammatory immune responses

caused by the molecules in the colon's lining, Azathioprine is classified as an immunosuppressive

medicine (Ryan et al., 2020). As a result, the inflammation will be reduced, and the patient will no

longer have discomfort in the abdomen. Finally, metronidazole is an antibiotic that aids in

eradicating colonic bacterial infection.

Qn 2.

A critical part of figuring out how medications affect Mrs. Z is evaluating how well they

work after giving them to her. The relief of the patient's symptoms is one of the medication

therapy's good benefits. Mrs. Z's symptoms of discomfort, fever, and diarrhea should go away in

2 to 5 days if she takes her medication as prescribed. First, I'll take her temperature, examine her

stool, and inquire about her stomach discomfort levels to see if the clinical signs and symptoms

have improved.

3

“The patient’s temperature will decreased from 100.1F to 36-37 degrees Celsius, her stool

will be solid” (Ryan,et al., 2017). the patient’s stomach pain will be at a minimal level if this

assessment demonstrates a positive outcome. Having a favorable result indicates that the

medication being given to Mrs. Z is working. This suggests that the indications and symptoms are

still present and that medication is ineffective at controlling them.

Second, I'll look at the lab results to see if the meds are working. "It's expected that the

white blood cell count will return to normal levels (4,000 to 11,000 WBCs per microliter) and that

the hemoglobin level will rise between 12 to 15.4 g/dl" (Ryan et al., 2020). For Mrs. Z's sake, I'll

look at any potential side effects caused by the medication. There must be a change in medication

if the patient is experiencing hazardous side effects.

Question 3

Mesalamine, metronidazole, and Azathioprine have the potential to cause side effects, and

I'd be happy to inform Mrs. Z of those risks. Nausea, flatulence, weakness, headache, dizziness,

and a rash are some of these side effects (Schirmer et al., 2017). This will help her mentally prepare

for the effects of the medication. In addition, she'll be able to spot any additional potentially

hazardous side effects of the medication. To maximize the effectiveness of the medication, I will

also teach her about the significance of adhering to prescribed dosages. To successfully treat

ulcerative colitis, patients must adhere to their medication regimens.

Qn 4.

Individuals respond differently to a drug's therapeutic and harmful effects because of

genetic differences. Due to a patient's metabolic rate and the amount of drugs in their system,

patients with a sluggish metabolism are more likely to have negative side effects (Schirmer et al.,