bio lab report
Cannabis Science
Gene Neofunctionalization
Duplicates evolve different functions
Interaction 1
Catalytic 1
Interaction 1
Catalytic 2
Interaction 1
Catalytic 1
Mutation affecting amino acids in enzyme’s active site
3
Onofri et al. (2014) Phytochemistry
CBDAS
THCAS
CBDAS
Psychoactive
Appetite stimulator
Analgesic
Non-psychoactive
Anticonvulsant
Anxiolytic
Also present in hops (Humulus lupulus)
Padgitt-Cobb et al. (2019) bioRxiv
Synthase Genes
Cannabinol
4
Cannabinoid Receptors
Endocannabinoid System Helps Maintain Homeostasis
Insects do not have CB1 or CB2 Homologs