stats importatnt

lolo1339
3.pdf

Doctors’ understanding of palliative care Barbara Hanratty Division of Public Health, University of Liverpool, Liverpool, Derek Hibbert Division

of Primary Care, University of Liverpool, Liverpool, Frances Mair Department of General Practice and Primary

Care, University of Glasgow, Glasgow, Carl May Centre for Health Services Research, University of Newcastle

upon Tyne, Newcastle upon Tyne, Chris Ward Cardiologist, Dundee (formerly of Wythenshawe Hospital,

Manchester), Ged Corcoran University Hospital Aintree, Liverpool, Simon Capewell Division of Public Health,

University of Liverpool, Liverpool and Andrea Litva Division of Primary Care, University of Liverpool, Liverpool

Palliative care has been challenged to share its message with a wider audience, and for

many years it has been articulating an approach that is suitable for all patients. However, it

is not clear how widely this message has been accepted. As part of a study into end-of-life

care for heart failure, we conducted seven focus groups with doctors in general practice,

palliative medicine, cardiology, geriatrics and general medicine. In these, we explored

doctors’ understanding of palliative care. Participants displayed a reasonable grasp of

the wider concept of palliative care, but the specialists’ role was ill-defined, reflected

in scepticism about their place outside of cancer. Perceptions of palliative care fell into

three broad areas: it was more than a service, about managing dying, and the concern of

nurses, rather than doctors. Palliative care was welcomed as providing permission to fail,

whilst representing a dilemma between quantity and quality of life for the interviewees. Our

work suggests that specialist palliative care has been partially successful in getting their

message across, and poor understanding or receptivity are not major barriers to

implementing palliative care. Educational or other interventions to implement change in

palliative care need to acknowledge the complex interaction of factors influencing

physicians’ behaviour. Palliative Medicine 2006; 20: 493�497

Key words: knowledge attitudes practice; palliative care; qualitative research

Introduction

Palliative care has been challenged to share its message

with a wider audience,1 and through education and

example, its proponents have been working to improve

care for the majority for nearly 40 years. However,

despite the rapid growth of specialist palliative services

and ideas, it is still widely held that care of the dying is

poor, particularly in hospitals.2�4 The approach espoused

by the hospice movement is potentially relevant to every

area of medicine,5 and the key to improving health

care of the dying must lie in mainstream services.

Specialist palliative care services see only a small

minority of dying patients, most of whom have cancer.6

In other diagnostic groups, such as respiratory and

cardiac disease, patients’ needs for care and support

often go unmet.7,8 As the debate over widening the

responsibilities of the specialist services continues, it is

timely to stop and consider what doctors, in general,

understand by palliative care.

Previous investigations into doctors’ perceptions of

palliative care have often focussed on exploring choice of

topics for educational interventions or testing knowl-

edge.9,10 We know much less about how palliative care is

interpreted or conceptualized.11 This is important, as

acquiring knowledge is only one step towards changing

practice. The influence of different factors on the

complex path between education and behavioural change

is increasingly recognized as important.12,13 Awareness of

doctors’ beliefs, for example, is thought to be crucial.14

The hospital is a particularly important setting. Al-

most half of the UK population die in hospital,15 and

popular belief holds that hospital practitioners may be

more reluctant than their community colleagues to adopt

holistic approaches to care.

We conducted a series of seven focus groups with

doctors, exploring views on the care of people dying with

heart failure. Heart failure is typical of chronic progres-

sive diseases in that a range of specialities may be

involved in patient management. Thus, our participants

from general practice, palliative medicine, geriatrics,

cardiology and general medicine form a cross-section of

hospital and community doctors involved in chronic care.

In this paper, we aim to provide essential baseline

information for the future development of services and

a palliative care approach, by reporting on doctors’

Address for correspondence: Barbara Hanratty, MRC Special Training Fellow, Division of Public Health, University of Liverpool, Whelan Building, Brownlow Hill, Liverpool, L69 3GB, UK. E-mail: b.hanratty@liverpool.ac.uk

Palliative Medicine 2006; 20: 493�497

# 2006 Edward Arnold (Publishers) Ltd 10.1191/0269216306pm1162oa

understanding of palliative care, as expressed during the

focus group discussions.

Methods

We conducted seven focus groups with doctors expected

to have a role in the care of patients with heart failure.

The participants were drawn from one NHS region in England, and recruited via professional bodies or direct

approaches. The groups ranged in size from four to six

doctors (five general practitioners (GPs), five academic

GPs, five district general cardiologists, five tertiary centre

cardiologists, six geriatricians, six palliative care physi-

cians, four general physicians). Each group consisted of

doctors working at consultant level in the same speciality

to maximize openness and facilitate relaxed discussion. Apart from the general physicians, half of whom were

women, there was only one female doctor in each of the

group of GPs, cardiologists and geriatricians, and one

male doctor in the palliative care group. Data to address

doctors’ understanding of palliative care were derived

from the opening question (Can you tell me what you

understand by palliative care?) and all other direct or

implied references to palliative care during the discus- sion. The main focus of the discussion was on the

doctors’ perceptions of the need for palliative care for

patients with heart failure, and what form that does and

should take. The discussion thus encompassed both the

theoretical and practical aspects of palliative care, and

allowed the participants to elaborate their understanding

of palliative care throughout.

Two researchers were present at all the groups, one to facilitate and one to observe. The meetings were recorded

and transcribed and QSR Nvivo software was used for

data management.16 Data analysis used the principles of

constant comparison,17 with two researchers coding and

categorizing all the transcripts. Themes were identified

independently, and discrepancies discussed. Preliminary

results were reviewed and discussed by the multi-

disciplinary group of authors. The focus of this analysis was on the doctors who were not specialists in palliative

care, and data from the specialists’ discussion were used

to compare and contrast with the non-specialist view-

point.

Results

Discussion was lively in all the groups except the meeting

of general physicians. We cannot be certain of the reasons

for this. This group was the most difficult to arrange,

which raises questions as to the salience of the topic for

these doctors. Hierarchical relations within the group

may also have dampened the discussion, and holding the

meeting at lunchtime meant that the pressures of work

were not far away. The specific findings are presented in

terms of the main themes arising from the discussion. This is not meant to imply that all the doctors shared one

view. Development and refining of ideas was apparent

throughout the interviews.

Much more than a service

It was clear from the way that participants referred to

palliative care that it was conceived as much more than a service. Terms, such as ‘mode’, ‘concept’ and ‘situation’,

were used when discussing palliative care. Some framed

their talk in aspirational terms, referring to their ideal as

‘proper palliative care’, or ‘a thorough palliative care

approach’. The appropriateness of palliative care was

not questioned, and even when the group did not

share definitions, they were united in their support of

palliative care as an ideal. There was also a strong sense of the holistic aspects of palliative care throughout the

groups.

I think in a perfect world you see it as a holistic ideal,

encompassing the patient, their family and the pro-

blems the patient has, the problems the family has erm

and both of their expectations of the process that

they’re going through. That would be an ideal world. (GP 1/3)

The importance of looking at the whole picture including

psychosocial issues was expressed in most groups. GPs

and cardiologists also discussed the spiritual aspects of

care, though there was no particular indication that they

felt it was relevant to their work. Communication with

patients and carers was also acknowledged as a major aspect of palliative care.

I think. . . it’s a kind of cultural recognition of whats

death. And, like you were talking about, there didn’t

used to be palliative specialists, I think there were

often priests that would help. (GP 2/1)

Erm I think palliative care depends on patients and

their carers, certainly in cancer but also in heart

failure, understanding the condition, the terminal

nature of their condition, and what we’re trying to

do for them. (Cardiologist 4)

Palliative care was also portrayed as a phase in time,

when the goals of medical management change and death is recognized. It was only through discussion in the

groups that the difficulties of recognizing the right time

to switch to palliative care surfaced as a major challenge.

A change of gear, a diagnosis of dying, switching from

erm officiously striving to keep someone alive er, to

where the main emphasis should be on comfort.

(Geriatrician 3)

494 B Hanratty et al.

Managing dying

The management of dying was an underlying theme in

much of the discussion. Participants drew a picture of

themselves as conductors of the services around their

patients, co-ordinating and facilitating. For some, this

encompassed the environment and the social context, as

well as the medical care. The geriatricians’ discussion

suggested that they felt that they should strive to manage the death, whilst the cardiologists were honest in acknow-

ledging that they made this switch late in the illness.

I think what you’re trying to do with palliative care is

provide the sort of psychological, social support to

relatives and patients and to hopefully have a co-

ordinated approach so it doesn’t collapse at the

weekends, things like that. (GP 1/1)

It’s a co-existent approach, so you keep optimizing,

keep revising the treatment and balancing the combi-

nation. But then you are also aware of the other

factors that are coming in and you also then get a

picture in your mind that is a road to deterioration.

And yes we might stop hammering the ACE inhibitors because they’re clearly not effective and we may be

bringing them something else for the symptoms, but

you’re still maintaining that approach. (Geriatrician 4)

It was only amongst the general physicians that some-

thing closer to the concept of ‘palliative care from

diagnosis’ was discussed. Guidance and pathways for

managing the final 48 hours of life were considered valuable, but only a part of palliative care.

Not very medical

The role of the nurse was emphasized strongly by most

groups, and there was a parallel perception that palliative

care was not necessarily the province of the doctor. It was

‘not very medical’, and ‘largely nursing based care for

people who are terminal’. There seemed to be a complex

set of conflicting motives here. Firstly, it was apparent that palliative care was perceived as being time consum-

ing, and time was openly prized by many of the doctors.

Secondly, palliative care was seen as straightforward

medical practice, and in the words of one of the

consultants in palliative medicine, was ‘not glamorous’.

If the status of doctors is enhanced by displays of

expertize and technical knowledge, palliative care offers

a burden with no return. Labelling palliative care as the role of the nurse perhaps legitimizes the doctor’s choice

not to become involved. However, the concept of

palliative care as an ideal was pervasive in the groups,

and some participants were clearly ambivalent about the

role they played. The presentation of the nurse as having

the skills and the time to provide better care for the dying

may well have been a direct and pragmatic response to

the time constraints of their own jobs.

Quantity versus quality

Many of the treatments for heart failure address both

symptoms and survival, so the switch from rescue to comfort may not be clear-cut. Some of our participants

appeared to confuse the introduction of palliative care

with a direct path to death and focus entirely on quality

of life. Palliative care was described by one geriatrician as

‘quite negatively focussed in terms of survival’. The idea

that different approaches may co-exist, with shades of

grey in patient management, had not been universally

adopted.

The role of the specialist

Neither the GPs nor the hospital doctors expressed clear ideas of how palliative medicine should contribute to

heart failure care. A number had unsuccessfully tried to

refer patients to their local specialist service, and were

disparaging about the narrow remit of the specialist

palliative care service. However, the strongest emotion

was expressed by some of the GPs and geriatricians, who

were keen not to hand over their patients to another

specialty.

After all you know the mortality of life is 100%,

everybody is dying, so what is the difference between

palliative care and good medical practice? You know

there are textbooks of palliative care and there are

palliative care ‘specialists’, why palliative care, why not

just an ordinary doctor? Its sort of a speciality driven by prognosis rather than anything else, because there

are lots of chronic disease that we look after that we

can’t cure they don’t come under the umbrella of

palliative care � diabetes for example. (GP 1/3)

A few individuals described examples of successfully

using advice from their local consultants, but others felt

that palliative care physicians may not have the expertize that they had to deal with heart failure. The palliative

care doctors’ vision of themselves as educating health

professionals to provide most of the support had, on the

whole, not been embraced by the other doctors. The

general physicians acknowledged that there was ‘a lot of

specialism in palliative care already that we don’t really

use sufficiently. . .’ (General Physician 1/4), and their

communication skills were highlighted in particular.

Permission to fail

The cardiologists were frank in admitting their dislike of failure, which was how they perceived the death of a

patient. In other groups, failure was not always articu-

lated, but it was apparent as they described struggling to

find the right words for relatives, the limited time they

had for dying patients on ward rounds and the difficulty

of accurate prognostication. The palliative care physi-

cians were widely admired for having the ability to ‘fail

well’. The introduction of the specialty appeared to be a

Doctors’ understanding of palliative care 495

relief for some doctors, and permission to let go.

However, a number of doctors in different specialities

were concerned at the message this sent to the patients, and one described the attention from specialists as

‘ghoulish’.

The specialists’ view

Discussion amongst the consultants in palliative medi-

cine displayed a shared clarity over their own role in

patient care, as advisors, educators, and expert resources,

there to take a holistic view. Their experience of confu-

sion, ignorance and misperceptions about their role from non-specialist doctors supported much of what had been

said in the other groups. The concept of looking at

palliative care patients ‘with the right eyes’ was how one

participant eloquently described the way in which they

wished to promote a different perspective on patient care.

Respect for the skills of the other specialties pervaded the

discussion, and a willingness to take some responsibility

for any uncertainty that surrounds their role.

But unless you have the right eyes to actually identify

what can be done within that generalist setting. . . there

is a lot of ignorance around about what can be done.

(Palliative Care Physician 3)

I think primary care can be very uncertain about when

to refer to specialist palliative care. . . a lot of it is our

fault, because we could all reel off the WHO definition

and the Calman Hine definition. . . but we’re not very

good at marketing and making it clear as to when we

get involved. (Palliative Care Physician 1)

That doesn’t mean we’ve got all the knowledge and

they need all the teaching. . . its working as a team and

learning how best to get things done. (Palliative Care

Physician 6)

Discussion

Our study participants displayed an understanding of the

wider concept of palliative care, but relatively poor grasp

of the role of the specialist in palliative medicine, and

scepticism about their role beyond cancer. There was also

a strong perception that palliative care is the province of

nurses rather than doctors. The other area of uniformity

across the groups was a feeling that palliative care was something important, even though some of the non-

specialists had had difficulty in coming to an under-

standing of how all the health professionals fitted in, and

had some uncertainty about what it meant in practice.

Differences between the specialties were more clear-cut.

The GPs and geriatricians were generally familiar with

talking about death, appeared to be the most receptive to

the concepts of palliative care. The cardiologists and

physicians were less comfortable with the death of

patients, perhaps because it ill fits their perception of

their role and the day-to-day orientation of their practice. They welcomed the practical help of the specialists.

Limitations

The themes described here offer a unique insight into

doctors’ understanding of palliative care, and raise issues

for further research. However, we acknowledge that our participants’ views may not be typical. With the excep-

tion of the GPs who received locum payments, they were

not rewarded for their involvement. The extent to which

the views offered provide an accurate picture of physi-

cians’ practice is unknown, and the use of standard

definitions by some participants to describe palliative

care may reflect a willingness to conform to accepted

norms. By combining responses to a direct question with implied and direct references throughout the discussions,

we have tried to overcome this potential limitation. At

times, the term ‘palliative care’ was used by interviewees

to refer to specialist services and, elsewhere, to a

palliative care approach. Which of these meanings was

being used was usually clear from the context of the

discussion. In general, we chose not to interrupt the flow

of discussion by stopping repeatedly for clarification. The focus groups consisted of single speciality groups;

either all GPs, or all doctors from one hospital speciality.

The advantages of this approach were that the partici-

pants had a shared understanding of each other’s work.

In many cases, they already knew each other, which

helped to overcome some of the barriers to free-flowing

conversation often found in the initial stages of focus

groups. Single speciality groups also helped minimize the potential for disruptive power relations between the

interviewees. Had the groups been mixed between GPs

and consultants, it is possible that perceptions of a higher

status amongst hospital doctors may have prevented their

GP colleagues from expressing themselves honestly.

Potential disadvantages of not mixing the specialities

included the possibility that the interviewees would have

a uniform view on some issues, and there would be few challenging voices. Conforming to group norms could be

especially evident amongst what is an inherently con-

servative group.

Implications

Our participants were familiar with the concepts of palliative care. Their thoughtful discussion of the holistic

aspects of care of the dying suggests that a lack of

knowledge would not prevent them from delivering good

palliative care. Most participants also knew their local

consultants in palliative medicine, yet many admitted to

little idea of what they actually did. This may be because

working practices are different in palliative care; the

multi-disciplinary team and the advisory nature of much

496 B Hanratty et al.

of the doctors’ work are better developed than in many

other specialities. However, the strong perception that

end-of-life care is a nursing role may mean that doctors fail to see the relevance to their own work. The specialist

palliative care team may inadvertently reinforce such

perceptions, by the way in which they work. Qualities

that contribute to an effective team � valuing the

contribution of different disciplines, respect for alterna-

tive viewpoints, for example � can also be interpreted as

signs that a doctor is not needed. Hierarchies are still

entrenched in medical practice, and this must underpin many of these challenges.

The hospice movement has been a successful advocate

for the development of holistic care of the dying.

Palliative care has a place in many undergraduate and

postgraduate curricula, albeit limited.18,19 The deficien-

cies of the knowledge base have been well described in

recent years,18�22 and educators are increasingly looking

beyond the sharing of knowledge, to focus on more effective ways of changing behaviour.23,24 Our partici-

pants are likely to be typical of today’s consultants and

GPs, having had little or no formal training in palliative

care. Whilst not lacking knowledge, they displayed

attitudes that may prevent them from providing good

palliative care. For example, the ‘failure’ of death was

discussed, as was the negative focus on survival within

palliative care. For many doctors, the attitudes, beliefs, and self-perceptions that underpin professional practice

may be potent barriers to holistic care.12 Our work

certainly suggests that greater emphasis on these within

educational strategies may be beneficial. Challenging

attitudes to medical roles is a long term project, but

change is more likely as palliative care becomes firmly

established within medical schools. Evaluative research

into the most effective approaches to professional behavioural change within palliative care settings would

be helpful.

Acknowledgements

This study would not have been possible without the

participants giving generously of their time and energy to participate in the focus groups. We gratefully acknowl-

edge financial support from the Mersey Primary Care

Research and Development Consortium and the Scien-

tific Foundation Board of the Royal College of General

Practitioners.

References

1 Bosanquet N. New challenge for palliative care. BMJ 1997; 314: 1294.

2 Fordham S, Dowrick C. Is care of the dying improving? The contribution of specialist and non-specialist to palliative care. Fam Pract 1999; 16: 573�79.

3 Mills M, Davies HTO, Macrae WA. Care of dying

patients in hospital. BMJ 1994; 309: 583�86. 4 Smith R. A good death. BMJ 2000; 320: 129�30. 5 Saunders C. The evolution of palliative care. J R Soc

Med 2001; 94: 430�32. 6 Hospice Information Service Factsheet 3 . Hospice In-

formation Service, 2000. 7 Rogers AE, Addington-Hall JM, Abery AJ, et al .

Knowledge and communication difficulties for patients

with chronic heart failure: qualitative study. BMJ 2000;

321: 605�607. 8 Murray SA, Boyd K, Kendall M, Worth A, Benton TF,

Clausen H. Dying of lung cancer or cardiac failure:

prospective qualitative interview study of patients and

their carers in the community. BMJ 2002; 325: 929. 9 Shipman C, Addington-Hall JM, Barclay S, et al .

Educational opportunities in palliative care, what do

GPs want? Palliat Med 2001; 15: 191�96. 10 Burge F, McIntyre P, Kaufman D, Cummings I, Frager

G, Pollett A. Family medicine residents’ knowledge and

attitudes about end-of-life care. J Palliat Care 2000; 16:

5�12. 11 James CR, Macleod RD. The problematic nature of

education in palliative care. J Palliat Care 1993; 9: 5�10. 12 Hillier R, Wee B. From cradle to grave: palliative

medicine education in the UK. J R Soc Med 2001; 94:

468�71. 13 Greco PJ, Eisenberg JM. Changing physicians’ practices.

N Engl J Med 1993; 329: 1271�74. 14 Graham I. I believe therefore I practise. Lancet 1996;

347: 4�5. 15 Office for National Statistics. Mortality statistics, gen-

eral: review of registrar general on deaths in England and

Wales. Stationery Office, 1998. 16 Fraser D. QSR NVivo reference guide, second edition.

Qualitative Solutions and Research Pty., Ltd., 1999. 17 Glaser BG, Strauss AL. The discovery of grounded

theory: strategies for qualitative research . Aldine, 1967. 18 Barclay S, Todd C, Grande G, Lipscombe J. How

common is medical training in palliative care? Br J Gen

Pract 1997; 47: 805. 19 Lloyd-Williams M, Carter YH. General practice voca-

tional training in the UK: what teaching is given in

palliative care? Palliat Med 2003; 17: 616�20. 20 Herzler M, Franze F, Assadullah K. Dealing with the

issue ‘care of the dying’ in medical education � results of

a survey of 592 European physicians. Med Educ 2000;

34: 146�47. 21 Barclay S, Wyatt P, Shore S, Grande G, Todd C. Caring

for the dying: how well prepared are general practi-

tioners? A questionnaire study in Wales. Palliat Med

2003; 17: 27�39. 22 Oliver D. Training in palliative care. Br J Gen Pract

1998; 48: 1095. 23 MacLeod R. Learning to care: a medical perspective.

Palliat Med 2000; 14: 209�16. 24 Nelson W, Angoff N, Binder E, et al . Goals and

strategies for teaching death and dying in medical

schools. J Palliat Med 2000; 3: 7�16.

Doctors’ understanding of palliative care 497

<< /ASCII85EncodePages false /AllowTransparency false /AutoPositionEPSFiles true /AutoRotatePages /All /Binding /Left /CalGrayProfile (Dot Gain 20%) /CalRGBProfile (sRGB IEC61966-2.1) /CalCMYKProfile (U.S. Web Coated \050SWOP\051 v2) /sRGBProfile (sRGB IEC61966-2.1) /CannotEmbedFontPolicy /Warning /CompatibilityLevel 1.4 /CompressObjects /Tags /CompressPages true /ConvertImagesToIndexed true /PassThroughJPEGImages true /CreateJDFFile false /CreateJobTicket false /DefaultRenderingIntent /Default /DetectBlends true /ColorConversionStrategy /LeaveColorUnchanged /DoThumbnails false /EmbedAllFonts true /EmbedJobOptions true /DSCReportingLevel 0 /EmitDSCWarnings false /EndPage -1 /ImageMemory 1048576 /LockDistillerParams false /MaxSubsetPct 100 /Optimize true /OPM 1 /ParseDSCComments true /ParseDSCCommentsForDocInfo true /PreserveCopyPage true /PreserveEPSInfo true /PreserveHalftoneInfo false /PreserveOPIComments false /PreserveOverprintSettings true /StartPage 1 /SubsetFonts true /TransferFunctionInfo /Apply /UCRandBGInfo /Preserve /UsePrologue false /ColorSettingsFile () /AlwaysEmbed [ true ] /NeverEmbed [ true ] /AntiAliasColorImages false /DownsampleColorImages true /ColorImageDownsampleType /Bicubic /ColorImageResolution 300 /ColorImageDepth -1 /ColorImageDownsampleThreshold 1.50000 /EncodeColorImages true /ColorImageFilter /DCTEncode /AutoFilterColorImages true /ColorImageAutoFilterStrategy /JPEG /ColorACSImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /ColorImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /JPEG2000ColorACSImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /JPEG2000ColorImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /AntiAliasGrayImages false /DownsampleGrayImages true /GrayImageDownsampleType /Bicubic /GrayImageResolution 300 /GrayImageDepth -1 /GrayImageDownsampleThreshold 1.50000 /EncodeGrayImages true /GrayImageFilter /DCTEncode /AutoFilterGrayImages true /GrayImageAutoFilterStrategy /JPEG /GrayACSImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /GrayImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /JPEG2000GrayACSImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /JPEG2000GrayImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /AntiAliasMonoImages false /DownsampleMonoImages true /MonoImageDownsampleType /Bicubic /MonoImageResolution 1200 /MonoImageDepth -1 /MonoImageDownsampleThreshold 1.50000 /EncodeMonoImages true /MonoImageFilter /CCITTFaxEncode /MonoImageDict << /K -1 >> /AllowPSXObjects false /PDFX1aCheck false /PDFX3Check false /PDFXCompliantPDFOnly false /PDFXNoTrimBoxError true /PDFXTrimBoxToMediaBoxOffset [ 0.00000 0.00000 0.00000 0.00000 ] /PDFXSetBleedBoxToMediaBox true /PDFXBleedBoxToTrimBoxOffset [ 0.00000 0.00000 0.00000 0.00000 ] /PDFXOutputIntentProfile () /PDFXOutputCondition () /PDFXRegistryName (http://www.color.org) /PDFXTrapped /Unknown /Description << /FRA <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> /ENU (Use these settings to create PDF documents with higher image resolution for improved printing quality. The PDF documents can be opened with Acrobat and Reader 5.0 and later.) /JPN <FEFF3053306e8a2d5b9a306f30019ad889e350cf5ea6753b50cf3092542b308000200050004400460020658766f830924f5c62103059308b3068304d306b4f7f75283057307e30593002537052376642306e753b8cea3092670059279650306b4fdd306430533068304c3067304d307e305930023053306e8a2d5b9a30674f5c62103057305f00200050004400460020658766f8306f0020004100630072006f0062006100740020304a30883073002000520065006100640065007200200035002e003000204ee5964d30678868793a3067304d307e30593002> /DEU <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> /PTB <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> /DAN <FEFF004200720075006700200064006900730073006500200069006e0064007300740069006c006c0069006e006700650072002000740069006c0020006100740020006f0070007200650074007400650020005000440046002d0064006f006b0075006d0065006e0074006500720020006d006500640020006800f8006a006500720065002000620069006c006c00650064006f0070006c00f80073006e0069006e006700200066006f00720020006100740020006600e50020006200650064007200650020007500640073006b00720069006600740073006b00760061006c0069007400650074002e0020005000440046002d0064006f006b0075006d0065006e0074006500720020006b0061006e002000e50062006e006500730020006d006500640020004100630072006f0062006100740020006f0067002000520065006100640065007200200035002e00300020006f00670020006e0079006500720065002e> /NLD <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> /ESP <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> /SUO <FEFF004e00e4006900640065006e002000610073006500740075007300740065006e0020006100760075006c006c006100200076006f0069006400610061006e0020006c0075006f006400610020005000440046002d0061007300690061006b00690072006a006f006a0061002c0020006a006f006900640065006e002000740075006c006f0073007400750073006c00610061007400750020006f006e0020006b006f0072006b006500610020006a00610020006b007500760061006e0020007400610072006b006b007500750073002000730075007500720069002e0020005000440046002d0061007300690061006b00690072006a0061007400200076006f0069006400610061006e0020006100760061007400610020004100630072006f006200610074002d0020006a00610020004100630072006f006200610074002000520065006100640065007200200035002e00300020002d006f0068006a0065006c006d0061006c006c0061002000740061006900200075007500640065006d006d0061006c006c0061002000760065007200730069006f006c006c0061002e> /ITA <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> /NOR <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> /SVE <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> >> >> setdistillerparams << /HWResolution [2400 2400] /PageSize [612.000 792.000] >> setpagedevice