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Student Name

Date

Questions

Student Response

Part I

Original DNA Strand:

Transcription (base sequence of RNA):

Translation (amino acid sequence):

Mutated gene sequence one:

Transcription (base sequence of RNA):

Translation (amino acid sequence):

Mutated gene sequence two:

Transcription (base sequence of RNA):

Translation (amino acid sequence):

What is the significance of the first and last codons of an mRNA transcript?

Explanation:

What meaning do these mRNA codons have for protein synthesis?

Explanation:

Did the two mutations result in a change in the final proteins? If so, describe the change.

Response/ explanation:

In general, why might a change in amino acid sequence affect protein function?

Explanation:

Part II

Punnett Square

a.       Chances (%) for healthy child, not a carrier

b.      Chances (%) for child that is carrier for cystic fibrosis trait

c.       Chances (%) for child with cystic fibrosis

Fill out/adapt Punnett Square:

a.       Chances (%) for healthy child, not a carrier:

b.      % for child that is carrier for cystic fibrosis trait:      

c.       % for child with cystic fibrosis:      

Part III: Essay

How do both meiosis and sexual reproduction (fertilization) produce offspring that differ genetically from the parents?

·         Include steps in meiosis that increase variability

·         Include the process of fertilization.

Explanation: