"Interoperability" Please respond to the following:

1, Elaborate on the trend of interoperability of health care management information systems. Determine a significant challenge that health care organizations will face when creating an interoperable system. Justify your response.

2, Suggest a significant benefit of interoperability that is the result of the SAPHIRE project. Provide support for your rationale.

3, Determine the most significant requirement of an effective solution to interoperability. Provide a rationale for your determination.

4, Suggest a significant challenge of applying WSIHS to health care management information systems (HMIS), and indicate how the challenge may be mitigated.